scholarly journals Ischemic Ulcer Healing: Does Appropriate Flow Reconstruction Stand for All That We Need?

10.5772/64834 ◽  
2016 ◽  
Author(s):  
Vlad-Adrian Alexandrescu ◽  
François Triffaux
Keyword(s):  
Ulcer Healing ◽  
Ischemic Ulcer ◽  
Flow Reconstruction

scholarly journals Limb Revascularization in Patients with Diabetes Mellitus

2019 ◽  
Vol 23 (4) ◽  
pp. 349-363
Author(s):  
L. A. Bokeria ◽  
V. S. Arakelyan ◽  
V. G. Papitashvili ◽  
Sh. Sh. Tsurtsumiya
Keyword(s):  
Diabetes Mellitus ◽  
Surgical Treatment ◽  
Ulcer Healing ◽  
Diabetic Patients ◽  
Complication Rates ◽  
Peripheral Arteries ◽  
Ischemic Ulcer ◽  
Patients With Diabetes ◽  
Basic Treatment

The review describes morbidity, mortality and possible complication rates for diabetic patients with peripheral arteries disease. The article demonstrates the modern tendency in the surgical treatment of peripheral arteries atherosclerosis, shows and compares worldwide results of endovascular and open revascularization. The authors have assessed the risk of amputation for patients with diffuse peripheral arteries disease and described basic treatment principals for better chronic ischemic ulcer healing.

scholarly journals Results of Infrapopliteal Endovascular Procedures Performed in Diabetic Patients with Critical Limb Ischemia and Tissue Loss from the Perspective of an Angiosome-Oriented Revascularization Strategy

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Francisco Acín ◽  
César Varela ◽  
Ignacio López de Maturana ◽  
Joaquín de Haro ◽  
Silvia Bleda ◽  
...  
Keyword(s):  
Limb Salvage ◽  
Ulcer Healing ◽  
Endovascular Procedures ◽  
Limb Ischemia ◽  
Tissue Loss ◽  
Diabetic Patients ◽  
Critical Ischemia ◽  
Ischemic Ulcer ◽  
Anatomical Classification ◽  
Ischemic Ulcers

Our aim was to describe our experience with infrapopliteal endovascular procedures performed in diabetic patients with ischemic ulcers and critical ischemia (CLI). A retrospective study of 101 procedures was performed. Our cohort was divided into groups according to the number of tibial vessels attempted and the number of patent tibial vessels achieved to the foot. An angiosome anatomical classification of ulcers were used to describe the local perfusion obtained after revascularization. Ischemic ulcer healing and limb salvage rates were measured. Ischemic ulcer healing at 12 months and limb salvage at 24 months was similar between a single revascularization and multiple revascularization attempts. The group in whom none patent tibial vessel to the foot was obtained presented lower healing and limb salvage rates. No differences were observed between obtaining a single patent tibial vessel versus more than one tibial vessel. Indirect revascularization of the ulcer through arterial-arterial connections provided similar results than those obtained after direct revascularization via its specific angiosome tibial artery. Our results suggest that, in CLI diabetic patients with ischemic ulcers that undergo infrapopliteal endovascular procedures, better results are expected if at least one patent vessel is obtained and flow is restored to the local ischemic area of the foot.

Abstract 6054: Immersing Feet in CO 2 -Rich Water-Bath Improves Ulcer Healing on Ischemic Limb after Infrainguinal Bypass Surgery

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Hisae Hayashi ◽  
Yoshitaka Kumada ◽  
Kyuichi Furuhashi ◽  
Hiroshi Takahashi ◽  
Takanobu Toriyama ◽  
...  
Keyword(s):  
Ulcer Healing ◽  
Standard Care ◽  
Bypass Surgery ◽  
Controlled Trial ◽  
Complete Healing ◽  
Control Group ◽  
Transcutaneous Oxygen ◽  
Ischemic Limb ◽  
Ischemic Ulcer ◽  
Infrainguinal Bypass

Background : We have shown that immersion of feet in warmed water enriched with carbon dioxide (CO 2 immersion) improves subcutaneous microcirculation in critical limb ischemia (CLI) with ischemic ulcer/gangrene. Using an animal model, other group has reported that the CO 2 immersion enhances collateral blood flow in ischemic limb via mobilization of endothelial progenitor cells and activation of NO-cGMP system. For CLI patients with ulcer/gangrene, infrainguinal bypass surgery is the standard therapy. However, ulcer healing and prevention of amputation still remain suboptimal. In order to know whether the CO 2 immersion improves the clinical efficacy, here we performed the CO 2 immersion after infrainguinal bypass surgery. Methods : This study was designed as a prospective controlled trial. Fifty-five patients with ischemic ulcer/gangrene underwent the standard care including successful infrainguinal bypass surgery were enrolled and were randomly divided into the two groups; patients underwent standard care added CO 2 immersion (CO 2 group, 27 patients with 30 limbs) and patients received standard care alone (control group, 28 patients with 30 limbs). The patients in the CO 2 group immersed their feet in CO 2 enriched water (depth of 20 –30 cm, 37–38°C, duration for 10 minutes) twice a day. Primary endpoint was defined as complete healing of ischemic ulcers. Results : Baseline demographical data, traditional risk factors, surgical procedure, ankle pressure and transcutaneous oxygen pressure (tcPO 2 ) were comparable between the two groups. Rate of the complete ulcer healing after 1-year was much higher in the CO 2 group than in the control group (43.3% vs. 20.0%, HR 2.72, 95%CI 1.03–7.17, p=0.043). Cox multivariate analysis revealed that CO 2 immersion (HR 4.13, 95%CI 1.09 –15.75, p=0.038), diabetes (HR 0.020, 95%CI 0.01–.303, p=0.005) and tcPO 2 (HR 1.04, 95%CI 1.00 –1.09, p=0.050) were independent predictors for complete ulcer healing. In contrast, rates of 1-year mortality, graft patency and limbs salvage showed no significant differences between 2 groups (p=0.55, p=0.47 and p=0.16, respectively). Conclusion : The CO 2 immersion after infrainguinal bypass surgery provided additional benefit for the ulcer healing in CLI patients with ulcer/gangrene.

Gastric ulcer healing is regulated by platelets through endostatin release: Modulation by ticlopidine, aspirin and celecoxib

2001 ◽  
Vol 120 (5) ◽  
pp. A143-A143
Author(s):  
L MA ◽  
S ELLIOTT ◽  
G CIRINO ◽  
A BURET ◽  
J WALLACE
Keyword(s):  
Gastric Ulcer ◽  
Ulcer Healing ◽  
Gastric Ulcer Healing

Spray-On Cells Found to Promote Venous Ulcer Healing

2012 ◽  
Vol 43 (9) ◽  
pp. 6
Author(s):  
SHARON WORCESTER
Keyword(s):  
Ulcer Healing ◽  
Venous Ulcer

Aspirin Did Not Slow Ulcer Healing in PPI Users

2011 ◽  
Vol 41 (11) ◽  
pp. 9
Author(s):  
PATRICE WENDLING
Keyword(s):  
Ulcer Healing

Factors influencing gastric ulcer healing in H. pylori positive patients

2008 ◽  
Vol 46 (05) ◽  
Author(s):  
P Nagy ◽  
M Gottlow ◽  
Z Tulassay
Keyword(s):  
Gastric Ulcer ◽  
Ulcer Healing ◽  
Gastric Ulcer Healing ◽  
Factors Influencing ◽  
H Pylori

Retrospective review on the effectiveness of compression therapy in venous leg ulcer healing at a wound care centre in Hong Kong

WCET Journal ◽  
2019 ◽  
Vol 39 (4) ◽  
pp. 24
Author(s):  
Michelle Lee ◽  
Ka Wai Wong ◽  
Ka Kay Chan
Keyword(s):  
Hong Kong ◽  
Ulcer Healing ◽  
Retrospective Review ◽  
Wound Care ◽  
Compression Therapy ◽  
Leg Ulcer ◽  
Care Centre ◽  
Venous Leg Ulcer

Description of venous leg ulcer healing mechanism

Leczenie Ran ◽  
2015 ◽  
Vol 12 (2) ◽  
pp. 49-58
Author(s):  
Wojciech Twardokęs ◽  
Agata Kołodziej ◽  
Andrzej Ślęzak
Keyword(s):  
Ulcer Healing ◽  
Leg Ulcer ◽  
Venous Leg Ulcer

High voltage pulsed current in pressure ulcer healing: results of a randomized, controlled trial – preliminary study

Leczenie Ran ◽  
2013 ◽  
Vol 10 (1) ◽  
pp. 13-22 ◽  
Author(s):  
Anna Polak ◽  
Anna Walczak ◽  
Jakub Taradaj ◽  
Marzena Dzikiewicz ◽  
Aldona Augustak ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Pressure Ulcer ◽  
High Voltage ◽  
Ulcer Healing ◽  
Controlled Trial ◽  
Pulsed Current ◽  
Randomized Controlled ◽  
Preliminary Study
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