scholarly journals Preemptive analgesic efficacy of caudal ropivacaine vs bupivacaine- A randomized study in patients undergoing single level lumbar discectomy

2021 ◽  
pp. 1
Author(s):  
Gundlakunta Swathi ◽  
Kolli Chalam ◽  
Narayanam Kiran ◽  
Sunil Furtado
Keyword(s):  
Randomized Study ◽  
Analgesic Efficacy ◽  
Lumbar Discectomy ◽  
Single Level

scholarly journals ANALGESIC EFFICACY OF EPIDURAL MORPHINE AND CLONIDINEIN PATIENTS UNDERGOING DECOMPRESSION OF THE LUMBAR CANAL: A PROSPECTIVE RANDOMIZED TRIAL

2017 ◽  
Vol 16 (3) ◽  
pp. 188-192
Author(s):  
BRUNO RONCAGLIO ◽  
RAPHAEL FERNANDES CALHAU ◽  
CHARBEL JACOB JÚNIOR ◽  
IGOR MACHADO CARDOSO ◽  
JOSÉ LUCAS BATISTA JÚNIOR ◽  
...  
Keyword(s):  
Epidural Morphine ◽  
Randomized Study ◽  
Analgesic Efficacy ◽  
Control Group ◽  
Lumbar Arthrodesis ◽  
The Mean ◽  
Group 2 ◽  
Student’S T ◽  
Microsoft Office ◽  
Student’S T Test

ABSTRACT Objective: To evaluate the postoperative analgesic efficacy in patients undergoing lumbar canal decompression using epidural morphine and clonidine at the Hospital Santa Casa de Vitória - ES, Brazil. Methods: Prospective, randomized study of 60 patients with stenosis of the lumbar canal up to two levels with surgical indication, in which decompression of the canal was performed in association with lumbar arthrodesis. In group 1 we performed conventional postoperative analgesia and in group 2, in addition to conventional analgesia, we associated epidural morphine and clonidine. We used VAS as a means of analyzing pain intensity at 1, 12, and 36 hours after surgery. The statistical analysis was performed using Microsoft Office/Excel and the software GraphPad Prism (San Diego, CA, USA). Results: The mean age of patients was 47 years, and 52% were female. The mean VAS in the first hour, 12th, and 36th hours after surgery in the control group was 5.44, 2.13, and 0.55 respectively. In the morphine-clonidine group it was 6.96; 2.21 and 0.60. Comparing one group with another in its absolute values through the Mann-Whitney test, as well as comparing the pain variations between the 1st and 12th hour (1h X 12h) and between the 12th hour and 36th hour (12h x 36h ) through Student’s t test it became clear that there was no statistical difference between groups (p > 0.05). Conclusions: The addition of epidural morphine and clonidine to conventional analgesia is not beneficial to reduce postoperative pain in patients undergoing lumbar canal decompression.

90-Day Bundled Payment for Primary Single-Level Lumbar Discectomy/Decompression: What Does “Big Data” Say?

2017 ◽  
Vol 17 (10) ◽  
pp. S86
Author(s):  
Nikhil Jain ◽  
Sohrab S. Virk ◽  
Frank M. Phillips ◽  
Safdar N. Khan
Keyword(s):  
Big Data ◽  
Lumbar Discectomy ◽  
Bundled Payment ◽  
Single Level

scholarly journals The efficacy of lumbar discectomy and single-level fusion for spondylolisthesis: results from the NeuroPoint-SD registry

2013 ◽  
Vol 19 (5) ◽  
pp. 555-563 ◽  
Author(s):  
Zoher Ghogawala ◽  
Christopher I. Shaffrey ◽  
Anthony L. Asher ◽  
Robert F. Heary ◽  
Tanya Logvinenko ◽  
...  
Keyword(s):  
Disc Herniation ◽  
Patient Reported Outcome ◽  
Lumbar Discectomy ◽  
Cooperative Research ◽  
Single Level ◽  
Sf 36 ◽  
Patient Reported ◽  
Lumbar Spondylolisthesis ◽  
Level Fusion

Object There is significant practice variation and considerable uncertainty among payers and other major stakeholders as to whether many surgical treatments are effective in actual US spine practice. The aim of this study was to establish a multicenter cooperative research group and demonstrate the feasibility of developing a registry to assess the efficacy of common lumbar spinal procedures using prospectively collected patient-reported outcome measures. Methods An observational prospective cohort study was conducted at 13 US academic and community sites. Unselected patients undergoing lumbar discectomy or single-level fusion for spondylolisthesis were included. Patients completed the 36-item Short-Form Survey Instrument (SF-36), Oswestry Disability Index (ODI), and visual analog scale (VAS) questionnaires preoperatively and at 1, 3, 6, and 12 months postoperatively. Power analysis estimated a sample size of 160 patients: 125 patients with lumbar disc herniation, and 35 with lumbar spondylolisthesis. All patient data were entered into a secure Internet-based data management platform. Results Of 249 patients screened, there were 198 enrolled over 1 year. The median age of the patients was 45.0 years (49% female) for lumbar discectomy (n = 148), and 58.0 years (58% female) for lumbar spondylolisthesis (n = 50). At 30 days, 12 complications (6.1% of study population) were identified. Ten patients (6.8%) with disc herniation and 1 (2%) with spondylolisthesis required reoperation. The overall follow-up rate for the collection of patient-reported outcome data over 1 year was 88.3%. At 30 days, both lumbar discectomy and single-level fusion procedures were associated with significant improvements in ODI, VAS, and SF-36 scores (p ≤ 0.0002), which persisted over the 1-year follow-up period (p < 0.0001). By the 1-year follow-up evaluation, more than 80% of patients in each cohort who were working preoperatively had returned to work. Conclusions It is feasible to build a national spine registry for the collection of high-quality prospective data to demonstrate the effectiveness of spinal procedures in actual practice. Clinical trial registration no.: 01220921 (ClinicalTrials.gov).

Value in Single-level Lumbar Discectomy

2017 ◽  
Vol 30 (9) ◽  
pp. E1227-E1232 ◽  
Author(s):  
Benjamin P. Rosenbaum ◽  
Michael T. Modic ◽  
Ajit A. Krishnaney
Keyword(s):  
Lumbar Discectomy ◽  
Single Level

Double-Blind Comparison of Maternal Analgesia and Neonatal Neurobehaviour following Intravenous Butorphanol and Meperidine

1979 ◽  
Vol 7 (3) ◽  
pp. 224-230 ◽  
Author(s):  
Robert Hodgkinson ◽  
Robert W Huff ◽  
Robert H Hayashi ◽  
Farkhanda J Husain
Keyword(s):  
Side Effects ◽  
Severe Pain ◽  
Randomized Study ◽  
Analgesic Efficacy ◽  
Foetal Heart Rate ◽  
Efficacy And Safety ◽  
Cervical Dilation ◽  
Double Blind ◽  
Significant Difference ◽  
Blind Comparison

Butorphanol (1 mg and 2 mg) and meperidine (40 mg and 80 mg), given intravenously, were evaluated for analgesic efficacy and safety in a double-blind randomized study employing 200 consenting pre-partum patients in moderate to severe pain during the late first stage of labour. Both drugs provided adequate relief of pain to the mothers. There was no significant difference in the rate of cervical dilation, the foetal heart rate, the Apgar score, pain relief or neonatal neurobehavioural scores between those receiving butorphanol and those receiving meperidine. Twenty-two mothers who received butorphanol and eleven who received meperidine nursed their infants with no adverse effects observed. Side-effects were generally infrequent in this study; however, more side-effects were reported by the patients and observed by the investigator in the meperidine-treated cases (13%) than in the cases treated with butorphanol (2%).

scholarly journals The Pharmacokinetics and Analgesic Efficacy of Larger Dose Rectal Acetaminophen (40 mg/kg) in Adults: A Double-Blinded, Randomized Study

2000 ◽  
Vol 90 (2) ◽  
pp. 431 ◽  
Author(s):  
Dieter H. Beck ◽  
Michael R. Schenk ◽  
Kerstin Hagemann ◽  
Ulrich R. Doepfmer ◽  
Wolfgang J. Kox
Keyword(s):  
Randomized Study ◽  
Analgesic Efficacy ◽  
Double Blinded

Perioperative results following open and minimally invasive single-level lumbar discectomy

2011 ◽  
Vol 18 (12) ◽  
pp. 1667-1670 ◽  
Author(s):  
Peter Lee ◽  
John C. Liu ◽  
Richard G. Fessler
Keyword(s):  
Minimally Invasive ◽  
Lumbar Discectomy ◽  
Single Level

A Comparison of Naproxen, Indomethacin and Acetylsalicylic Acid in Pain after Varicose Vein Surgery

1978 ◽  
Vol 6 (2) ◽  
pp. 152-156 ◽  
Author(s):  
Ulla Aromaa ◽  
Kari Asp
Keyword(s):  
Side Effects ◽  
Acetylsalicylic Acid ◽  
Postoperative Analgesia ◽  
Varicose Vein ◽  
Randomized Study ◽  
Analgesic Efficacy ◽  
Varicose Vein Surgery ◽  
Double Blind ◽  
Post Operative Pain ◽  
Minor Surgery

Oral naproxen in doses of 500 mg and 750 mg daily was compared with oral indomethacin, 75 mg daily, in a double-blind, completely randomized study of patients with post-operative pain after out-patient varicose vein surgery. Altogether, 120 patients were studied. In the study 750 mg naproxen proved to be equal in respect of analgesic efficacy to 75 mg indomethacin, and it was clearly superior to 1500 mg acetylsalicylic acid. Naproxen, 500 to 750 mg daily, afforded adequate postoperative analgesia in 98% of patients. The side-effects were mild. On the basis of the study, naproxen can be recommended as a pain-relieving drug after minor surgery, particularly when an antiphlogistic effect is also desirable.

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