Community prevalence survey of children's blood lead levels and environmental lead contamination in inner Sydney

AbstractLead is a heavy metal without a biological role. High level of lead exposure is known to be associated with hypertension, but the risk at low levels of exposure is uncertain. In this study, data from US NHANES 1999–2016 were analyzed. Adults with blood lead and blood pressure measurements, or self-reported hypertension diagnosis, were included. If not already diagnosed, hypertension was defined according to the AHA/ACC 2017 hypertension guideline. Results were analyzed using R statistics version 3.5.1 with sample weight adjustment. Logistic regression was used to study the association between blood lead level and hypertension. Odds ratio (OR) and 95% confidence interval (95% CI) were estimated. Altogether, 39,477 participants were included. Every doubling in blood lead level was associated with hypertension (OR [95%CI] 1.45 [1.40–1.50]), which remained significant after adjusting for demographics. Using quartile 1 as reference, higher blood lead levels were associated with increased adjusted odds of hypertension (Quartile 4 vs. Quartile 1: 1.22 [1.09–1.36]; Quartile 3 vs. Quartile 1: 1.15 [1.04–1.28]; Quartile 2 vs. Quartile 1: 1.14 [1.05–1.25]). In conclusion, blood lead level is associated with hypertension in the general population with blood lead levels below 5 µg/dL. Our findings suggest that reducing present levels of environmental lead exposure may bring cardiovascular benefits by reducing blood pressure.

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Question Regarding Need for Treatment

PEDIATRICS ◽

10.1542/peds.56.4.621b ◽

1975 ◽

Vol 56 (4) ◽

pp. 621-622

Author(s):

Arthur W. Kaemmer ◽

Byron R. Johnson

Keyword(s):

Mass Screening ◽

Lead Poisoning ◽

Blood Lead ◽

Blood Lead Levels ◽

Elevated Blood ◽

Screening Programs ◽

Environmental Lead ◽

Need For Treatment ◽

Lead Levels ◽

Elevated Blood Lead Levels

Dr. Greensher and his colleagues are to be congratulated for bringing to the readers' attention a most unusual source of lead poisoning. Inasmuch as many localities are initiating city-wide lead screening programs, it is obvious that pediatricians in this country will be seeing many children with abnormally elevated blood lead levels, and in many cases diligent efforts such as this will have to be undertaken to determine the exact source of the environmental lead. biggest problems with mass screening programs for lead poisoning are well outlined by Moriarty's article.2

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The Public Minimization of the Risks Associated With Environmental Lead Exposure and Elevated Blood Lead Levels in Children, Mount Isa, Queensland, Australia

Archives of Environmental & Occupational Health ◽

10.1080/19338240903338189 ◽

2010 ◽

Vol 65 (1) ◽

pp. 45-48 ◽

Cited By ~ 16

Author(s):

Mark Patrick Taylor ◽

Carolyn Schniering

Keyword(s):

Lead Exposure ◽

Blood Lead ◽

Blood Lead Levels ◽

Elevated Blood ◽

The Public ◽

Environmental Lead ◽

Mount Isa ◽

Lead Levels ◽

Environmental Lead Exposure ◽

Elevated Blood Lead Levels

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ASSOCIATIONS BETWEEN BLOOD LEAD LEVELS OF FRENCH CHILDREN AND ENVIRONMENTAL LEAD CONENTRATIONS: PROPOSITIONS OF RISK BASED ENVIRONMENTAL LEAD CONCENTRATIONS LEVELS FOR POLICY MAKING

ISEE Conference Abstracts ◽

10.1289/isee.2011.00444 ◽

2011 ◽

Vol 2011 (1) ◽

Author(s):

Youssef Oulhote ◽

Alain Le Tertre ◽

Anne Etchevers ◽

Barbara Le Bot ◽

Jean Paul Lucas ◽

...

Keyword(s):

Policy Making ◽

Blood Lead ◽

Blood Lead Levels ◽

Environmental Lead ◽

Lead Levels

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Predicting the Children's Blood Lead Level in a Lead and Zinc Smelting Area Based on IEUBK Model

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.1092-1093.687 ◽

2015 ◽

Vol 1092-1093 ◽

pp. 687-691

Author(s):

Fei Chen ◽

Hong Guang Cheng ◽

Xiang Fen Cui

Keyword(s):

Lead Concentration ◽

Lead Level ◽

Blood Lead ◽

Blood Lead Concentration ◽

Blood Lead Levels ◽

Prediction Ability ◽

Environmental Lead ◽

Lead And Zinc ◽

Zinc Smelting ◽

Lead Levels

According to environmental lead exposure data and dietary survey data of lead and zinc smelting area,blood lead levels of children (2~7years old) in study area were predicted with IEUBK model. The children's blood lead concentration predicted value was compared with the corresponding measured value,by comparing the differences, measured the prediction ability of model. The results showed that predicted value and measured value of 2~7 years old children's blood lead concentration in A village were higher than the other villages, they were 33.5μg/dL,30.8μg/dL, respectively; predicted value and measured value of 2~7 years old children's blood lead concentration in I village were the lowest among all villages,they were14.5μg/dL,13.1μg/dL, respectively.By paired T-test showed that the predicted value were higher than the measured value about 1.4~3.4μg/dL,model calculation results slightly overestimated the children's blood lead level.But in general, the predicted value and measured value had a good consistency,through the model prediction could better reflect the children's blood lead levels in the study area.

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