Epstein-Barr Virus Infection and Risk of Breast Cancer: An Adaptive Meta-Analysis for Case-Control Studies

Author(s):  
Jong-Myon Bae ◽  
Eun Hee Kim
2019 ◽  
Vol 15 (24) ◽  
pp. 2873-2885 ◽  
Author(s):  
Mohammad Farahmand ◽  
Seyed Hamidreza Monavari ◽  
Zabihollah Shoja ◽  
Hadi Ghaffari ◽  
Mehdi Tavakoli ◽  
...  

Despite the numerous publications regarding the role of Epstein–Barr virus (EBV) in breast cancer development, the topic has still remained controversial. The aim of the meta-analysis was to estimate the overall prevalence of EBV in the breast cancer population, and to investigate the association between EBV and breast cancer risk. The overall prevalence of EBV was calculated 26.37% (95% CI: 22–31%) from the 44 included studies. Meta-analysis of 30 case–control studies showed that the pooled association between EBV and risk of breast cancer is odds ratio 4.74 (95% CI: 2.92–7.69; Z = 6.30; p < 0.0001). Our analyses indicate a strong statistical relationship between EBV infection and risk of breast cancer, suggesting a potential role of EBV infection in the development of breast cancer.


BMC Cancer ◽  
2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Xuechao Liu ◽  
Jianjun Liu ◽  
Haibo Qiu ◽  
Pengfei Kong ◽  
Shangxiang Chen ◽  
...  

2011 ◽  
Vol 47 (1) ◽  
pp. 116-120 ◽  
Author(s):  
Calypse B. Agborsangaya ◽  
Tuula Lehtinen ◽  
Adetunji T. Toriola ◽  
Eero Pukkala ◽  
Helja-Marja Surcel ◽  
...  

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