Are children with asthma in South Korea also associated with vitamin D deficiency?

Background: Vitamin D deficiency has been rediscovered as a public health problem worldwide. Few studies have shown that vitamin D deficiency is associated with asthma severity. The objective of present work was to study the serum vitamin D levels and its relationship with asthma severity in children.Methods: A prospective cohort study of 100 children with asthma between the age group of 5 to 15 years and age and sex matched 40 healthy controls who had come to Indira Gandhi Institute of Child Health, Bengaluru was done. These children’s serum vitamin D levels were estimated and correlated with asthma severity.Results: A total of 100 children with asthma and 40 healthy age and sex matched controls were evaluated. The study group had lower vitamin D (34.95 ng/ml) levels as compared to the control group (57.94 ng/ml) which was statistically significant (p<0.05). 68.4% children had significantly low vitamin D levels and severe form of asthma (p value <0.001). There was also a marked rise in absolute eosinophil count in those who had low vitamin D levels (56.6%) (p-value <0.0001).Conclusions: Vitamin D deficiency is an important risk factor for asthma severity. It modifies the immune system and reduces the inflammation. In the present study, low serum vitamin D levels were significantly correlated with severe form of asthma. There was a significant rise in the absolute eosinophil count in those who exhibited deficiency of vitamin D.

Download Full-text

Prevalence of vitamin D deficiency in children with asthma. Multicenter study

10.1183/13993003.congress-2020.672 ◽

2020 ◽

Author(s):

Elena Kondratyeva ◽

Yuri Mizernitsky ◽

Natalya Ilyenkova ◽

Anna Bogorad ◽

Elena Zhekaite ◽

...

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Multicenter Study ◽

Children With Asthma

Download Full-text

P9‐39: Efficacy of vitamin d supplementation in children with asthma and vitamin D deficiency: A systematic review

Respirology ◽

10.1111/resp.14150_740 ◽

2021 ◽

Vol 26 (S3) ◽

pp. 378-378

Keyword(s):

Systematic Review ◽

Vitamin D ◽

Vitamin D Deficiency ◽

Vitamin D Supplementation ◽

Children With Asthma

Download Full-text

Vitamin D deficiency and changes in serum vitamin D levels with treatment among tuberculosis patients in South Korea

Respirology ◽

10.1111/j.1440-1843.2012.02172.x ◽

2012 ◽

Vol 17 (5) ◽

pp. 808-813 ◽

Cited By ~ 15

Author(s):

HYEON-KYOUNG KOO ◽

JI SUN LEE ◽

YUN JEONG JEONG ◽

SUN MI CHOI ◽

HYO JAE KANG ◽

...

Keyword(s):

Vitamin D ◽

South Korea ◽

Vitamin D Deficiency ◽

Serum Vitamin ◽

Tuberculosis Patients ◽

Serum Vitamin D ◽

Vitamin D Levels

Download Full-text

Vitamin D deficiency in children with asthma

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20204048 ◽

2020 ◽

Vol 7 (10) ◽

pp. 2030

Author(s):

Kasim Resivi Ullerithody ◽

Rajalakshmi Harihara Iyer ◽

Kinattinkara Ramachandran Subharaman

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Chronic Respiratory Diseases ◽

Immune Mediated ◽

Vitamin D Levels ◽

Children With Asthma ◽

Study Population ◽

Routine Physical Examination ◽

The Difference ◽

The Relationship

Background: Asthma is one of the most common chronic respiratory diseases worldwide. Its exact cause remains unknown. Vitamin D has been implicated as a critical regulator of immunity and found to be associated with several immune mediated diseases. Recently there has been increasing interest in the possible link between vitamin D and asthma. Hence, we planned this study to assess the existence of any correlation between asthma and vitamin D levels in India.Methods: Fifty consecutive cases of clinically diagnosed asthma attending asthma clinic and those admitted in IMCH Calicut, Kerala, India were included in the study and administered detailed questionnaire. Routine physical examination and investigation as per the protocol in asthma clinic were done. Blood was drawn for 25 hydroxy cholecalciferol and serum analyzed by Roche Elecsys chemiluminescence assay. Controls were selected only after all fifty cases were selected. Vitamin D levels were assayed in the same manner as in patients with asthma. Vitamin D levels were then analyzed with other parameters and variables. Statistical analysis was performed using SPSS software, version 16.Results: Prevalence of vitamin D deficiency is high in study population. The difference in vitamin D levels between cases and controls is significant.Conclusions: More studies need to be done to ascertain the relationship between asthma and vitamin D in developing countries like India.

Download Full-text