scholarly journals Reinfection of SARS-CoV-2 in a health care worker: A case report

2021 ◽  
Vol 2 (2) ◽  
Author(s):  
Steffen Höring ◽  
◽  
Doris Keller ◽  
Michael Kleines ◽  
◽  
...  
Keyword(s):  
Health Care ◽  
Case Report ◽  
Health Care Worker ◽  
Post Infection ◽  
Clinical Impact ◽  
First Episode ◽  
Specific Antibodies ◽  
Care Worker

Coronavirus-specific antibodies decline fast and allow reinfection starting 6 months post infection. Knowledge on reinfection is very important for SARS-CoV-2. Here we report a reinfection with SARS-CoV-2 of a 23 years old female health care worker 177 days after the onset of the first episode. The second episode was clinically more severe as the first episode. Our data show that reinfection with SARS-CoV-2 can occur with increased clinical impact in immunocompetent, young individuals after less than half a year.

scholarly journals Peritoneal tuberculosis in a health-care worker, radio-pathological assessment and diagnosis, a case report

2019 ◽  
Vol 6 (4) ◽  
pp. 163-169
Author(s):  
Leonardo F. Jurado ◽  
Bibiana Pinzón ◽  
Zandra R. De La Rosa-Noriega ◽  
Eugenio Matijasevic ◽  
Rocío del Pilar López-Panqueva
Keyword(s):  
Health Care ◽  
Case Report ◽  
Health Care Worker ◽  
Peritoneal Tuberculosis ◽  
Care Worker ◽  
Pathological Assessment ◽  
Assessment And Diagnosis

scholarly journals Symptomatic SARS-CoV-2 re-infection of a health care worker in a Belgian nosocomial outbreak despite primary neutralizing antibody response

2020 ◽  
Author(s):  
Philippe Selhorst ◽  
Sabrina Van Ierssel ◽  
Jo Michiels ◽  
Joachim Mariën ◽  
Koen Bartholomeeusen ◽  
...  
Keyword(s):  
Health Care ◽  
Immune Response ◽  
Health Care Worker ◽  
Neutralizing Antibodies ◽  
Primary Infection ◽  
Rare Event ◽  
Neutralizing Antibody ◽  
First Episode ◽  
Nosocomial Outbreak ◽  
Care Worker

AbstractBackgroundIt is currently unclear whether SARS-CoV-2 re-infection will remain a rare event, only occurring in individuals who fail to mount an effective immune response, or whether it will occur more frequently when humoral immunity wanes following primary infection.MethodsA case of re-infection was observed in a Belgian nosocomial outbreak involving 3 patients and 2 health care workers. To distinguish re-infection from persistent infection and detect potential transmission clusters, whole genome sequencing was performed on nasopharyngeal swabs of all individuals including the re-infection case’s first episode. IgA, IgM, and IgG and neutralizing antibody responses were quantified in serum of all individuals, and viral infectiousness was measured in the swabs of the reinfection case.ResultsRe-infection was confirmed in a young, immunocompetent health care worker as viral genomes derived from the first and second episode belonged to different SARS-CoV-2 clades. The symptomatic re-infection occurred after an interval of 185 days, despite the development of an effective humoral immune response following symptomatic primary infection. The second episode, however, was milder and characterized by a fast rise in serum IgG and neutralizing antibodies. Although contact tracing and virus culture remained inconclusive, the health care worker formed a transmission cluster with 3 patients and showed evidence of virus replication but not of neutralizing antibodies in her nasopharyngeal swabs.ConclusionIf this case is representative of most Covid-19 patients, long-lived protective immunity against SARS-CoV-2 might not be likely.

scholarly journals Symptomatic SARS-CoV-2 reinfection of a health care worker in a Belgian nosocomial outbreak despite primary neutralizing antibody response

2020 ◽  
Author(s):  
Philippe Selhorst ◽  
Sabrina Van Ierssel ◽  
Jo Michiels ◽  
Joachim Mariën ◽  
Koen Bartholomeeusen ◽  
...  
Keyword(s):  
Health Care ◽  
Immune Response ◽  
Health Care Worker ◽  
Neutralizing Antibodies ◽  
Primary Infection ◽  
Rare Event ◽  
Neutralizing Antibody ◽  
First Episode ◽  
Nosocomial Outbreak ◽  
Care Worker

Abstract Background It is currently unclear whether SARS-CoV-2 reinfection will remain a rare event, only occurring in individuals who fail to mount an effective immune response, or whether it will occur more frequently when humoral immunity wanes following primary infection. Methods A case of reinfection was observed in a Belgian nosocomial outbreak involving 3 patients and 2 health care workers. To distinguish reinfection from persistent infection and detect potential transmission clusters, whole genome sequencing was performed on nasopharyngeal swabs of all individuals including the reinfection case’s first episode. IgA, IgM, and IgG and neutralizing antibody responses were quantified in serum of all individuals, and viral infectiousness was measured in the swabs of the reinfection case. Results Reinfection was confirmed in a young, immunocompetent health care worker as viral genomes derived from the first and second episode belonged to different SARS-CoV-2 clades. The symptomatic reinfection occurred after an interval of 185 days, despite the development of an effective humoral immune response following symptomatic primary infection. The second episode, however, was milder and characterized by a fast rise in serum IgG and neutralizing antibodies. Although contact tracing and virus culture remained inconclusive, the health care worker formed a transmission cluster with 3 patients and showed evidence of virus replication but not of neutralizing antibodies in her nasopharyngeal swabs. Conclusion If this case is representative of most Covid-19 patients, long-lived protective immunity against SARS-CoV-2 after primary infection might not be likely.

scholarly journals Invasive Group A Streptococcal Infections in Sacral Pressure Ulcer of an Elderly Person Supported by a Health Care Worker: A Case Report

2017 ◽  
Vol 76 (5) ◽  
pp. 225-227
Author(s):  
Atsunori Sugita ◽  
Kosaku Kinoshita ◽  
Tomohide Komatsu ◽  
Rumi Tagami ◽  
Shingo Ihara ◽  
...  
Keyword(s):  
Health Care ◽  
Case Report ◽  
Health Care Worker ◽  
Pressure Ulcer ◽  
Elderly Person ◽  
Streptococcal Infections ◽  
Invasive Group ◽  
Group A ◽  
Care Worker

ANAPHYLAXIS TO LATEX IN A HEALTH CARE WORKER. CASE REPORT AND REVIEW

1991 ◽  
Vol 84 (Supplement) ◽  
pp. 5
Author(s):  
Donald T. Brothers ◽  
Michael S. Blaiss
Keyword(s):  
Health Care ◽  
Case Report ◽  
Health Care Worker ◽  
Care Worker

scholarly journals Recurrent COVID-19 infection in a health care worker: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Jaya Garg ◽  
Jyotsna Agarwal ◽  
Anupam Das ◽  
Manodeep Sen
Keyword(s):  
Health Care ◽  
Immune Response ◽  
Health Care Worker ◽  
Interesting Case ◽  
Antibody Detection ◽  
First Episode ◽  
Igg Antibody ◽  
Viral Shedding ◽  
Different Strains ◽  
Care Worker

Abstract Background Recurrent coronavirus disease 2019 (COVID-19) infection is an emerging problem and may prove to be one of the greatest problems in controlling the pandemic in the future. Recurrent infections can be due to reactivation of dormant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or reinfection with similar or different strains of SARS-CoV-2. Case presentation Here we present an interesting case of a health care worker working as a laboratory assistant at a COVID-19 laboratory who developed recurrent COVID-19 infection. He did not develop an immune response after the first episode of COVID-19; however, immunoglobulin G (IgG) antibodies were detected after the second episode. Conclusions Through this case, we discuss the concept of reactivation and reinfection in the post-COVID period. We suggest that standard guidelines should be established to check for viral shedding and immune response among cured cases of COVID-19 after discharge via serial real-time polymerase chain reaction (RT-PCR) testing and IgG antibody detection. Further, strict hygiene practices should be stressed to these patients with possibility of COVID-19 recurrence.

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