scholarly journals Errors in Surgical Pathology Laboratory

Author(s):  
Monique Freire Santana ◽  
Luiz Carlos de Lima Ferreira

1983 ◽  
Vol 130 (5) ◽  
pp. 1029-1029
Author(s):  
S.H. Rosenheim ◽  
J.H. Volz


2011 ◽  
Vol 9 (3) ◽  
pp. 245-251 ◽  
Author(s):  
Sandra A. McDonald ◽  
Rebecca D. Chernock ◽  
Tracey A. Leach ◽  
Ajaz A. Kahn ◽  
James H. Yip ◽  
...  


Author(s):  
Ashwini Tangde ◽  
Vaidik Shrivastava ◽  
Anil Joshi

Background: Frozen section (FS) is a rapid diagnostic procedure performed on tissues obtained intraoperatively. This method serves useful purposes, such as determining the malignancy or benignancy of a suspected lesion, determining the adequacy of a biopsy of a suspected lesion, confirming the presence or absence of metastasis, and identifying small structures. But it bears many disadvantages and limitations, the most of which is the danger of incorrect diagnosis. Therefore, it is critical to determine efficiency of frozen section performance periodically.  This study was performed to determine accuracy of frozen section by correlating the intra-operative frozen section diagnosis with final diagnosis on permanent sections.Methods: In this retrospective study, authors compared the results of frozen section with their final permanent section diagnosis in Government Medical College and Hospital, Aurangabad, Maharashtra, India during January 2017 to December 2018.Results: Study comprises 83 patients, of which 73 were female and 10 were male. Out of 83 cases, the diagnosis of 76 cases was concordant with conventional histopathology diagnosis while seven were discordant. This gave overall accuracy rate of 91.57% and discordant rate of 8.43%. The overall sensitivity was 85.71% and specificity was 97.92%. The positive predictive and negative predictive value was 96.77% and 90.38% respectively.Conclusions: The accuracy, sensitivity, specificity of frozen section diagnosis in this study  are comparable with most international quality control statistics for frozen sections. The results suggest that the correlation of intra-operative frozen section diagnosis with the final histopathological diagnosis on permanent sections forms an integral part of quality assurance activities in the surgical pathology laboratory and specific measures should be taken to reduce the number of discrepancies.



2004 ◽  
Vol 27 (2) ◽  
pp. 113-117 ◽  
Author(s):  
Yen Tan ◽  
Maryam H. Hilmy ◽  
Huynh Hung ◽  
Puay-Hoon Tan


2011 ◽  
Vol 135 (2) ◽  
pp. 215-219
Author(s):  
Fabio Pagni ◽  
Francesca Bono ◽  
Camillo Di Bella ◽  
Agostino Faravelli ◽  
Anna Cappellini

Abstract Only 1 surgical pathology laboratory is available in Zambia, a country with a population of 12 million people. Since 2004 the Italian association of pathologists Patologi Oltre Frontiera has been working to create a virtual laboratory through the use of telemedicine. The project has involved staining histologic preparations on site, with the interpretation of imaged slides performed abroad through telepathology. Starting in April 2007, all surgical specimens obtained in Mtendere Mission Hospital, Chirundu, Zambia, were submitted for microscopic examination through whole-slide scans. Two independent Italian pathologists evaluated the cases by means of satellite connection and the final diagnoses were sent to Zambian clinicians via the internet. This article describes the spectrum of diagnoses made via telepathology for the Zambian population. Also, we analyze the concordant and discordant data between this telepathology method and traditional microscopy in a developing country. Moreover, we provide possible solutions for providing pathology services in other underdeveloped countries.



1982 ◽  
Vol 13 (5) ◽  
pp. 272-278 ◽  
Author(s):  
Rodger C. Haggitt


Author(s):  
John C. Lee

Electron microscopic examination of surgical biopsy material is occasionally used in teaching hospitals as an aid to tissue diagnosis. Although the value of ultrastructural studies in a surgical pathology laboratory is undisputed in some instances, electron microscopy often merely serves to satisfy scientific curiosity and has little advantage over good light microscopy.In 1967 an electron microscope service unit was installed as part of the surgical pathology laboratory of the University of California, San Francisco, and has been utilized for ultrastructural studies on a fee-for-service basis. Some of the income of this laboratory is derived from fees paid from research grants for the examination of various experimental animal tissues. A large proportion, however, stems from fees for examining human biopsy material. Hospital insurance carriers are willing to pay reasonable amounts for this service when it benefits the patient.



2008 ◽  
Vol 132 (2) ◽  
pp. 181-185 ◽  
Author(s):  
Raouf E. Nakhleh

Abstract Context.—National patient safety goals and error reduction efforts should be addressed by each surgical pathology laboratory. Objective.—To review issues relevant to patient safety and error reduction in surgical pathology in the context of continuous quality improvement. Data Sources.—The literature is reviewed. Conclusions.—Patient safety goals can and should be addressed within the context of a quality improvement plan. Multiple factors that contribute to errors in surgical pathology are discussed. The current literature defines the extent of these problems within specific segments of the test cycle (preanalytic, analytic, and postanalytic). Potential solutions are presented that may reduce or avoid errors. In addition, general principles are outlined that enhance the laboratory's ability to successfully and continuously address patient safety and error reduction.



1988 ◽  
pp. 139-151
Author(s):  
P. J. M. Rijntjes ◽  
W. G. V. Quint ◽  
C. J. Herman


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