Comparison of Early Outcomes in Del Nido Cardioplegia Versus Conventional Cardioplegia in Term of MP in Patients

2021 ◽  
Vol 15 (12) ◽  
pp. 3373-3374
Author(s):  
Syed Sardar Rahim ◽  
Ahmad Kamran Khan ◽  
Malik Salman ◽  
Furqan Yaqub Pannu ◽  
Bilal Ahmed ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Troponin I ◽  
Artery Bypass ◽  
P Value ◽  
Bypass Grafting ◽  
Artery Bypass Grafting ◽  
Significant Difference ◽  
The Mean

Objective: To compare early outcomes in antegrade conventional crystalloid cardioplegia with Del Nido (DN) cardioplegia in term of myocardial protection in patients undergoing CABG. Methodology: All the patients undergoing Coronary artery bypass grafting surgery were enrolled in this study after informed consent. Preoperative, intra-operative and postoperative variables were entered in the pre-designed proforma and patients were followed to compare early outcomes in Del-Nido versus Conventional Cardioplegia. Results: The mean age of the patients in Del Nido group was 54.61 ± 9.129 whereas the mean age of the patients in Conventional Cardioplegia group was 53.91 ± 10.39. There were 50(71.43%) males and 20(28.57%) females in Del-Nido group as compare with Conventional group 52(74.29%) males and 18(25.71%) females in this study. The mean cardioplegia volume given to Del Nido and Conventional Cardioplegia group as (1271.43 ± 447.91 vs 2142.86 ± 584.48 (ml/min) with p-value is <0.005 which shows there is a significant difference of Cardioplegia volume given to both groups. The mean cardiopulmonary bypass time (min) in Del Nido group was 116.87 ± 27.25 and in Conventional Cardioplegia group 106.58 ± 29.19 and the p-value of CPB time was significant 0.004. In our data 6(8.5%) patients from Del Nido Cardioplegia Group suffered from AKI whilst in Conventional Cardioplegia Group there were 7(10%) patients who suffered from AKI. Similarly 3(4.29%) patients from Del Nido Group and 2(2.86%) patients from conventional Cardioplegia Group previously suffered from stroke. Arrhythmia is a disorder of heart that affects the rate or rhythm at which the heart beats. Its p-value is significant (0.05) which shows there is a significant difference of this disorder in both groups Conclusion: There was a significant difference in post-operative complication Arrhythmia in both groups and the need for a lower cardioplegia volume and an uninterrupted procedure are the main advantages of Del Nido (DN) cardioplegia solution, which make it superior from conventional cardioplegia. Keywords: Coronary artery Bypass grafting surgery, Del Nido Cardioplegia, Conventional Cardioplegia, CKMB, Troponin I.

scholarly journals Association between preoperative level of hemoglobin A1c and the incidence of acute kindey injury after coronary artery bypass grafting surgery: a cohort study

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Ghada Mohamed Samir ◽  
Omar Mohamed Ali Mohamed Omar ◽  
Madiha Metwally Zidan ◽  
Hazem Abd El Rahman Fawzy ◽  
Marwa Mamdouh Mohamed El Far
Keyword(s):  
Acute Kidney Injury ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Hemoglobin A1c ◽  
Artery Bypass ◽  
Kidney Injury ◽  
P Value ◽  
Bypass Grafting ◽  
Artery Bypass Grafting

Abstract Background The development of acute kidney injury (AKI) is an important indicator of clinical outcomes after cardiac surgery. Elevated preoperative hemoglobin A1c level may be associated with acute kidney injury in patients undergoing coronary artery bypass grafting. This study will investigate the association of preoperative HbA1c levels with AKI after isolated coronary artery bypass grafting (CABG). Results Forty patients undergoing elective CABG were enrolled in this cohort study. Patients are divided into 2 equal groups who underwent isolated coronary artery bypass grafting (CABG): patients with preoperative HbA1c 5.7–6.4% (group A) (prediabetics) and patients with preoperative HbA1c > or = 6.5% (group B) (diabetics). Acute kidney injury according to the Kidney Disease: Improving Global Outcomes criteria developed in 11 patients (27.5%). There was a significant difference between the two groups as regards postoperative urinary NGAL, creatinine level on the 1st day, creatinine level on the 2nd day, urine output on the 1st day, and urine output on the 2nd day (p value was 0.001, 0.002, 0.006, 0.0002, and 0.012 respectively). Postoperative ICU stay duration was statistically significant in the diabetic group (P value 0.009). The need for renal replacement therapy was higher in the diabetic group, but it was not statistically significant between the two groups. Roc analysis shows AUC 0.922 with a significant p value (< 0.0001) and cut of value (≥ 7) with sensitivity 81.82 and specificity 93.10. Conclusion This study revealed that elevated preoperative HbA1c level above 7% showed an increase in incidence of post CABG acute kidney injury along with increase length of postoperative ICU stay.

scholarly journals Intermittent Subcutaneous Morphine for Postoperative Analgesia Following Coronary Artery Bypass Grafting

2020 ◽  
Author(s):  
CN Namitha ◽  
Manjunath R Kamath ◽  
Ananda Bangera ◽  
M Gopala Krishnan ◽  
B Amith Kiran
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Side Effects ◽  
Postoperative Pain ◽  
Coronary Artery Bypass ◽  
Postoperative Analgesia ◽  
Artery Bypass ◽  
P Value ◽  
Bypass Grafting ◽  
Artery Bypass Grafting

Introduction: An effective postoperative pain management is of utmost importance following cardiac surgery. Various agents, routes and modes are available for the treatment of postoperative pain. Subcutaneous route of administration is an easy and effective method of postoperative analgesia with improved patient satisfaction and lesser side effects compared to intravenous route. Aim: To evaluate the efficacy of Subcutaneous Morphine (SCM) as postoperative analgesia following Coronary Artery Bypass Grafting (CABG). Materials and Methods: This study was designed as a retrospective analytical survey from June 2015 to June 2017. Medical records of all patients over 18 years of age who underwent coronary artery bypass grafting were reviewed. Patients belonging to ASA PS I, II and III, patients above 18 years of age and those posted for coronary artery bypass grafting were included in the study. Patients were divided into two groups: SCM group and Paracetamol (PCT) group, depending on the primary analgesia they received. The two groups were compared using Student’s t-test for normally distributed continuous data or non-parametric tests if the data were not normally distributed. Categorical data were compared by Fisher’s-exact test. The p-values <0.05 were considered statistically significant. Results: A total of 102 records were reviewed, out of which 49 patients received SCM and 53 patients had received PCT as their primary postoperative analgesia. It was observed that PCT group required more additional analgesia (intravenous fentanyl/ tramadol) than SCM group which was statistically significant with p-value of <0.001 and the duration of Cardiac Intensive Care Unit (CICU) stay was more in PCT group with p-value of 0.001. Postoperative side effects were significantly more in PCT group. Conclusion: SCM can be effectively administered intermittently for postoperative analgesia following CABG with similar haemodynamic stability and minimal side effects as compared to intermittent intravenous PCT.

Impact of troponin I level on coronary artery bypass grafting outcomes

2020 ◽  
Vol 35 (10) ◽  
pp. 2704-2709
Author(s):  
Emma J. Morone ◽  
Shawn J. Barker ◽  
Carlos R. Martinez Licha ◽  
Lava R. Timsina ◽  
Niharika Namburi ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Troponin I ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Artery Bypass Grafting

Pericardial Cardiac Troponin I Release After Coronary Artery Bypass Grafting

1999 ◽  
Vol 89 (4) ◽  
pp. 829 ◽  
Author(s):  
Jean-Luc Fellahi ◽  
Philippe Léger ◽  
Eddy Philippe ◽  
Martine Arthaud ◽  
Bruno Riou ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Cardiac Troponin ◽  
Troponin I ◽  
Artery Bypass ◽  
Cardiac Troponin I ◽  
Bypass Grafting ◽  
Artery Bypass Grafting

Effect of nurse led education on anxiety level among coronary artery bypass grafting pre-operative patients

2020 ◽  
pp. 1-13
Author(s):  
Amjad Ali ◽  
Sarfraz Masih ◽  
Fazle Rabbi ◽  
Abdur Rasheed
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Anxiety Level ◽  
Bypass Grafting ◽  
Artery Bypass Grafting ◽  
Significant Difference ◽  
Post Assessment ◽  
Experimental Group

Abstract Objective: The objective of this study was to identify the effect of nurse-led pre-operative education in minimizing the level of anxiety among patients waiting for Coronary Artery Bypass Grafting. Methods: This experimental study was accomplished at National Institute of Cardiovascular Diseases. Out of 136, there were 80 patients identified with the presence of anxiety using AKUADS 4 to 6 weeks before CABG. Data were collected by the primary researcher from July 2016 to December 2016. Patients with anxiety were divided into experimental and non-experimental groups. After pre-operative education to the experimental group, patients from both groups were re-assessed for anxiety level one week before CABG. Result: Data were assessed through non-parametric Wilcoxon sign ranked and Mann Whitney tests. It was found that anxiety reduced significantly in post-assessment among experimental group participants. No significant difference was found for pre-anxiety assessment between experimental and non-experimental groups. It was noted that post assessment anxiety differed significantly between experimental and non-experimental groups. Conclusion: Pre-operative education was found effective to decrease level of anxiety among patients waiting for CABG. There was no significant difference between pre and post assessment among patients from non-experimental group. Key Words: CABG, Nursing Education, Patients, Anxiety. Continuous...

Pericardial Cardiac Troponin I Release After Coronary Artery Bypass Grafting

1999 ◽  
Vol 89 (4) ◽  
pp. 829 ◽  
Author(s):  
Jean-Luc Fellahi ◽  
Philippe Léger ◽  
Eddy Philippe ◽  
Martine Arthaud ◽  
Bruno Riou ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Cardiac Troponin ◽  
Troponin I ◽  
Artery Bypass ◽  
Cardiac Troponin I ◽  
Bypass Grafting ◽  
Artery Bypass Grafting

Impact of Gender on Outcome in Octogenarians after Coronary Artery Bypass Grafting

2016 ◽  
Vol 65 (04) ◽  
pp. 286-291 ◽  
Author(s):  
Bernd Panholzer ◽  
Katharina Huenges ◽  
Jill Jussli-Melchers ◽  
Felix Schoeneich ◽  
Christine Friedrich ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Extracorporeal Circulation ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Artery Bypass Grafting ◽  
The Mean ◽  
Surgery In Octogenarians ◽  
The Impact

Background Increasing life expectancy makes cardiac surgery in octogenarians not very uncommon. In this study, the impact of gender on outcome of octogenarians after coronary artery bypass grafting (CABG) was assessed. Materials and Methods We retrospectively studied 485 octogenarians (176 females: mean age 82.4 ± 2.2 years vs. 306 males: mean age 82.2 ± 2.4 years) who underwent isolated CABG using extracorporeal circulation between January 2005 and December 2012. Results No significant differences were noted between both gender groups with regard to preoperative risk factors. At baseline, the groups differed significantly with respect to mean logistic European System for Cardiac Operative Risk Evaluation (EuroSCORE) (women: 22.3 ± 17.4% vs. men: 17.5 ± 13.3%; p < 0.001). Likewise, EuroSCORE II differs significantly between women and men in our cohort (women: 16.7 ± 11.9% vs. men: 13.9 ± 10.7%; p = 0.008). Intraoperatively, the number of distal anastomoses (3.1 ± 0.9 vs. 3.2 ± 0.8), the mean extracorporeal circulation time (99 ± 31 vs. 102 ± 29 minutes), and the mean aortic cross-clamp time (63 ± 31 vs. 60 ± 19 minutes) were similar in both groups. Postoperatively, no significant differences in complications and major morbidity were observed between the groups. The 30-day mortality (women 8.0 vs. men 9.7%; p = 0.62) were without statistical significance between the groups. Conclusion Outcome of octogenarians after CABG resulted in acceptable mortality. Female gender was not associated with increased risks for morbidity and mortality after surgery. Satisfactory outcomes encourage the offering of surgery in octogenarians.

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