Repair of post-infarction multiple anterior muscular ventricular septal defects by endocardial Dacron patch and left ventricular aneurysmectomy: a video presentation

The primary objective of this project is to design, fabricate, and test a small, integrated camera system for aiding in the visualization and surgical repair of certain types of ventricular septal defects (VSD), in pediatric patients. Currently, no purpose-designed commercial device to view VSDs from the left ventricle of the heart exists. The left ventricular perspective is ideal for obtaining an unobstructed view of the VSD. This VSD camera device would also provide a platform for passing a suture through the hole in the ventricular septum, with future work implementing additional tools capable of more advanced tasks. This camera device will help solve some of the major issues currently associated with cardiac imaging and surgical closure of VSDs in newborns and young children This paper examines the design development and preliminary evaluation of a proof of concept device. Included are preliminary results of image quality comparisons, design details of a pediatric-specific VSD camera device, and initial outcomes from in vitro testing.

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1114-204 Regression of left ventricular dilation in children with restrictive ventricular septal defects with initial large volume overload

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(04)91637-3 ◽

2004 ◽

Vol 43 (5) ◽

pp. A387

Author(s):

Mahnaz Tabibian ◽

Charles S Kleinman ◽

Thomas J Starc ◽

Beth F Printz ◽

Patrick Flynn ◽

...

Keyword(s):

Large Volume ◽

Volume Overload ◽

Left Ventricular ◽

Ventricular Septal Defects ◽

Ventricular Dilation ◽

Septal Defects ◽

Left Ventricular Dilation

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Left ventricular function in adolescents and adults with restrictive ventricular septal defect and moderate left-to-right shunting

Cardiology in the Young ◽

10.1017/s1047951100006582 ◽

2000 ◽

Vol 10 (2) ◽

pp. 126-129 ◽

Cited By ~ 7

Author(s):

Alan G. Magee ◽

Lynn Fenn ◽

Joric Vellekoop ◽

Michael J. Godman

Keyword(s):

Ventricular Septal Defect ◽

Left Ventricular Function ◽

Ventricular Function ◽

Septal Defect ◽

Systolic Function ◽

Adult Life ◽

Left Ventricular ◽

Ventricular Septal Defects ◽

Septal Defects ◽

Significant Difference

AbstractBackgroundThe long-term haemodynamic effects of a restrictive ventricular septal defect permitting moderate left-to-right shunting are not known.Patients and methodsEchocardiographic measure ments of left heart dimensions and function were compared between a group of 9 older children and adults (median age 21 years, range 12–24.5 years) having restrictive ventricular septal defects (median Qp/Qs 1.7, range 1.4–2.1) and a group of 10 age matched controls.ResultsLeft ventricular mass indexed to body surface area was significantly greater in subjects than in controls (102±29 vs. 75±13 g/m2, p=0.02), although there was no significant difference in the ratio of mass to volume. There were no significant differ ences between indexes of left ventricular systolic function. Ratios of peak early to late diastolic ventricular filling were lower in those with septal defects (1.5±0.3 vs. 1.8±0.3, p=0.013), but there were no differences in other indexes of diastolic function.ConclusionsResting left ventricular function does not appear to have deteriorated by early adult life in patients with restrictive ventricular septal defects and moderate volume loading. This would support a continued conservative approach to management in these patients.

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Left Ventricular Angiocardiography in the Study of Ventricular Septal Defects

Radiology ◽

10.1148/81.2.223 ◽

1963 ◽

Vol 81 (2) ◽

pp. 223-235 ◽

Cited By ~ 15

Author(s):

Murray G. Baron ◽

Bernard S. Wolf ◽

Leonard Steinfeld ◽

Alvin J. Gordon

Keyword(s):

Left Ventricular ◽

Ventricular Septal Defects ◽

Septal Defects

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The midterm effect of exercise capacity and quality of life in adult patients who underwent hybrid transthoracic device closure of ventricular septal defects

BMC Cardiovascular Disorders ◽

10.1186/s12872-021-02315-9 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Qiang Chen ◽

Rong Yang ◽

Yu-Qing Lei ◽

Kai-Peng Sun ◽

Hua Cao

Keyword(s):

Quality Of Life ◽

Exercise Capacity ◽

Left Ventricular ◽

Healthy People ◽

Adult Patients ◽

Ventricular Septal Defects ◽

Device Closure ◽

Septal Defects ◽

The Difference

Abstract Objective To investigate the midterm effect of exercise capacity and quality of life (QoL) of adult patients who underwent transthoracic device closure of ventricular septal defects (VSDs) and explore the gap in the quality of life and cardiopulmonary function between those patients and healthy people. Methods From January 2010 to January 2015, 58 adult patients who underwent transthoracic device closure of VSD and 60 healthy people matched for age and sex were selected and analyzed. Echocardiography and exercise capacity tests were performed, and the MOS 36-item short-form health survey (SF-36) was used to investigate the changes in QoL. Results Fifty-five patients completed the study. At the 1-year and 5-year follow-ups, the patients’ left ventricular end-systolic and end-diastolic diameters were smaller than those preoperatively, but the difference was not statistically significant. In the QoL survey, the patients’ scores after treatment showed a trend of improvement, and the improvement effect was not transient. After VSD closure, the difference in QoL between the patients and the control group was significantly reduced. However, in the exercise capacity test, the patients’ results were still worse than those of the controls. Conclusion Transthoracic device closure of VSDs is significant in improving adult patients’ QoL at the midterm follow-up, reflected in their physical and psychological fields. However, they are still unable to achieve normal levels of peak exercise ability. Therefore, further exploration and interventions are worth considering.

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