scholarly journals Quantitative Evaluation of Diabetic Foot Wound Healing Using Hydrogel Nanosilver Based Dressing Vs. Traditional Dressing: A Prospective Randomized Control Study

2021 ◽  
Vol 15 (6) ◽  
pp. 1571-1574
Author(s):  
Ehsan A. Yahia ◽  
Ayman E. El-Sharkawey ◽  
Magda M. Bayoumi
Keyword(s):  
Wound Healing ◽  
Diabetic Foot ◽  
Wound Dressing ◽  
Reduction Rate ◽  
Diabetic Ulcer ◽  
Randomized Control Study ◽  
The Third ◽  
Prospective Randomized Control Study ◽  
Randomized Control ◽  
Control Study

Background: The wound dressings perform a crucial role in cutaneous wounds management due to their ability to protect wounds and promote dermal and epidermal tissue regeneration. Aim:To evaluate the effectiveness of using hydrogel/nanosilver-based dressing vs. traditional dressing on diabetic foot wound healing. Methods:Sixty patients with type-2 diabetes hospitalized for diabetic foot wound treatment were recruited from selected Surgical departments. A prospective randomized control study was carried Results: The results showed that the percentage of a reduction rate of the ulcer by the third week of the treatment as in the hydrogel/nanosilver-based dressing group was higher (15.11%) than traditional wound dressing group (33.44%). Moreover, the mean ulcers size "sq mm" in the hydrogel/nanosilver-based dressing group recognized a faster healing rate (15.11±7.89), and considerably lesser in comparison to the traditional in the third week (21.65±8.4). Conclusion: The hydrogel/nanosilver-based dressing showed better results than traditional dressing in managing diabetic ulcer foot. Keywords: Diabetes, Wound Care, Diabetic Foot, Wound dressing, Hydrogel Nanosilver

scholarly journals Quantitative Evaluation of Diabetic Foot Wound Healing Using Hydrogel Composite Nanosilver (AgNPs) - Based Dressing Vs. Traditional Dressing: A Prospective Randomized Control Study

2021 ◽  
Vol 15 (6) ◽  
pp. 2043-2047
Author(s):  
Ehsan A. Yahia ◽  
Ayman E. El- Sharkawey ◽  
Magda M. Bayoumi
Keyword(s):  
Wound Healing ◽  
Diabetic Foot ◽  
Wound Dressing ◽  
Diabetic Ulcer ◽  
Nano Silver ◽  
Randomized Control Study ◽  
The Third ◽  
Prospective Randomized Control Study ◽  
Randomized Control ◽  
Control Study

Background: The wound dressings perform a crucial role in cutaneous wounds management due to their ability to protect wounds and promote dermal and epidermal tissue regeneration. Aim: the aim was to evaluate the effectiveness of using hydrogel/nano silver-based dressing vs. traditional dressing on diabetic foot wound healing. Methods: Sixty patients with type-2 diabetes hospitalized for diabetic foot wound treatment were recruited from selected Surgical departments. A prospective randomized control study was carried, and the results showed that the percentage of a reduction rate of the ulcer by the third week of the treatment as in the hydrogel/nano silver-based dressing group was higher (15.11%) than traditional wound dressing group (33.44%). Moreover, the mean ulcers size "sq mm" in the hydrogel/nano silver-based dressing group recognized a faster healing rate (15.11 ± 7.89), and considerably lesser in comparison to the traditional by the third week (21.65 ± 8.4). Conclusion: The hydrogel/nanosilver-based dressing showed better results than traditional dressing in managing diabetic ulcer foot. Keywords: Diabetes, Wound, Diabetic ulcer, Wound dressing, Nanomedicine, Nano-silver.

scholarly journals Comparison of ExPress Implantation and Partial Deep Sclerectomy Combined with ExPress Implantation and Simultaneous Phacoemulsification

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Marietta Frączkiewicz-Skok ◽  
Joanna Konopińska ◽  
Zofia Mariak ◽  
Marek Rękas
Keyword(s):  
Deep Sclerectomy ◽  
Initial Value ◽  
Randomized Control Study ◽  
Surgical Success ◽  
Prospective Randomized Control Study ◽  
Corrected Distance Visual Acuity ◽  
Randomized Control ◽  
Express Group ◽  
Control Study

Background. To compare the effectiveness and safety profile of ExPress implantation versus partial deep sclerectomy combined with ExPress implantation and simultaneous phacoemulsification. Patients and Methods. A prospective, randomized control study with 24-month follow-up was performed. 114 eyes were included, of which 42 eyes underwent phacoemulsification with simultaneous implantation of the Ex-Press device (ExPress), and deep sclerectomy with phacoemulsification and simultaneous implantation of the Ex-Press device (DS-ExPress) was performed in 72 eyes. The main outcome measures were intraocular pressure (IOP), corrected distance visual acuity (CDVA), the number of antiglaucoma medications, and the rate of complications. Surgical success was defined as complete (without antiglaucoma medications) with IOP ≤18 mmHg in criterion A, IOP ≤16 mmHg in criterion B, and IOP ≤12 mmHg in criterion C. Satisfactory success was defined as the same IOP levels for individual criteria with a maximum of 2 antiglaucoma medications. Results. Before the procedure, mean IOP in the ExPress group was 17.5 ± 4.7 mmHg; after 24 months, it decreased by 13% to 16.0 ± 3.0 mmHg (P<0.05). In the DS-ExPress group, mean IOP reduced from 16.3 ± 4.4 mmHg to 14.3 ± 3.3 mmHg (P<0.05), which was a 9% reduction compared to the initial value. In the DS-ExPress group, 65.9% of the patients did not use topical pharmacotherapy, and the same is true for 29.2% of the ExPress group (P=0.004). Conclusions. This modification is efficient in surgical treatment of glaucoma, especially when very low postoperative IOP is needed. A less amount of antiglaucoma medicines are needed.

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