scholarly journals Mechanisms of Glucocorticoid Receptor (GR) Mediated Corticotropin Releasing Hormone Gene Expression

10.5772/54844 ◽  
2012 ◽  
Author(s):  
Rosalie M.
Keyword(s):  
Gene Expression ◽  
Glucocorticoid Receptor ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

Gene expression profiling reveals corticotropin-releasing hormone (CRH) dependent signaling pathways

2005 ◽  
Vol 38 (05) ◽  
Author(s):  
JM Deussing ◽  
C Kühne ◽  
M Panhuysen ◽  
B Pütz ◽  
J Breu ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Signaling Pathways ◽  
Expression Profiling ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

scholarly journals Androgens Drive Sex Biases in Hypothalamic Corticotropin-Releasing Hormone Gene Expression After Adrenalectomy of Mice

Endocrinology ◽  
2019 ◽  
Vol 160 (7) ◽  
pp. 1757-1770 ◽  
Author(s):  
Ashley L Heck ◽  
Robert J Handa
Keyword(s):  
Gene Expression ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Sex Biases

Effects of corticotropin-releasing hormone and its antagonist on the gene expression of gonadotrophin-releasing hormone (GnRH) and GnRH receptor in the hypothalamus and anterior pituitary gland of follicular phase ewes

2011 ◽  
Vol 23 (6) ◽  
pp. 780 ◽  
Author(s):  
Magdalena Ciechanowska ◽  
Magdalena Łapot ◽  
Tadeusz Malewski ◽  
Krystyna Mateusiak ◽  
Tomasz Misztal ◽  
...  
Keyword(s):  
Gene Expression ◽  
Pituitary Gland ◽  
Anterior Pituitary ◽  
Follicular Phase ◽  
Gnrh Receptor ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Gonadotrophin Releasing Hormone ◽  
Lh Secretion ◽  
Crh Receptors

There is no information in the literature regarding the effect of corticotropin-releasing hormone (CRH) on genes encoding gonadotrophin-releasing hormone (GnRH) and the GnRH receptor (GnRHR) in the hypothalamus or on GnRHR gene expression in the pituitary gland in vivo. Thus, the aim of the present study was to investigate, in follicular phase ewes, the effects of prolonged, intermittent infusion of small doses of CRH or its antagonist (α-helical CRH 9-41; CRH-A) into the third cerebral ventricle on GnRH mRNA and GnRHR mRNA levels in the hypothalamo–pituitary unit and on LH secretion. Stimulation or inhibition of CRH receptors significantly decreased or increased GnRH gene expression in the hypothalamus, respectively, and led to different responses in GnRHR gene expression in discrete hypothalamic areas. For example, CRH increased GnRHR gene expression in the preoptic area, but decreased it in the hypothalamus/stalk median eminence and in the anterior pituitary gland. In addition, CRH decreased LH secretion. Blockade of CRH receptors had the opposite effect on GnRHR gene expression. The results suggest that activation of CRH receptors in the hypothalamus of follicular phase ewes can modulate the biosynthesis and release of GnRH through complex changes in the expression of GnRH and GnRHR genes in the hypothalamo–anterior pituitary unit.

scholarly journals Regulatory Mechanisms of Corticotropin-Releasing Hormone and Vasopressin Gene Expression in the Hypothalamus

2004 ◽  
Vol 16 (4) ◽  
pp. 348-355 ◽  
Author(s):  
K. Itoi ◽  
Y.-Q. Jiang ◽  
Y. Iwasaki ◽  
S. J . Watson
Keyword(s):  
Gene Expression ◽  
Regulatory Mechanisms ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Vasopressin Gene

scholarly journals Regulation of Human Corticotropin- Releasing Hormone Gene Expression by 3′,5′-Cyclic Adenosine Monophosphate in a Transformed Mouse Corticotroph Cell Line

1989 ◽  
Vol 3 (10) ◽  
pp. 1537-1544 ◽  
Author(s):  
Richard I. Dorin ◽  
Hideo Takahashi ◽  
Yoshikatsu Nakai ◽  
Junichi Fukata ◽  
Yoshiyuki Naitoh ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Line ◽  
Cyclic Adenosine Monophosphate ◽  
Adenosine Monophosphate ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone
Sign in / Sign up

Export Citation Format

Share Document