Sub-lethal Effect of Pesticides on the Distribution of Glutaminases in the Brain of Labeo rohita (Ham.)

10.5580/18c0 ◽  
2010 ◽  
Vol 7 (2) ◽  
Keyword(s):  
2009 ◽  
Vol 91 (1) ◽  
pp. 118-124 ◽  
Author(s):  
PL.RM. Palaniappan ◽  
V. Vijayasundaram
Keyword(s):  
Ft Ir ◽  
Ir Study ◽  

1932 ◽  
Vol 55 (2) ◽  
pp. 223-234 ◽  
Author(s):  
Hugh K. Ward ◽  
Joyce Wright

1. An acute purulent meningitis due to the invasion of the meninges by Pfeiffer's influenza bacillus is not a very uncommon disease ininfants and young children. It has a very high mortality. 2. Complement is entirely absent in the cerebrospinal fluid of these cases, and bactericidal experiments suggest that the injection of a specific antiserum will have but slight lethal effect on the organisms unless complement is injected at the same time. 3. Treatment with a mixture of specific antiserum and complement led in some cases to a definite clinical improvement, coincident with sterilization and clearing of the cerebrospinal fluid. But after some days, the patients relapsed and died. Autopsy showed localized abscesses in the vicinity of the base of the brain, the lesions being definitely walled off from the general subarachnoid space. In one case, the patient recovered. 4. Since the walls of the abscesses apparently present an insuperable mechanical obstacle to the action of the antiserum and complement, the possibility of preventing the formation of abscesses is discussed. Earlier diagnosis and more rapid sterilization are the most obvious measures. Bactericidal experiments indicate that the proportion of antiserum to complement may be an important factor in bringing about a more rapid elimination of the bacilli.


2010 ◽  
Vol 216 (1) ◽  
pp. 67-75 ◽  
Author(s):  
Nikhil V. Palande ◽  
Saikat Biswas ◽  
Arun G. Jadhao
Keyword(s):  

2001 ◽  
Vol 29 (6) ◽  
pp. 812-817 ◽  
Author(s):  
D. Richard ◽  
S. Clavel ◽  
Q. Huang ◽  
D. Sanchis ◽  
D. Ricquier

Uncoupling protein 2 (UCP2) mRNA is expressed in a panoply of tissues, including the brain, where it is widely distributed. In the mouse brain, it is expressed in the hypothalamus (suprachiasmatic, paraventricular, dorsomedial, ventromedial and arcuate nuclei), the thalamus (submedius nucleus) and the brain-stem (dorsal motor nucleus of the vagus nerve). In the rat brain, it is also expressed in the hippocampus. The presence of UCP2 mRNA in neurons expressing corticotropin-re-leasing factor and arginine-vasopressin suggests a role for UCP2 in the control of neuroendocrine and behavioural functions. We have recently demonstrated that UCP2-deficient mice can resist the lethal effect of toxoplasmosis through an enhanced production of reactive oxygen species (ROS) from the macrophages. This finding provides evidence that UCP2 can be part of a mechanism preventing ROS production. UCP2 could therefore be involved in protecting the brain against oxidative stress. The involvement of UCP2 in neuroprotection is also consistent with the recent observation that kainic acid, which promotes Ca2+ uptake in the glutamate-activated neurons in the hippocampal CA1 field, can induce the UCP2 gene in the activated CA1 cells. The role of UCP2 in neuroprotection warrants further investigation.


2020 ◽  
Author(s):  
Evan K. Noch ◽  
Isaiah Yim ◽  
Teresa A. Milner ◽  
Lewis C. Cantley
Keyword(s):  

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