scholarly journals Glaucoma medication non-compliance in Hebron, Palestine

2021 ◽  
Vol 6 (0) ◽  
pp. 10-16
Author(s):  
Riyad Banayot
Keyword(s):  
2013 ◽  
Vol 90 (8) ◽  
pp. 883-897 ◽  
Author(s):  
Laura E. Dreer ◽  
Christopher A. Girkin ◽  
Lisa Campbell ◽  
Andy Wood ◽  
Liyan Gao ◽  
...  

2009 ◽  
Vol 87 (4) ◽  
pp. 468-469 ◽  
Author(s):  
Kaweh Mansouri ◽  
Tarek Shaarawy
Keyword(s):  

2009 ◽  
Vol 87 (4) ◽  
pp. 469-471 ◽  
Author(s):  
Juliette G.M.M. Hoevenaars ◽  
Jan S.A.G. Schouten ◽  
Bart van den Borne ◽  
Henny J.M. Beckers ◽  
Carroll A.B. Webers
Keyword(s):  

2011 ◽  
Vol 20 (9) ◽  
pp. 573-576 ◽  
Author(s):  
Salman J. Yousuf ◽  
Leslie S. Jones
Keyword(s):  

2019 ◽  
Vol 556 ◽  
pp. 192-199 ◽  
Author(s):  
Rania M. Hathout ◽  
Heba A. Gad ◽  
Salma M. Abdel-Hafez ◽  
Nayera Nasser ◽  
Noha Khalil ◽  
...  

2013 ◽  
Vol 28 (3) ◽  
pp. 191-201 ◽  
Author(s):  
Paula Anne Newman-Casey ◽  
Jennifer S. Weizer ◽  
Michele Heisler ◽  
Paul P. Lee ◽  
Joshua D. Stein

2018 ◽  
Vol 102 (11) ◽  
pp. 1497-1503 ◽  
Author(s):  
David W Steven ◽  
Pouya Alaghband ◽  
Kin Sheng Lim

Preservatives continue to be in widespread use in ophthalmic medications due to the convenience they provide, regulatory requirements and the higher cost of alternatives. Benzalkonium chloride (BAK) remains the most commonly used preservative but there is a trend towards the use of preservative-free (PF) drops for glaucoma, although at a higher price. An extensive body of literature explores BAK toxicity on ocular structures in animal and laboratory studies (in vitro and in vivo). Non-randomised controlled studies have provided some supporting evidence of its toxicity in patients, especially in those with pre-existing ocular surface disease (OSD) or on multiple medications. However, there have been very few randomised controlled trials that compare the same medication with and without BAK preservative. Several of these trials have never been published in any peer reviewed journals. Notwithstanding, those that have been published, have not demonstrated any clear benefits of the BAK-free formulations. Short duration and exclusion of those with OSD are limitations of these studies. There is a lack of evidence of clinically significant harm from a small number of BAK preserved drops in patients without OSD. This means that generally more expensive PF glaucoma medications should only be recommended for those on poly pharmacy or those with OSD but are not necessarily required for all patients.


2018 ◽  
Vol 102 (12) ◽  
pp. 1667-1671 ◽  
Author(s):  
Jonathan Y-X L Than ◽  
Toby S Al-Mugheiry ◽  
Jesse Gale ◽  
Keith R Martin

BackgroundBleb needling is widely used to restore flow and lower intraocular pressure (IOP) in a failing trabeculectomy. We aimed to measure the safety and efficacy of needling in a large cohort and identify factors that were associated with success and failure.MethodsThis retrospective audit included all patients who underwent needling at Addenbrooke’s Hospital, Cambridge over a 10-year period. Data were available on 91 patients (98% of patients identified), including 191 needlings on 96 eyes. Success was defined as IOP below 21 mm Hg or 16 mm Hg or 13 mm Hg consistently, without reoperation or glaucoma medication. Risk factors for failure were assessed by Cox proportional hazard regression and Kaplan-Meier curves.ResultsSuccess defined as IOP <16 mm Hg was 66.6% at 12 months and 53% at 3 years and success defined as IOP <21 mm Hg was 77.1% at 12 months and 73.1% at 3 years. Failure after needling was most common in the first 6 months. Factors that predicted failure were flat or fibrotic blebs (non-functional) and no longer injected, while success was predicted by achieving a low IOP immediately after needling. No significant complications were identified.ConclusionNeedling was most successful soon after trabeculectomy, but resuscitation of a long-failed trabeculectomy had lower likelihood of success. The safety and efficacy compare favourably with alternative treatment approaches.


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