scholarly journals Management of Pemphigus Vulgaris Using Dexamethasone Cyclophosphamide Pulse Therapy: A Case Report

2021 ◽  
Vol 12 (5) ◽  
pp. 275-277
Author(s):  
Kriti Sareen ◽  
Fozia Sultana ◽  
Zabin Mirza ◽  
Kalpna Thakur ◽  
Ekta Parmar ◽  
...  
Keyword(s):  
Case Report ◽  
Pemphigus Vulgaris ◽  
Pulse Therapy ◽  
Cyclophosphamide Pulse Therapy ◽  
Cyclophosphamide Pulse

Water intoxication associated with moderate dose of cyclophosphamide pulse therapy in an elderly patient: a case report and literature review

2005 ◽  
Vol 15 (1) ◽  
pp. 65-68
Author(s):  
Kunio Yanagisawa ◽  
Keiju Hiromura ◽  
Hiroaki Yagi ◽  
Akihiko Yokohama ◽  
Yoriaki Kaneko ◽  
...  
Keyword(s):  
Elderly Patient ◽  
Case Report ◽  
Literature Review ◽  
Pulse Therapy ◽  
Water Intoxication ◽  
Moderate Dose ◽  
Cyclophosphamide Pulse Therapy ◽  
Cyclophosphamide Pulse

scholarly journals Pulse therapy in pemphigus: report of 11 cases

2013 ◽  
Vol 88 (4) ◽  
pp. 672-675 ◽  
Author(s):  
Nurimar Conceicao Fernandes ◽  
Mariana Menezes
Keyword(s):  
Side Effects ◽  
Maintenance Dose ◽  
Pemphigus Vulgaris ◽  
Pulse Therapy ◽  
Stevens Johnson Syndrome ◽  
Pemphigus Foliaceus ◽  
Cyclophosphamide Pulse Therapy ◽  
Johnson Syndrome ◽  
Cyclophosphamide Pulse

In this study, five cases of pemphigus vulgaris and two cases of pemphigus foliaceus were treated with cyclophosphamide pulse therapy associated with prednisone, resulting in the need for a smaller maintenance dose of prednisone. In three cases of pemphigus vulgaris and one case of pemphigus foliaceus, dexamethasone and cyclophosphamide pulse therapy associated with prednisone helped the lesions to heal more rapidly. Neither treatment however prevented the recurrence of the disease. Amenorrhea, myelotoxicity and Stevens-Johnson syndrome were among the cyclophosphamide side effects. All the patients treated with prednisone experienced known side effects.

scholarly journals Managing the challenging cases of pemphigus vulgaris with modified pulse therapy: case series

2019 ◽  
Vol 5 (2) ◽  
pp. 434
Author(s):  
Saraswathy P. ◽  
Jayanthi N. S. ◽  
Venkatesh Y.
Keyword(s):  
Therapeutic Response ◽  
Case Series ◽  
Pemphigus Vulgaris ◽  
Pulse Therapy ◽  
Patient Needs ◽  
Skin Infections ◽  
The Third ◽  
Cyclophosphamide Pulse Therapy ◽  
First Case ◽  
Cyclophosphamide Pulse

<p class="abstract">In pemphigus vulgaris, pulse therapy is a promising modality to achieve better therapeutic response and to minimize the side effects of daily steroids. Here we report 5 different challenging situations where we successfully managed with modification of pulse therapy. Our first case had multiple comorbidities with persistent skin infections managed with dexamethasone and cyclophosphamide pulse (DCP) and interval pulse. The second case was unmarried hypertensive male with poor DLQI managed with Azathioprine pulse therapy. The third case was uncontrolled diabetic patient with pulmonary tuberculosis managed with rituximab. The fourth case was diabetic and hypertensive was managed with one day dexamethasone cyclophosphamide pulse therapy (DCP). The fifth case was not completed family with cushingoid features managed with dexamethasone azathioprine pulse therapy (DAP). Pulse therapy is effective in controlling disease activity in pemphigus. But it can be modified in some situations according to the patient needs.</p>

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