Why should we care about Carrying Capacity? A novel screening tool for the health risk in recreational waters near estuary

Author(s):  
Morena Galešić ◽  
Mariaines Di Dato ◽  
Roko Andričević

<p>The present work proposes a novel screening tool to improve the quality of recreational coastal water. Indeed, the recreational potential of beach resort depends on its health status, which in marine cities may be threatened by increasing stress produced by anthropogenic activity. In particular, we focus on the beach near an estuary, which may be affected by a considerable load of contaminants, especially when the urban sewage system is combined and designed to spill untreated wastewater directly in the coastal water. In a few words, when the Combined Sewer Overflows (CSOs) are activated, the bacterial concentration in the estuary increases, thereby resulting in a potential hazard for the swimmers’ health. In the present work, the bacterial transport is modelled through a physically-based stochastic framework, whereas the human health risk is evaluated by means of the Quantitative Microbial Risk Assessment (QMRA). As the human health risk is quantified, it is used to evaluate the Carrying Capacity indicator of the recreational coastal water. This indicator is defined as the number of swimmers that can be sustained by coastal water with an acceptable risk threshold. The results indicate that the Carrying Capacity increases by dilution processes and by reduction of the source concentration. This indicator may be viewed as a screening tool for policy-makers and other stakeholders. For instance, it can help to balance the resources needed to improve the sewage-system and the benefits coming from tourism and sustainable environmental policies, given that the beach quality, in turn, depends on the improvements in the sewage system.</p>

2015 ◽  
Vol 34 (5) ◽  
pp. 384-392 ◽  
Author(s):  
Senthilkumar P. Kuppusamy ◽  
J. Phillip Kaiser ◽  
Scott C. Wesselkamper

Although several studies have shown that chemically mediated epigenetic changes are an etiological factor in several human disease conditions, the utility of epigenetic data, such as DNA methylation, in the current human health risk assessment paradigm is unclear. The objective of this study is to investigate the relationship between the points of departure (PODs) for cancer incidence and DNA methylation changes in laboratory animals exposed to the following environmental toxicants: bromodichloromethane, dibromochloromethane, chloroform, hydrazine, trichloroethylene, benzidine, trichloroacetic acid, and di(2-ethylhexyl) phthalate (DEHP; a known reproductive toxicant). The results demonstrate that the PODs for cancer incidence and altered DNA methylation are similar. Furthermore, based on the available data, the POD for DNA methylation appeared more sensitive compared to that for cancer incidence following the administration of DEHP to rats during different life stages. The high degree of correlation between PODs for cancer incidence and DNA methylation (for both total DNA and individual genes) suggests that DNA methylation end points could potentially be used as a screening tool in predicting the potential toxicity/carcinogenicity and in prioritizing large numbers of chemicals with sparse toxicity databases. The life stage during which treatment occurs is also an important consideration when assessing the potential application of epigenetic end points as a screening tool.


2020 ◽  
Vol 8 (F) ◽  
pp. 143-154
Author(s):  
Ratna Dwi Puji Astuti

BACKGROUND: Water is one of the basic materials of human existence. In respect this, many countries have been focused on water security agenda as one of the national strategic security. One of water security domains is coastal water security. Water security, due to the myriad of factors influencing water quantity and quality in coastal area, can be considered as a complex system. Due to the complexity and dynamic characteristic, system dynamic model (SDM) is needed to implement in coastal area to integrate all subsystem. AIM: This study aims to analyse the subsystems relating to coastal water security. The subsystem determination used to develop future policy-making relating to coastal water security. METHODS: For this purpose, a systematic literature review was conducted and a set of 12 papers was selected from 2009 – 2019. RESULTS: The papers’ analysis shows the applicability of SDM to solve complex problems. Water scarcity has been identified as a major problem in the coastal area, identified in eight papers. Three papers are related to water quality and only one paper relating to both. There are four major subsystems relating to coastal water security: environment, economic, social, and politic. Information about the aquaculture activities, the mechanism of coastal water pollution and water relating human health risk is still limited. CONCLUSION: We recommend use of SDM in the coastal water security to be extended to aquaculture, coastal water pollution and human health risk aspect in order to promote a holistic understanding of the complex issues and to develop more effective policies.


2006 ◽  
Vol 14 (2) ◽  
pp. 559-570 ◽  
Author(s):  
F. Quercia ◽  
A. Vecchio ◽  
M. Falconi ◽  
L. Togni ◽  
E. Wcislo ◽  
...  

Author(s):  
Quang Phan Dinh ◽  
Sylvester Addai‐Arhin ◽  
Huiho Jeong ◽  
Willy Cahya Nugraha ◽  
Pham Hung Viet ◽  
...  

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