scholarly journals Comparative Study Between Serum Level of Total L-carnitine in Neonatal Hypoxic Ischemic Encephalopathy (HIE) and Transient Tachypnea of the Newborn (TTN)

2021 ◽  
Vol 12 (3) ◽  
Author(s):  
Amira M. Shalaby ◽  
Eman Fathala Gad ◽  
Eman Mohammed Salah Eldin ◽  
Safiea A. El-Deeb ◽  
Safwat M. Abdel-Aziz
Keyword(s):  
Serum Level ◽  
Serum Creatinine ◽  
Serum Creatinine Level ◽  
Creatinine Level ◽  
Serum Sodium ◽  
Sodium Level ◽  
Serum Sodium Level ◽  
Hypoxic Ischemic Encephalopathy ◽  
Male Factor ◽  
Ischemic Encephalopathy

Background: Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the most common causes of cerebral palsy. Objectives: We aimed to compare the serum levels of total L-carnitine in newborns with HIE and transient tachypnea of newborn and to determine the correlation between associated demographic data, associated changes in laboratory findings, and outcome in cases with HIE. Methods: This comparative, prospective, and observational study was conducted at the Neonatal Intensive Care Unit (NICU) of University Children Hospital. All the cases of perinatal asphyxia and TTN admitted to the NICU during 2016 - 2018 were included. Results: It was found that the serum level of total L-carnitine decreased in both HIE (I) and TTN (II) cases, but the difference was not significant (5.51 ± 1.30 µmol/L in group I vs. 6.22 ± 2.56 µmol/l in group II). Male factor with changes in the serum sodium level (132.63 ± 9.30) and abnormal serum creatinine level (1.4 [0.7 - 15.0]) were significantly related to the outcome of HIE cases. Conclusions: The serum level of total L-carnitine declined in both HIE and TTN cases. Male factor with changes in serum sodium level and abnormal serum creatinine level were significantly related to the mortality of cases with HIE.

scholarly journals Prediction of contrast-induced nephropathy by the serum creatinine level on the day following cardiac catheterization

2016 ◽  
Vol 68 (5) ◽  
pp. 412-418 ◽  
Author(s):  
Makoto Watanabe ◽  
Yoshihiko Saito ◽  
Kazutaka Aonuma ◽  
Atsushi Hirayama ◽  
Nagara Tamaki ◽  
...  
Keyword(s):  
Serum Creatinine ◽  
Serum Creatinine Level ◽  
Creatinine Level ◽  
Cardiac Catheterization ◽  
Contrast Induced Nephropathy

scholarly journals Gambaran Kadar Kreatinin Serum dan Estimasi Laju Filtrasi Glomerulus (eLFG) pada Wanita Hamil Normal

2017 ◽  
Vol 5 (2) ◽  
Author(s):  
. Sumardiani ◽  
Glady I. Rambert ◽  
Arthur E. Mongan
Keyword(s):  
Serum Creatinine ◽  
Serum Creatinine Level ◽  
Pregnant Women ◽  
Creatinine Level ◽  
Creatine Phosphate ◽  
Cross Sectional ◽  
Probability Sampling ◽  
Purposive Sampling ◽  
Laboratory Examinations ◽  
Cross Sectional Design

Abstract: Creatinine is the end result of the metabolism of muscle creatine phosphate which was synthesized in the kidney. Serum creatinine level can normally decrease during pregnancy due to hyperfiltation of the renal glomeruli. Estimation of glomerular filtration rate (GFR) with CKD-EPI formula is beneficially used in populations with GFR >60 ml/min/1.73m2 especially in pregnant women. The creatinine levels of normal pregnant women are lower than of non-pregnant women and pregnant women with pre-eclampsia. This study was aimed to obtain the serum creatinine level and estimated GFR (eGFR) in normal pregnant women. This was a descriptive observational study with a cross sectional design. Samples were obtained by using non-probability sampling of purposive sampling method. Blood samples of 30 normal pregnant women were obtained at three Public Health Centers (Minanga, Sario, and Bahu Manado) from October to November 2017. The laboratory examinations revealed that all samples (100%) showed decreased serum creatinine levels with a mean of 0.53 mg/dL and increased eGRF >90 ml/min/1.73m2. Conclusion: During pregnancy, there was an increase in eGFR and a decrease in serum creatinine level in all trimesters.Keywords: normal pregnant women, serum creatinine, eGFR Abstrak: Kreatinin merupakan hasil akhir metabolisme dari kreatin fosfat otot, yang awalnya disintesis di ginjal. Pemeriksaan kreatinin sering digunakan untuk mengetahui fungsi ginjal. Kadar kreatinin serum normalnya dapat menurun selama kehamilan karena terjadi hiperfiltasi glomerulus ginjal. Estimasi Laju Filtrasi Glomerulus (eLFG) dengan formula CKD-EPI lebih baik digunakan pada populasi dengan laju filtrasi glomerulus >60 ml/min/1,73m2 khususnya wanita hamil. Kadar kreatinin wanita hamil normal lebih rendah daripada wanita tidak hamil dan wanita hamil dengan pre-eklampsi. Penelitian ini bertujuan untuk mengetahui gamabaran kreatinin serum dan eLFG pada wanita hamil normal. Jenis penelitian ialah deskriptif observasional dengan desain potong lintang. Sampel diambil dengan cara non-probability sampling jenis purposive sampling. Sampel penelitian ialah sampel darah dari 30 wanita hamil normal yang memeriksakan diri di Puskesmas Minanga, Sario, dan Bahu selama bulan Oktober-November 2017. Berdasarkan hasil pemeriksaan laboratorium didapatkan 30 orang (100%) wanita hamil normal mengalami penurunan kreatinin dengan rerata 0,53 mg/dL dan peningkatan laju filtrasi glomerulus dengan nilai eLFG >90 ml/min/1,73m2. Simpulan: Selama kehamilan terjadi peningkatan eLFG dan penurunan kreatinin serum pada semua trimester.Kata kunci: wanita hamil normal, kreatinin serum, eLFG

scholarly journals Classifying AKI by Urine Output versus Serum Creatinine Level

2015 ◽  
Vol 26 (9) ◽  
pp. 2231-2238 ◽  
Author(s):  
John A. Kellum ◽  
Florentina E. Sileanu ◽  
Raghavan Murugan ◽  
Nicole Lucko ◽  
Andrew D. Shaw ◽  
...  
Keyword(s):  
Serum Creatinine ◽  
Serum Creatinine Level ◽  
Creatinine Level ◽  
Urine Output
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