scholarly journals Obstructive sleep apnea syndrome and cardiovascular disease: The influence of C-reactive protein

2015 ◽  
Vol 5 (2) ◽  
pp. 77 ◽  
Author(s):  
Izolde Bouloukaki
Keyword(s):  
Cardiovascular Disease ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Obstructive Sleep ◽  
Apnea Syndrome

Patients with severe obstructive sleep apnea syndrome and elevated high-sensitivity C-reactive protein need priority treatment

2010 ◽  
Vol 143 (1) ◽  
pp. 72-77 ◽  
Author(s):  
Li-Ang Lee ◽  
Ning-Hung Chen ◽  
Chung-Guei Huang ◽  
Shih-Wei Lin ◽  
Tuan-Jen Fang ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
High Sensitivity ◽  
Severe Obstructive Sleep Apnea ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Obstructive Sleep ◽  
Apnea Syndrome

scholarly journals Endothelial Dysfunction and C-Reactive Protein in Relation with the Severity of Obstructive Sleep Apnea Syndrome

SLEEP ◽  
2007 ◽  
Vol 30 (8) ◽  
pp. 997-1001 ◽  
Author(s):  
Seockhoon Chung ◽  
In-Young Yoon ◽  
Yoon-Kyung Shin ◽  
Chul Hee Lee ◽  
Jeong-Whun Kim ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Endothelial Dysfunction ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Obstructive Sleep ◽  
Apnea Syndrome

scholarly journals Elevated C-Reactive Protein Levels and Increased Cardiovascular Risk in Patients With Obstructive Sleep Apnea Syndrome

2005 ◽  
Vol 46 (5) ◽  
pp. 801-809 ◽  
Author(s):  
Oguz Kokturk ◽  
Tansu Ulukavak Ciftci ◽  
Elif Mollarecep ◽  
Bulent Ciftci
Keyword(s):  
Obstructive Sleep Apnea ◽  
Cardiovascular Risk ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Obstructive Sleep ◽  
Apnea Syndrome

Uvulopalatopharyngoplasty decreases levels of C-reactive protein in patients with obstructive sleep apnea syndrome

2006 ◽  
Vol 152 (4) ◽  
pp. 692.e1-692.e5 ◽  
Author(s):  
Hiroyuki Kinoshita ◽  
Akira Shibano ◽  
Takema Sakoda ◽  
Hiroki Ikeda ◽  
Hiroshi Iranami ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Obstructive Sleep ◽  
Apnea Syndrome

Severity of Obstructive Sleep Apnea Syndrome and High-Sensitivity C-Reactive Protein Reduced After Relocation Pharyngoplasty

2011 ◽  
Vol 144 (4) ◽  
pp. 632-638 ◽  
Author(s):  
Li-Ang Lee ◽  
Chung-Guei Huang ◽  
Ning-Hung Chen ◽  
Chun-Li Wang ◽  
Tuan-Jen Fang ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Obstructive Sleep ◽  
Apnea Syndrome

Cardiovascular outcomes of CPAP therapy in obstructive sleep apnea syndrome

2007 ◽  
Vol 293 (4) ◽  
pp. R1666-R1670 ◽  
Author(s):  
Walter T. McNicholas
Keyword(s):  
Cardiovascular Disease ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Cpap Therapy ◽  
Obstructive Sleep ◽  
Cardiovascular Morbidity And Mortality ◽  
Apnea Syndrome ◽  
The Impact

Considerable evidence is now available of an independent association between obstructive sleep apnea syndrome (OSAS) and cardiovascular disease. The association is particularly strong for systemic arterial hypertension, but there is growing evidence of an association with ischemic heart disease and stroke. The mechanisms underlying cardiovascular disease in patients with OSAS are still poorly understood. However, the pathogenesis is likely to be a multifactorial process involving a diverse range of mechanisms, including sympathetic overactivity, selective activation of inflammatory molecular pathways, endothelial dysfunction, abnormal coagulation, and metabolic dysregulation, the latter particularly involving insulin resistance and disordered lipid metabolism. Therapy with continuous positive airway pressure (CPAP) has been associated with significant benefits to cardiovascular morbidity and mortality, both in short-term studies addressing specific aspects of morbidity, such as hypertension, and more recently in long-term studies that have evaluated major outcomes of cardiovascular morbidity and mortality. However, there is a clear need for further studies evaluating the impact of CPAP therapy on cardiovascular outcomes. Furthermore, studies on the impact of CPAP therapy have provided useful information concerning the role of basic cell and molecular mechanisms in the pathophysiology of OSAS.

scholarly journals Association of subclinical inflammation, glycated hemoglobin and risk for obstructive sleep apnea syndrome

2017 ◽  
Vol 15 (2) ◽  
pp. 136-140
Author(s):  
Carolina Vicaria Rodrigues D’Aurea ◽  
Bruno Gion de Andrade Cerazi ◽  
Antonio Gabriele Laurinavicius ◽  
Carolina Castro Porto Silva Janovsky ◽  
Raquel Dilguerian de Oliveira Conceição ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Glycated Hemoglobin ◽  
Sleep Apnea Syndrome ◽  
High Sensitivity ◽  
Berlin Questionnaire ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Obstructive Sleep

ABSTRACT Objective To investigate the inter-relation between high sensitivity C-reactive protein and glycated hemoglobin in prediction of risk of obstructive sleep apnea. Methods We included all individuals participating in a check-up program at the Preventive Medicine Center of Hospital Israelita Albert Einstein in 2014. The Berlin questionnaire for risk of obstructive sleep apnea was used, and the high sensitivity C-reactive protein and glycated hemoglobin levels were evaluated. Results The sample included 7,115 participants (age 43.4±9.6 years, 24.4% women). The Berlin questionnaire showed changes in 434 (6.1%) individuals. This finding was associated with high sensitivity C-reactive protein and glycated hemoglobin levels (p<0.001). However, only the association between the Berlin questionnaire result and glycated hemoglobin remained significant in the adjusted multivariate analysis, for the traditional risk factors and for an additional model, including high-density lipoprotein cholesterol and triglycerides. Conclusion The glycated hemoglobin, even below the threshold for diagnosis of diabetes, is independently associated with obstructive sleep apnea syndrome, even after adjustment for obesity and C-reactive protein. These findings suggest a possible pathophysiological link between changes in insulin resistance and obstructive sleep apnea syndrome, independently from obesity or low-grade inflammation.

Sign in / Sign up

Export Citation Format

Share Document