scholarly journals Resistant Chorea Successfully Treated with Intravenous Immunoglobulin: A Case Report

2021 ◽  
pp. 117-120
Author(s):  
Ahmet Sami Güven ◽  
Mehmet Burhan Oflaz ◽  
Ali Kaya ◽  
Fatih Bolat ◽  
Utku Aygüneş ◽  
...  

Sydenham’s chorea (SC) is common cause of acquired chorea in childhood. SC occurs mainly in children with untreated streptococcal infections. An effective list of therapeutic options has been used to treat this disorder: antiepileptic drugs (valproic acid, carbamazepine etc.), haloperidol, chlorpromazine, amphetamines, steroids, plasma exchange and intravenous immunoglobulins (IVIG). We report a 12-year-old girl with carditis and severely generalized chorea and successfully treated with IVIG. This case report shows that IVIG is an effective treatment for the chorea cases resistant to anticonvulsants, dopamine antagonists and steroids, although larger studies are needed to confirm this conclusion.

PM&R ◽  
2010 ◽  
Vol 2 ◽  
pp. S143-S143
Author(s):  
Henry A. Richardson ◽  
Ziyad Ayyoub ◽  
Ramzi Ben-Youssef ◽  
Murray Brandstater ◽  
Ake Evans ◽  
...  

2013 ◽  
Vol 20 (4) ◽  
pp. 501-504 ◽  
Author(s):  
Liene Elsone ◽  
Jay Panicker ◽  
Kerry Mutch ◽  
Mike Boggild ◽  
Richard Appleton ◽  
...  

Prompt treatment of neuromyelitis optica (NMO) relapses with steroids or plasma exchange (PLEX) often prevents irreversible disability. The objective of this study is to report the use of intravenous immunoglobulins (IVIG) as treatment for acute relapses in NMO. A retrospective review of 10 patients treated with IVIG for acute relapses was conducted. IVIG was used in the majority of cases because of lack of response to steroids with/without PLEX. Improvement was noted in five of 11 (45.5%) events; the remaining had no further worsening. One patient, a 79-year-old woman, had a myocardial infarction seven days after IVIG. IVIG may have a role in treating acute NMO relapses.


2020 ◽  
Vol 47 (5) ◽  
pp. 420-423 ◽  
Author(s):  
Parmatma Prasad Tripathi ◽  
Rekha Hans ◽  
Ratti Ram Sharma ◽  
Divjot Singh Lamba ◽  
Preeti Paul ◽  
...  

Background: Acute disseminated encephalomyelitis (ADEM) is a demyelinating disease usually affecting children and is treated with high-dose steroid therapy. Case Report: An 8-year boy presented with limbs weakness and complete loss of vision and was resistant to steroid therapy. He was further treated with plasma exchange and showed full recovery from the neurological deficit. Conclusion: Therapeutic plasma exchange appears to be effective in ADEM patients in reversing the neuropathological process especially refractory to steroids and intravenous immunoglobulin.


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