Successful hemihepatectomy following chemotherapy for primary liver lymphoma: case report and review of literature

2017 ◽  
Vol 89 (5) ◽  
pp. 54-58 ◽  
Author(s):  
Aleksander Skulimowski ◽  
Piotr Hogendorf ◽  
Grażyna Poznańska ◽  
Piotr Smolewski ◽  
Janusz Strzelczyk ◽  
...  

Non-Hodgkin lymphomas (NHL) comprise a heterogeneous group of B-cell and T-cell neoplasms. Diffuse large B-cell lymphoma (DLBCL), the most common type of NHL, accounts for around 30-40% of NHL cases. However, primary hepatic location of NHLs is rare and constitutes 0.01% of all NHL cases. Due to this rarity and a lack of large randomized trails, it is still unclear what treatment should be used for primary hepatic DLBCLs. In this study, we report of a female patient with primary hepatic DLBCL who was successfully treated with neoadjuvant chemotherapy and surgery. We also shortly review the literature regarding surgical treatments for primary GI tract NHLs. Taking into account our experience and the current literature, surgical treatment with postoperative chemotherapy seems to be a feasible option for patients with focal primary hepatic DLBCLs.

2018 ◽  
Vol 6 (6) ◽  
pp. 121-126
Author(s):  
Chapman Wei ◽  
Chaplin Wei ◽  
Omar Alhalabi ◽  
Lei Chen

2017 ◽  
Vol 126 (5) ◽  
pp. 1725-1730 ◽  
Author(s):  
Vijay M. Ravindra ◽  
Amol Raheja ◽  
Heather Corn ◽  
Meghan Driscoll ◽  
Corrine Welt ◽  
...  

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma and comprises approximately 30% of all lymphomas. Patients typically present with a nonpainful mass in the neck, groin, or abdomen associated with constitutional symptoms. In this report, however, the authors describe a rare case of a 61-year-old woman with hyperprolactinemia, hypothyroidism, and acromegaly (elevation of insulin-like growth factor-1 [IGF-1]) with elevated growth hormone–releasing hormone (GHRH) in whom an MRI demonstrated diffuse enlargement of the pituitary gland. Despite medical treatment, the patient had persistent elevation of IGF-1. She underwent a transsphenoidal biopsy, which yielded a diagnosis of DLBCL with an activated B-cell immunophenotype with somatotroph hyperplasia. After stereo-tactic radiation therapy in combination with chemotherapy, she is currently in remission from her lymphoma and has normalized IGF-1 levels without medical therapy, 8 months after her histopathological diagnosis. This is the only reported case of its kind and displays the importance of a broad differential diagnosis, multidisciplinary evaluation, and critical intraoperative decision-making when treating atypical sellar lesions.


2014 ◽  
Vol 6 (3) ◽  
pp. 231 ◽  
Author(s):  
Vishwanath Sathyanarayanan ◽  
TM Suresh ◽  
Lokanatha Dasappa ◽  
Govinda BabuK Kanakasetty ◽  
CLakshmaiah Kuntegowdanahalli ◽  
...  

Author(s):  
Soheila Aminimoghaddam ◽  
Elnaz Salarifar ◽  
Somayyeh Noei Teymoordash

Abstract The primary diffuse large B cell lymphoma (DLBCL) of the uterine cervix is extremely rare. In the present study, we described two cases of DLBCL of the uterine cervix in reproductive-aged women complaining of postcoital bleeding, recurrent vaginal discharge, and abnormal uterine bleeding.


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