scholarly journals Prevention of stress-related ulcer bleeding at the intensive care unit: Risks and benefits of stress ulcer prophylaxis

2016 ◽  
Vol 5 (1) ◽  
pp. 57 ◽  
Author(s):  
Lukas Buendgens
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Stress Ulcer ◽  
Stress Ulcer Prophylaxis ◽  
Ulcer Bleeding ◽  
Risks And Benefits ◽  
Ulcer Prophylaxis

scholarly journals Implementation of Stress Ulcer Prophylaxis (SUP) in an Intensive Care Unit (ICU)

2019 ◽  
pp. 1-7
Author(s):  
Foroud Shahbazi ◽  
Hasanali Karimpur ◽  
Elham Hosseini
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Stress Ulcer ◽  
Tertiary Hospital ◽  
Stress Ulcer Prophylaxis ◽  
Ulcer Bleeding ◽  
Cross Sectional ◽  
Ulcer Prophylaxis

Background: Critically ill patients are at high risk for developing stress ulcer bleeding, which may increase the length of hospitalization and mortality rate. Stress ulcer prophylaxis could be done either with PPIs or with H2 receptor blockers, which were prescribed in critically ill patients. Aim: This cross-sectional study was accomplished in an intensive care unit to implement new stress ulcer prophylaxis.  Methods: This study was conducted in a tertiary hospital of Kermanshah province, west of Iran. Patients who were hospitalized for at least 72 hours and received SUP prophylaxis, were included in our study. Updated ASHP guideline was used for calculating SUP risk score. Patients received either PPIs or H2RA (intravenously or enteral). Efficacy and safety of early changes to enteral route were evaluated in one year and cost was calculated in three years’ period.  Results: This study was conducted on 150 patients with a mean age of 58 ± 18 years old. More than half of patients (53.3%) were male. Stress ulcer prophylaxis was prescribed for all critically ill patients, regardless of the risk of GI bleeding while only 76.6% of patients had an appropriate indication for receiving SUP protocol. Six patients in the PPIs group (4 in intravenous and 2 in enteral) experienced gastrointestinal bleeding. Changing the route of administration from intravenous to intravenous over a three-year period resulted in a decrease in the mean use of pentoprazole vials from 12 to 4 per patient. Conclusion: Early changing (within 72 hours) SUP from IV to enteral is safe and cost-saving approach.

scholarly journals Adequacy of stress ulcer prophylaxis prescription in the intensive care unit: an observational study

2020 ◽  
Author(s):  
Marilena Franchitti ◽  
Jitka Piubellini ◽  
Farshid Sadeghipour ◽  
Philippe Eckert ◽  
Pierre Voirol ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Observational Study ◽  
Stress Ulcer ◽  
Stress Ulcer Prophylaxis ◽  
Ulcer Prophylaxis

Stress ulcer prophylaxis in adult intensive care unit patients - a protocol for a systematic review

2018 ◽  
Vol 62 (6) ◽  
pp. 744-755 ◽  
Author(s):  
M. Barbateskovic ◽  
S. Marker ◽  
J. C. Jakobsen ◽  
M. Krag ◽  
A. Granholm ◽  
...  
Keyword(s):  
Systematic Review ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Stress Ulcer ◽  
Stress Ulcer Prophylaxis ◽  
Adult Intensive Care Unit ◽  
Ulcer Prophylaxis

FACTORS AFFECTING THE OVERUSE OF STRESS ULCER PROPHYLAXIS IN PATIENTS IN THE INTENSIVE CARE UNIT

CHEST Journal ◽  
2007 ◽  
Vol 132 (4) ◽  
pp. 564A
Author(s):  
William W. Hope ◽  
Thomas Schmelzer ◽  
Aram Kim ◽  
Jonathan Salashour ◽  
M.C. Barrett ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Stress Ulcer ◽  
Stress Ulcer Prophylaxis ◽  
Factors Affecting ◽  
Ulcer Prophylaxis

scholarly journals INTENSIVE CARE UNIT PRESCRIPTIONS MUST FIT RISK FACTORS TO PREVENT STRESS ULCER BLEEDING

2021 ◽  
Vol 34 (3) ◽  
Author(s):  
Rodolfo Castro Cesar de OLIVEIRA ◽  
Osvaldo MALAFAIA ◽  
Fernando Issamu TABUSHI ◽  
Carlos Roberto NAUFEL JUNIOR ◽  
Elora Sampaio LOURENCO ◽  
...  
Keyword(s):  
Risk Factors ◽  
Spinal Cord ◽  
Intensive Care ◽  
Stress Ulcer ◽  
Stress Ulcer Prophylaxis ◽  
Ulcer Bleeding ◽  
Digestive Bleeding ◽  
Cord Injury ◽  
Ulcer Prophylaxis ◽  
Stress Ulcer Bleeding

ABSTRACT Background: The physiological stress of critically ill patients can trigger several complications, including digestive bleeding due to stress ulcers (DBSU). The use of acid secretion suppressants to reduce their incidence has become widely used, but with the current understanding of the risks of these drugs, their use, as prophylaxis in critically ill patients, is limited to the patients with established risk factors. Aim: To determine the appropriateness of the use of prophylaxis for stress ulcer bleeding in acutely ill patients admitted to intensive care units and to analyze the association of risk factors with adherence to the prophylaxis guideline. Methods: Retrospective, analytical study carried out in three general adult intensive care units. Electronic medical records were analyzed for epidemiological data, risk factors for DBSU, use of stress ulcer prophylaxis, occurrence of any digestive bleeding and confirmed DBSU. The daily analysis of risk factors and prophylaxis use were in accordance with criteria based on the Guidelines of the Portuguese Society of Intensive Care for stress ulcer prophylaxis. Results: One hundred and five patients were included. Of the patient days with the opportunity to prescribe prophylaxis, compliance was observed in 95.1%. Of the prescription days, 82.35% were considered to be of appropriate use. Overt digestive bleeding occurred in 3.81% of those included. The occurrence of confirmed DBSU was identified at 0.95%. Multivariate analysis by logistic regression did not identify risk factors independently associated with adherence to the guideline, but identified risk factors with a negative association, which were spinal cord injury (OR 0.02 p <0.01) and shock (OR 0.36 p=0.024). Conclusion: The present study showed a high rate of adherence to stress ulcer prophylaxis, but with inappropriate use still significant. In the indication of prophylaxis, attention should be paid to patients with spinal cord injury and in shock.

Sign in / Sign up

Export Citation Format

Share Document