scholarly journals Accuracy of the Chula's formula for calculation of standard liver volume in Thai population

2021 ◽  
Vol 1 (2) ◽  
Author(s):  
Malinee Chuesaard ◽  
◽  
Natthaporn Tanpowpong ◽  
Keyword(s):  
Body Weight ◽  
Living Donor ◽  
Liver Volume ◽  
Graft Function ◽  
High Accuracy ◽  
Accurate Estimation ◽  
Volumetric Measurement ◽  
Thai Population ◽  
Total Liver Volume ◽  
Standard Liver Volume

Background: Standard liver volume (SLV) is an important concept in living donor liver transplantation for treatment of end-stage liver disease. Accurate estimation of the SLV of living donor and recipient is crucial to ensure optimal graft function and avoid complications. Objective: 1) to assess the proposed formula for calculation of SLV in Thai population, using computed tomography (CT) volumetric measurement as a gold standard. 2) to evaluate the factors (e.g. age, sex, body weight and body surface area) related to differences between SLV calculated from the proposed formula and CT volumetric measurement. Materials and methods: We evaluated 497 patients underwent contrast-enhanced abdominal multi-detector CT for conditions unrelated to hepatobiliary system with normal liver radiology between October 1, 2014 and August 31, 2015 were included. Calculated SLV by the proposed formula (SLV = 20.76 x body weight) were compared to the total liver volume (TLV) measured from multi-detector CT by using computerized tool automatically. Factors related to the difference between SLV and TLV were evaluated. Result: The aforementioned formula showed a high accuracy in estimating the liver volume with some limitations in overweight or underwent patients. The mean difference between SLV and TLV is 3.36 cm3 with SD of 224.65 cm3. Conclusion: We proposed a new formula ("Chula's standard liver volume") that demonstrates a high accuracy for calculation of SLV in Thai population. Keywords: Liver volume; MDCT; standard liver volume; Thai population

A new formula for calculating standard liver volume for living donor liver transplantation without using body weight

2015 ◽  
Vol 63 (4) ◽  
pp. 848-854 ◽  
Author(s):  
Takashi Kokudo ◽  
Kiyoshi Hasegawa ◽  
Emilie Uldry ◽  
Yutaka Matsuyama ◽  
Junichi Kaneko ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Body Weight ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Liver Volume ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Standard Liver Volume ◽  
New Formula

Reliable Estimation of Preoperative Graft Volume in Living Donor Liver Transplantation

2021 ◽  
Vol 15 (11) ◽  
pp. 3030-3033
Author(s):  
Amer Latif ◽  
M Akif Dilshad ◽  
Sumbul Naz ◽  
Sadia Jabbar ◽  
Faisal Naseer ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Living Donor ◽  
Liver Volume ◽  
Volume Estimation ◽  
Accurate Estimation ◽  
Donor Liver ◽  
Living Donor Liver Transplant ◽  
Right Lobe ◽  
Graft Weight ◽  
Donor Liver Transplant

Aims & Objectives: Corner stone in performing living donor liver transplant is to assess and predict the adequacy of the donated liver for recipient and remaining liver. Previously the conversion of liver volume to estimated weight is done by using unit to unit conversion with a factor of 1. We analyzed data of our institute to research the methodology and local applicability of the same. Place and duration of study: Shaikh Zayed Hospital, Lahore. January 2011 to June 2017 Material & Methods: Retrospective data was collected for the first 115 recipients and donors. Their preoperative liver volumes calculated by C.T scan and post-operative graft harvested with weights were compared. Results: The parameter of actual volume of right lobe averaged to 769.77 ± 12.73 gm varying with a quantum of 17.73% (426 – 1123 gm). Estimated volume of right lobe of liver varied 358 to 1218 ml (CV = 17.84%) with an average value of 798.96 ± 13.29 ml. Results of linear regression between estimated volume of right lobe and actual weight of the right lobe in gm was significantly linear (r = 0.830, r2 = 0.690, adj. r2 = 0.689 and F = 250.98, p < 0.0001), showing that volumetric assessment overestimated graft weight/volume. Following is equation generated from our data for graft weight estimation. Actual right lobe (g) = 134.004 + 0.796 (estimated right lobe volume (ml) ± 76.42. Conclusion: Using one to one principle for volume estimation of healthy liver can be misleading and therefore we propose an equation to reach more accurate estimation of graft weight. Keywords: living donor liver transplant, CT volumetry, graft to body weight ratio

scholarly journals Increasing the remnant liver volume using portal vein embolization

2010 ◽  
Vol 4 (5) ◽  
pp. 817-820
Author(s):  
Thanis Saksirinukul ◽  
Permyot Kosolbhand ◽  
Natthaporn Tanpowpong
Keyword(s):  
Portal Vein ◽  
Portal Vein Embolization ◽  
Major Hepatectomy ◽  
Liver Volume ◽  
Measurement Methods ◽  
Remnant Liver ◽  
Extended Hepatectomy ◽  
Volumetric Measurement ◽  
Common Procedure ◽  
Total Liver Volume

Abstract Background: Portal vein embolization (PVE) is a common procedure to induce hypertrophy of the remnant liver (RL) before major hepatectomy. Objective: Evaluate increased RL volume after PVE based on CT volumetric measurement. Methods: Multi-detector computed tomography (MDCT) was used to measure hepatic volumetric measurement, including total liver volume and RL volumes of pre- and post-PVE. Complications were recorded from PVE and from three-month after post-extended hepatectomy liver dysfunction. Result and conclusion: There was a 10% increase in RL volume. Mean days between CT and PVE were 20 days. No major complications from PVE were observed.

scholarly journals Ratio of remnant to total liver volume or remnant to body weight: which one is more predictive on donor outcomes?

HPB ◽  
2012 ◽  
Vol 14 (7) ◽  
pp. 476-482 ◽  
Author(s):  
Onur Yaprak ◽  
Necdet Guler ◽  
Gulum Altaca ◽  
Murat Dayangac ◽  
Tolga Demirbas ◽  
...  
Keyword(s):  
Body Weight ◽  
Liver Volume ◽  
Total Liver Volume ◽  
Total Liver

scholarly journals Portal vein stenosis preconditioning of living donor liver in swine: early mechanisms of liver regeneration and gain of hepatic functional mass

2018 ◽  
Vol 315 (1) ◽  
pp. G117-G125
Author(s):  
Pauline Brige ◽  
Geraldine Hery ◽  
Anais Palen ◽  
Théophile Guilbaud ◽  
Christophe Buffat ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Portal Vein ◽  
Living Donor ◽  
Liver Volume ◽  
Donor Liver ◽  
Total Liver Volume ◽  
Portal Vein Stenosis ◽  
Preconditioning Method ◽  
Left Portal Vein ◽  
Vein Stenosis

To reduce the morbidity and mortality risk for the donor in living donor liver transplantation (LDLT), we previously identified 20% left portal vein (LPV) stenosis as an effective preconditioning method to induce cell proliferation in the contralateral lobe without downstream ipsilateral atrophy. In this study, we report the pathways involved in the first hours after preconditioning and investigate the changes in liver volume and function. Fourteen pigs were used this study. Five pigs were used to study the genetic, cellular and molecular mechanisms set up in the early hours following the establishment of our preconditioning. The remaining nine pigs were equally divided into three groups: sham-operated animals, 20% LPV stenosis, and 100% LPV stenosis. Volumetric scanning and 99 mTc-Mebrofenin hepatobiliary scintigraphy were performed before preconditioning and 14 days after to study morphological and functional changes in the liver. We demonstrated that liver regeneration triggered by 20% LPV stenosis in the contralateral lobe involves TNF-α, IL-6, and inducible nitric oxide synthase 2 by means of STAT3 and hepatocyte growth factor. We confirmed that our preconditioning was responsible for an increase in the total liver volume. Finally, we demonstrated that this volumetric gain was associated with an increase in hepatic functional capacity. NEW & NOTEWORTHY We describe a new preconditioning method for major hepatectomy that is applicable to hepatectomy for donation. We identified 20% left portal vein stenosis as effective preconditioning that is capable of inducing cell proliferation in the contralateral lobe without the downstream ipsilateral atrophy. In this study, we report the pathways involved in the first hours following preconditioning, and we confirm that 20% left portal vein stenosis is responsible for an increase in the functional capacity and total liver volume in a porcine model.

scholarly journals EFFECT OF PRE-TRANSPLANT SARCOPENIA ON THE ESTIMATION OF THE STANDARD LIVER VOLUME IN LIVING-DONOR LIVER TRANSPLANT CANDIDATES

2020 ◽  
Vol 104 (S3) ◽  
pp. S528-S528
Author(s):  
Masaaki Hidaka ◽  
Riccardo Pravisani ◽  
Takanobu Hara ◽  
Tota Kugiyama ◽  
Takashi Hamada ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Living Donor ◽  
Liver Volume ◽  
Donor Liver ◽  
Living Donor Liver Transplant ◽  
Standard Liver Volume ◽  
Transplant Candidates ◽  
Donor Liver Transplant
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