A Clinical Evaluation of Substrate-labeled Fluorescent Immunoassay with Monoclonal Antibody for Determination of Plasma Theophylline Concentration

1984 ◽  
Vol 10 (6) ◽  
pp. 408-412
Author(s):  
YOSHIRO YOKOCHI ◽  
TOSHIAKI NAKAMURA ◽  
IKUO JOHNO ◽  
SHIKIFUMI KITAZAWA
Keyword(s):  
Monoclonal Antibody ◽  
Clinical Evaluation ◽  
Theophylline Concentration ◽  
Plasma Theophylline

Indirect Plasma-Theophylline Monitoring in Asthmatic Children by Determination of Theophylline Concentration in Saliva

PEDIATRICS ◽  
1974 ◽  
Vol 53 (6) ◽  
pp. 873-876
Author(s):  
Gerhard Levy ◽  
Elliot F. Ellis ◽  
Renu Koysooko
Keyword(s):  
Flow Rate ◽  
Maintenance Dose ◽  
Theophylline Concentration ◽  
Asthmatic Children ◽  
Plasma Theophylline ◽  
Mixed Saliva

The concentration of theophylline in mixed saliva and in plasma of 16 asthmatic children on regular theophylline therapy was obtained two and four hours after a maintenance dose. There is a strong and highly statistically significant correlation between the theophylline concentration in saliva and plasma. This correlation is not affected by the pH or flow rate of saliva. The concentration of theophylline in plasma could be predicted from the concentration in saliva within ± 10% in 20, and within ± 20% in all of the 32 samples. Determination of theophylline concentrations in saliva is an effective, convenient, noninvasive, and painless method for routine indirect monitoring of plasma-theophylline concentrations in asthmatic children on regular theophylline therapy.

scholarly journals Determination of Plasma Theophylline Concentration by Immuno-precipitation Inhibition Technique (i-PiT System)

1983 ◽  
Vol 9 (4) ◽  
pp. 295-300
Author(s):  
SHIGERU MOTOYAMA ◽  
JOJI KOBAYASHI ◽  
MICHIHARU HAYATA ◽  
SHOICHIRO YOSHIMURA ◽  
MICHIAKI HORIBA ◽  
...  
Keyword(s):  
Theophylline Concentration ◽  
Precipitation Inhibition ◽  
Plasma Theophylline ◽  
Inhibition Technique

scholarly journals Determination of 1,5‒anhydro‒glucitol–carrier protein conjugates by matrix‒assisted laser desorption/ionization tof mass spectrometry and antibody formation

2000 ◽  
Vol 14 (3) ◽  
pp. 85-92 ◽  
Author(s):  
Li-Jiang Xuan ◽  
Hiroyuki Tanaka ◽  
Satoshi Morimoto ◽  
Yukihiro Shoyama ◽  
Hiroshi Akanuma ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Serum Albumin ◽  
Laser Desorption ◽  
Laser Desorption Ionization ◽  
Protein Conjugates ◽  
Desorption Ionization ◽  
Chicken Lysozyme ◽  
Matrix Assisted Laser ◽  
Matrix Assisted Laser Desorption

In order to prepare the monoclonal antibody against 1,5-anhydro-glucitol (1), it was conjugated with bovine serum albumin (BSA), human serum albumin (HSA) or chicken lysozyme (CL) using succinate orβ-alanine succinate as a spacer to produce individual antigen conjugates. The number of hapten contained in each antigen conjugate was determined by matrix-assisted laser desorption/ionization tof mass (MALDI-tof-MS) spectrometry. The formation of monoclonal antibody (MAb) was also discussed.

Determination of serum tetranectin: technical and clinical evaluation of three sandwich immunoassays

1998 ◽  
Vol 276 (1) ◽  
pp. 19-34 ◽  
Author(s):  
Annemette V Thougaard ◽  
Claus K. Høgdall ◽  
Susanne K Kjær ◽  
Jan Blaakær ◽  
Irakli Jaliashvili ◽  
...  
Keyword(s):  
Clinical Evaluation

scholarly journals Clinical evaluation of tumor targeting with the anticarcinoembryonic antigen murine monoclonal antibody fragment, MN-14 F(ab)2

Cancer ◽  
1996 ◽  
Vol 78 (1) ◽  
pp. 157-168 ◽  
Author(s):  
Malik Juweid ◽  
Robert M. Sharkey ◽  
Thomas M. Behr ◽  
Lawrence C. Swayne ◽  
Robert Dunn ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Clinical Evaluation ◽  
Tumor Targeting ◽  
Antibody Fragment ◽  
Murine Monoclonal Antibody

scholarly journals Determination of Carbohydrate Structure Recognized by Prostate-specific F77 Monoclonal Antibody through Expression Analysis of Glycosyltransferase Genes

2014 ◽  
Vol 289 (23) ◽  
pp. 16478-16486 ◽  
Author(s):  
Motohiro Nonaka ◽  
Michiko N. Fukuda ◽  
Chao Gao ◽  
Zhen Li ◽  
Hongtao Zhang ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Expression Analysis ◽  
Carbohydrate Structure
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