Optimal Vaccination of an Endemic Model with Variable Infectivity and Infinite Delay

2013 ◽  
Vol 68 (10-11) ◽  
pp. 677-685 ◽  
Author(s):  
Gul Zaman ◽  
Yasuhisa Saito ◽  
Madad Khan
Keyword(s):  
Optimal Control ◽  
Control Problem ◽  
Control Function ◽  
Control Strategies ◽  
Infinite Delay ◽  
Nonlinear Differential Equations ◽  
Infected Individual ◽  
Vaccination Schedule ◽  
Disease Evolution ◽  
Spread Of Infection

In this work, we consider a nonlinear SEIR (susceptible, exposed, infectious, and removed) endemic model, which describes the dynamics of the interaction between susceptible and infected individuals in a population. The model represents the disease evolution through a system of nonlinear differential equations with variable infectivity which determines that the infectivity of an infected individual may not be constant during the time after infection. To control the spread of infection and to find a vaccination schedule for an endemic situation, we use optimal control strategies which reduce the susceptible, exposed, and infected individuals and increase the total number of recovered individuals. In order to do this, we introduce the optimal control problem with a suitable control function using an objective functional. We first show the existence of an optimal control for the control problem and then derive the optimality system. Finally the numerical simulations of the model is identified to fit realistic measurement which shows the effectiveness of the model.

Dynamics Response Control of a Mindlin-Type Beam

2017 ◽  
Vol 17 (03) ◽  
pp. 1750039 ◽  
Author(s):  
Kenan Yildirim ◽  
Seda G. Korpeoglu ◽  
Ismail Kucuk
Keyword(s):  
Optimal Control ◽  
Partial Differential Equations ◽  
Maximum Principle ◽  
Control Problem ◽  
Control Function ◽  
Initial Boundary ◽  
Response Control ◽  
Adjoint Variables ◽  
Dynamics Response ◽  
Optimal Control Function

Optimal boundary control for damping the vibrations in a Mindlin-type beam is considered. Wellposedness and controllability of the system are investigated. A maximum principle is introduced and optimal control function is obtained by means of maximum principle. Also, by using maximum principle, control problem is reduced to solving a system of partial differential equations including state, adjoint variables, which are subject to initial, boundary and terminal conditions. The solution of the system is obtained by using MATLAB. Numerical results are presented in table and graphical forms.

On an optimal control problem with an integral functional of a rational control function

2009 ◽  
Vol 45 (11) ◽  
pp. 1621-1635 ◽  
Author(s):  
N. L. Grigorenko ◽  
D. V. Kamzolkin ◽  
L. N. Luk’yanova ◽  
D. G. Pivovarchuk
Keyword(s):  
Optimal Control ◽  
Optimal Control Problem ◽  
Control Problem ◽  
Control Function ◽  
Integral Functional ◽  
Rational Control

scholarly journals Optimal Control of HIV/AIDS in the Workplace in the Presence of Careless Individuals

2014 ◽  
Vol 2014 ◽  
pp. 1-19 ◽  
Author(s):  
Baba Seidu ◽  
Oluwole D. Makinde
Keyword(s):  
Optimal Control ◽  
Optimal Control Problem ◽  
Control Problem ◽  
Control Strategies ◽  
Nonlinear Dynamical System ◽  
Basic Reproductive Number ◽  
Reproductive Number ◽  
Nonlinear Dynamical ◽  
Basic Model ◽  
Hiv Aids

A nonlinear dynamical system is proposed and qualitatively analyzed to study the dynamics of HIV/AIDS in the workplace. The disease-free equilibrium point of the model is shown to be locally asymptotically stable if the basic reproductive number,R0, is less than unity and the model is shown to exhibit a unique endemic equilibrium when the basic reproductive number is greater than unity. It is shown that, in the absence of recruitment of infectives, the disease is eradicated whenR0<1, whiles the disease is shown to persist in the presence of recruitment of infected persons. The basic model is extended to include control efforts aimed at reducing infection, irresponsibility, and nonproductivity at the workplace. This leads to an optimal control problem which is qualitatively analyzed using Pontryagin’s Maximum Principle (PMP). Numerical simulation of the resulting optimal control problem is carried out to gain quantitative insights into the implications of the model. The simulation reveals that a multifaceted approach to the fight against the disease is more effective than single control strategies.

scholarly journals On the Regularized Solutions of Optimal Control Problem in a Hyperbolic System

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Yeşim Saraç ◽  
Murat Subaşı
Keyword(s):  
Optimal Control ◽  
Control Problem ◽  
Iterative Procedure ◽  
Control Function ◽  
Optimal Solution ◽  
Test Problems ◽  
Initial Condition ◽  
Final Time ◽  
State Variable ◽  
Suitable Norm

We use the initial condition on the state variable of a hyperbolic problem as control function and formulate a control problem whose solution implies the minimization at the final time of the distance measured in a suitable norm between the solution of the problem and given targets. We prove the existence and the uniqueness of the optimal solution and establish the optimality condition. An iterative algorithm is constructed to compute the required optimal control as limit of a suitable subsequence of controls. An iterative procedure is implemented and used to numerically solve some test problems.

Solving the Problem of the Optimal Control System General Synthesis Based on Approximation of a Set of Extremals using the Symbol Regression Method

2020 ◽  
pp. 59-74
Author(s):  
S.V. Konstantinov ◽  
A.I. Diveev
Keyword(s):  
Optimal Control ◽  
Control System ◽  
Optimal Control Problem ◽  
Control Problem ◽  
Control Function ◽  
Symbolic Regression ◽  
Regression Method ◽  
Synthesis Problem ◽  
Optimal Control System ◽  
Initial States

A new approach is considered to solving the problem of synthesizing an optimal control system based on the extremals' set approximation. At the first stage, the optimal control problem for various initial states out of a given domain is being numerically sold. Evolutionary algorithms are used to solve the optimal control problem numerically. At the second stage, the problem of approximating the found set of extremals by the method of symbolic regression is solved. Approach considered in the work makes it possible to eliminate the main drawback of the known approach to solving the control synthesis problem using the symbolic regression method, which consists in the fact that the genetic algorithm used in solving the synthesis problem does not provide information about proximity of the found solution to the optimal one. Here, control function is built on the basis of a set of extremals; therefore, any particular solution should be close to the optimal trajectory. Computational experiment is presented for solving the applied problem of synthesizing the four-wheel robot optimal control system in the presence of phase constraints. It is experimentally demonstrated that the synthesized control function makes it possible for any initial state from a given domain to obtain trajectories close to optimal in the quality functional. Initial states were considered during the experiment, both included in the approximating set of optimal trajectories and others from the same given domain. Approximation of the extremals set was carried out by the network operator method

scholarly journals A nonlinear plate control without linearization

2017 ◽  
Vol 15 (1) ◽  
pp. 179-186
Author(s):  
Kenan Yildirim ◽  
Ismail Kucuk
Keyword(s):  
Optimal Control ◽  
Nonlinear Systems ◽  
Control Problem ◽  
Performance Index ◽  
Control Function ◽  
Initial Boundary ◽  
Quadratic Functional ◽  
Penalty Term ◽  
Nonlinear Plate ◽  
Optimal Control Function

Abstract In this paper, an optimal vibration control problem for a nonlinear plate is considered. In order to obtain the optimal control function, wellposedness and controllability of the nonlinear system is investigated. The performance index functional of the system, to be minimized by minimum level of control, is chosen as the sum of the quadratic 10 functional of the displacement. The velocity of the plate and quadratic functional of the control function is added to the performance index functional as a penalty term. By using a maximum principle, the nonlinear control problem is transformed to solving a system of partial differential equations including state and adjoint variables linked by initial-boundary-terminal conditions. Hence, it is shown that optimal control of the nonlinear systems can be obtained without linearization of the nonlinear term and optimal control function can be obtained analytically for nonlinear systems without linearization.

Optimal Control Problem with an Integral Functional of an Exponential Control Function

2014 ◽  
Vol 26 (1) ◽  
pp. 1-13 ◽  
Author(s):  
N. L. Grigorenko ◽  
D. V. Kamzolkin ◽  
L. N. Luk’yanova ◽  
D. G. Pivovarchuk
Keyword(s):  
Optimal Control ◽  
Optimal Control Problem ◽  
Control Problem ◽  
Control Function ◽  
Integral Functional

scholarly journals Optimal Control Problem for Cholera Disease and Cost-Effectiveness Analysis

2021 ◽  
Vol 53 (2) ◽  
pp. 200-2017
Author(s):  
Jhoana Patricia Romero-Leiton ◽  
Muhammad Ozair ◽  
Takasar Hussaing
Keyword(s):  
Optimal Control ◽  
Cost Effectiveness ◽  
Optimal Control Problem ◽  
Control Problem ◽  
Control Strategies ◽  
Cost Effectiveness Analysis ◽  
Effectiveness Analysis ◽  
Using Data ◽  
Theoretical Results

Cholera is a disease that continues to be a threat to public health globally and is an indicator of inequity and lack of social development in countries. For this reason, strategies for its control need to be investigated. In this work, an optimal control problem related to cholera disease was formulated by introducing personal protection, drug treatment and water sanitation as control strategies. First, the existence and characterization of controls to minimize the performance index or cost function was proved by using classic control theory. Then, the theoretical results were validated with numerical experiments by using data reported in the literature. Finally, the effectiveness and efficiency of the proposed controls were determined through a cost-effectiveness analysis. The results showed that the use of the three controls simultaneously is the cheapest and most effective strategy to control the disease.

scholarly journals Optimization of spatial control strategies for population replacement, application to Wolbachia

2021 ◽  
Author(s):  
Yannick Privat ◽  
Michel Duprez ◽  
Nicolas Vauchelet ◽  
Romane Hélie
Keyword(s):  
Optimal Control ◽  
Optimal Control Problem ◽  
Control Problem ◽  
Control Strategies ◽  
Mosquito Population ◽  
Infected Mosquito ◽  
Asymptotic Model ◽  
Population Replacement ◽  
Replacement Technique ◽  
Very High

In this article, we are interested in the analysis and simulation of solutions to an optimal control problem motivated by population dynamics issues. In order to control the spread of mosquito-borne arboviruses, the population replacement technique consists in releasing into the environment mosquitoes infected with the Wolbachia bacterium, which greatly reduces the trans- mission of the virus to the humans. Spatial releases are then sought in such a way that the infected mosquito population invades the uninfected mosquito population. Assuming very high mosquito fecundity rates, we first introduce an asymptotic model on the proportion of infected mosquitoes and then an optimal control problem to determine the best spatial strategy to achieve these releases. We then analyze this problem, including the optimality of natural candidates and carry out first numerical simulations in one dimension of space to illustrate the relevance of our approach.

scholarly journals Modeling and Control of the Public Opinion: An Agree-Disagree Opinion Model

2020 ◽  
Vol 2020 ◽  
pp. 1-15
Author(s):  
Sara Bidah ◽  
Omar Zakary ◽  
Mostafa Rachik
Keyword(s):  
Optimal Control ◽  
Control Problem ◽  
Initial Conditions ◽  
Control Strategies ◽  
Rank Correlation ◽  
Latin Hypercube Sampling ◽  
Optimal Controls ◽  
Modeling And Control ◽  
Partial Rank Correlation ◽  
Objective Functional

In this paper, we aim to investigate optimal control to a new mathematical model that describes agree-disagree opinions during polls, which we presented and analyzed in Bidah et al., 2020. We first present the model and recall its different compartments. We formulate the optimal control problem by supplementing our model with a objective functional. Optimal control strategies are proposed to reduce the number of disagreeing people and the cost of interventions. We prove the existence of solutions to the control problem, we employ Pontryagin’s maximum principle to find the necessary conditions for the existence of the optimal controls, and Runge–Kutta forward-backward sweep numerical approximation method is used to solve the optimal control system, and we perform numerical simulations using various initial conditions and parameters to investigate several scenarios. Finally, a global sensitivity analysis is carried out based on the partial rank correlation coefficient method and the Latin hypercube sampling to study the influence of various parameters on the objective functional and to identify the most influential parameters.

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