scholarly journals Tracking HIV Post-Exposure Prophylaxis using Syndromic Surveillance in NYC Emergency Departments

Author(s):  
Stephanie Ngai ◽  
Zoe Edelstein ◽  
Julie Myers ◽  
Don Weiss

HIV post-exposure prophylaxis (PEP) prescriptions are not uniformly monitored in the United States. We developed a method to identify PEP-related visits in New York City emergency departments (EDs). Using ED data, we observed a threefold increase in PEP-related visits to NYC EDs from 2002-2013. 73% of PEP-related visits were among males, and 45% among adults ages 25-34 years. Incorporation of this method of PEP monitoring in the NYC syndromic surveillance system will be used to observe trends and inform HIV outreach efforts.

2020 ◽  
Vol 31 (2) ◽  
pp. 672-681
Author(s):  
Matthew A. Adan ◽  
Jason Zucker ◽  
Caroline Carnevale ◽  
William L. Grant ◽  
Alwyn T. Cohall ◽  
...  

2017 ◽  
Vol 65 (11) ◽  
pp. 1843-1847 ◽  
Author(s):  
Robert J Arciuolo ◽  
Rachel R Jablonski ◽  
Jane R Zucker ◽  
Jennifer B Rosen

2018 ◽  
Vol 22 (8) ◽  
pp. 2718-2732 ◽  
Author(s):  
Beryl A. Koblin ◽  
DaShawn Usher ◽  
Vijay Nandi ◽  
Hong-Van Tieu ◽  
Eddie Bravo ◽  
...  

2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S20-S21
Author(s):  
Allison Glaser ◽  
Emma Kaplan-Lewis ◽  
Ana Ventuneac ◽  
Wyley Gates ◽  
Michael Cruz ◽  
...  

Abstract Background Oral post-exposure prophylaxis (PEP) is effective in preventing HIV transmission. To minimize barriers to PEP for New York City (NYC) residents, the Institute for Advanced Medicine (IAM), Mount Sinai Health System, and the NYC Department of Health and Mental Health established a 24-hour 7-days PEP hotline to provide eligible callers with immediate access to PEP and follow-up clinical care. Methods Data from hotline callers (January to December 2017) was analyzed utilizing multivariable logistic regression to determine whether a call resulted in PEP access within 72 hours of exposure by sociodemographic variables and exposure characteristics. We describe transitions from PEP to PrEP (pre-exposure prophylaxis). Results The PEP hotline cohort (n = 1278) was 83% male, 11% female, 1% transgender; 66% LGBTQ and 20% heterosexual; 35% White, 15% Black, 9% Asian; 41% other/unknown; 25% Hispanic; mean age of 30 years (range 14–72). The majority of callers learned about the hotline by Internet search (59%). Mean exposure time prior to call was 31 hours with 57% within 24 hours. Exposures were 98% sexual; 73% anal sex (43% receptive; 30% insertive), 21% vaginal, and 6% other. 63% reported condomless sex and 29% condom failure. 15% of callers reported a partner with HIV. 35% of callers reported alcohol or recreational substances at the time of the exposure. Prior PEP and PrEP use was 20% and 9%, respectively. 91% of callers were eligible for PEP; 69% called afterhours and received a telephone PEP prescription, and 27% called during business hours and were directed to a clinic. Access to PEP within 72 hours of exposure occurred in 1,081 (93%) of eligible callers and within 36 hours in 68%. 90% of callers had confirmed follow-up clinic appointments. Of the 472 callers linked to care at the IAM, 89 (19%) transitioned to PrEP. Conclusion This unique program demonstrates a timely initiative to facilitate PEP access to a diverse cohort with the purpose of mitigating risk from potential exposure to HIV. Further investigation is needed to explore adherence to PEP, follow-up testing results, transitions to PrEP for prevention planning, and coordination of health care and substance use services. Disclosures E. Kaplan-Lewis, Viiv: Consultant, Consulting fee. J. Aberg, Gilead: Research Contractor, Research support. GSK: Research Contractor, Research support. ViiV: Research Contractor, Research support. A. Urbina, Theratechnologies: Scientific Advisor, Consulting fee. ViiV: Scientific Advisor, Consulting fee. Merck: Scientific Advisor, Consulting fee. Gilead: Scientific Advisor, Consulting fee.


Viruses ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 450
Author(s):  
Scott Brunt ◽  
Heather Solomon ◽  
Kathleen Brown ◽  
April Davis

In New York State, domestic animals are no longer considered rabies vector species, but given their ubiquity with humans, rabies cases in dogs and cats often result in multiple individuals requiring post-exposure prophylaxis. For over a decade, the New York State rabies laboratory has variant-typed these domestic animals to aid in epidemiological investigations, determine exposures, and generate demographic data. We produced a data set that outlined vaccination status, ownership, and rabies results. Our data demonstrate that a large percentage of felines submitted for rabies testing were not vaccinated or did not have a current rabies vaccination, while canines were largely vaccinated. Despite massive vaccination campaigns, free clinics, and education, these companion animals still occasionally contract rabies. Barring translocation events, we note that rabies-positive cats and dogs in New York State have exclusively contracted a raccoon variant. While the United States has made tremendous strides in reducing its rabies burden, we hope these data will encourage responsible pet ownership including rabies vaccinations to reduce unnecessary animal mortality, long quarantines, and post-exposure prophylaxis in humans.


Author(s):  
Laura J. Fitzpatrick ◽  
Daniel J. Egan ◽  
Ethan Cowan ◽  
Leah M. Savitsky ◽  
John D. Kushner ◽  
...  

Author(s):  
Robert Mathes ◽  
Jessica Sell ◽  
Anthony W. Tam ◽  
Alison Levin-Rector ◽  
Ramona Lall

The New York City (NYC) syndromic surveillance system has been monitoring syndromes from city emergency department (ED) visits since 2001. We conducted an evaluation of statistical aberration detection methods currently in use in our system as well as alternative methods, applying six temporal and four spatio-temporal aberration detection methods to two years of ED visits in NYC spiked with synthetic outbreaks. We found performance varied between the methods in regard to sensitivity, specificity, and timeliness, and implementation of these methods will depend on needs, frequency of signals, and technical skill.


2019 ◽  
Vol 14 (1) ◽  
pp. 44-48
Author(s):  
Priscilla W. Wong ◽  
Hilary B. Parton

ABSTRACTObjective:Syndromic surveillance has been useful for routine surveillance on a variety of health outcomes and for informing situational awareness during public health emergencies. Following the landfall of Hurricane Maria in 2017, the New York City (NYC) Department of Health and Mental Hygiene (DOHMH) implemented an enhanced syndromic surveillance system to characterize related emergency department (ED) visits.Methods:ED visits with any mention of specific key words (“Puerto,” “Rico,” “hurricane,” “Maria”) in the ED chief complaint or Puerto Rico patient home Zip Code were identified from the DOHMH syndromic surveillance system in the 8-week window leading up to and following landfall. Visit volume comparisons pre- and post-Hurricane Maria were performed using Fisher’s exact test.Results:Analyses identified an overall increase in NYC ED utilization relating to Puerto Rico following Hurricane Maria landfall. In particular, there was a small but significant increase in visits involving a medication refill or essential medical equipment. Visits for other outcomes, such as mental illness, also increased, but the differences were not statistically significant.Conclusions:Gaining this situational awareness of medical service use was informative following Hurricane Maria, and, following any natural disaster, the same surveillance methods could be easily established to aid an effective emergency response.


Vaccine ◽  
2008 ◽  
Vol 26 (33) ◽  
pp. 4251-4255 ◽  
Author(s):  
Praveen Dhankhar ◽  
Sagar A. Vaidya ◽  
Daniel B. Fishbien ◽  
Martin I. Meltzer

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