scholarly journals Population Pharmacokinetic Analysis of Therapeutic Drug Monitoring Data in Optimizing Pharmacotherapy of Antiepileptic Drugs

10.5772/20328 ◽  
2011 ◽  
Author(s):  
Katarina Vucicevic ◽  
Branislava Miljkovic ◽  
Sandra Vezmar ◽  
Zoran Todorovic ◽  
Milica Prostran ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Antiepileptic Drugs ◽  
Drug Monitoring ◽  
Population Pharmacokinetic Analysis ◽  
Monitoring Data ◽  
Pharmacokinetic Analysis ◽  
Therapeutic Drug ◽  
Population Pharmacokinetic

scholarly journals Population Pharmacokinetic Analysis of Theophylline : Relationship between Serum Concentrations and Clinical Effects in Therapeutic Drug Monitoring

1999 ◽  
Vol 119 (11) ◽  
pp. 861-867 ◽  
Author(s):  
Koji TANIKAWA ◽  
Yoshiaki MATSUMOTO ◽  
Takashi MATSUZAKI ◽  
Mitsuo MATSUMOTO ◽  
Masamichi FUKUOKA ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Population Pharmacokinetic Analysis ◽  
Pharmacokinetic Analysis ◽  
Therapeutic Drug ◽  
Population Pharmacokinetic ◽  
Clinical Effects ◽  
Serum Concentrations

Population pharmacokinetic model of Vancomycin based on therapeutic drug monitoring data in critically ill septic patients

2020 ◽  
Vol 55 ◽  
pp. 116-121 ◽  
Author(s):  
Tijana Kovacevic ◽  
Branislava Miljkovic ◽  
Pedja Kovacevic ◽  
Sasa Dragic ◽  
Danica Momcicevic ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Critically Ill ◽  
Drug Monitoring ◽  
Population Pharmacokinetic Model ◽  
Pharmacokinetic Model ◽  
Monitoring Data ◽  
Therapeutic Drug ◽  
Population Pharmacokinetic

Population Pharmacokinetic Model of Carbamazepine Derived from Routine Therapeutic Drug Monitoring Data

2007 ◽  
Vol 29 (6) ◽  
pp. 781-788 ◽  
Author(s):  
Katarina Vučićević ◽  
Branislava Miljković ◽  
Ružica Veličković ◽  
Milena Pokrajac ◽  
Aleš Mrhar ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Population Pharmacokinetic Model ◽  
Pharmacokinetic Model ◽  
Monitoring Data ◽  
Therapeutic Drug ◽  
Population Pharmacokinetic ◽  
Routine Therapeutic Drug Monitoring

scholarly journals Validation of a Population Pharmacokinetic Model of Vortioxetine Using Therapeutic Drug Monitoring Data

2021 ◽  
Author(s):  
Trine Frederiksen ◽  
Robert L. Smith ◽  
Birgit M. Wollmann ◽  
Johan Areberg ◽  
Espen Molden
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Population Pharmacokinetic Model ◽  
Pharmacokinetic Model ◽  
Monitoring Data ◽  
Therapeutic Drug ◽  
Population Pharmacokinetic

Influence of aging on serum phenytoin concentrations: a pharmacokinetic analysis based on therapeutic drug monitoring data

2004 ◽  
Vol 59 (2-3) ◽  
pp. 155-165 ◽  
Author(s):  
Dina Battino ◽  
Danilo Croci ◽  
Daniela Mamoli ◽  
Sara Messina ◽  
Emilio Perucca
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Monitoring Data ◽  
Pharmacokinetic Analysis ◽  
Therapeutic Drug

scholarly journals Phenobarbital Pharmacokinetics in Old Age: A Case-matched Evaluation Based on Therapeutic Drug Monitoring Data

Epilepsia ◽  
2005 ◽  
Vol 46 (3) ◽  
pp. 372-377 ◽  
Author(s):  
Sara Messina ◽  
Dina Battino ◽  
Danilo Croci ◽  
Daniela Mamoli ◽  
Sara Ratti ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Old Age ◽  
Drug Monitoring ◽  
Monitoring Data ◽  
Therapeutic Drug

Therapeutic Drug Monitoring of Antiepileptic Drugs in a Tertiary Care Hospital in India

2015 ◽  
Vol 38 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Natarajan Harivenkatesh ◽  
Natarajan Haribalaji ◽  
Darling Chellathai David ◽  
C. M. Prabu Kumar
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Antiepileptic Drugs ◽  
Drug Monitoring ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Therapeutic Drug ◽  
Care Hospital

scholarly journals Therapeutic Drug Monitoring of Second- and Third-Generation Antiepileptic Drugs: Insights From a College of American Pathologists Proficiency Testing Survey

2021 ◽  
Author(s):  
Matthew D. Krasowski ◽  
Thomas A. Long ◽  
Christine L. H. Snozek ◽  
Annabel Dizon ◽  
Barbarajean Magnani ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Antiepileptic Drugs ◽  
Proficiency Testing ◽  
Drug Monitoring ◽  
First Generation ◽  
Therapeutic Drug ◽  
Third Generation ◽  
Enzyme Immunoassays ◽  
Steady Growth ◽  
Survey Results

Context.— Therapeutic drug monitoring has traditionally been widely used for first-generation antiepileptic drugs (AEDs) such as carbamazepine and phenytoin. The last 2 decades have seen the introduction of second- and third-generation AEDs (eg, lamotrigine, levetiracetam, and topiramate) into clinical practice. Objective.— To use data from the College of American Pathologists Therapeutic Drug Monitoring, Extended proficiency testing survey to determine the performance of assays used for therapeutic drug monitoring of newer AEDs, including comparison of enzyme immunoassay and chromatographic techniques. Design.— Six years of proficiency testing surveys were reviewed (2013–2018). Results.— Steady growth was seen in participant volumes for newer AEDs. The analytical performance of automated enzyme immunoassays for lamotrigine, levetiracetam, and topiramate was similar to that of chromatographic methods, consistent with published literature using patient samples for comparisons. The majority of participating laboratories now use enzyme immunoassays to measure levetiracetam. Conclusions.— Survey results reflect steadily growing interest in therapeutic drug monitoring of newer AEDs. The increasing availability of robust immunoassays for new AEDs should facilitate their clinical utility, especially for clinical laboratories that do not perform chromatographic assays for therapeutic drug monitoring.

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