Quadriplegia as a Rare Complication of Black Widow Spider Envenomation

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Bita Dadpour ◽  
Alireza Ghodsi ◽  
Helia Farham

Introduction: The bite of Latrodectus tredecimguttatus, generally known as the Black Widow Spider (BWS), can cause a variety of symptoms, including muscular spasm, back pain, abdominal pain, severe sweating, and shivering. The bite brings weakness, too; however, quadriplegia has not been mentioned in the literature. Case Presentation: Here, we present a 42-year-old male with BWS bite who developed muscle weakness and paralysis in the four limbs. The patient needed mechanical ventilation. Nerve conduction velocity showed myopathy in the patient. The patient could eventually walk after 45 days of supportive treatment. Conclusions: It can be hypothesized that quadriplegia may happen due to the vast acetylcholine depletion.

2017 ◽  
Vol 2 (1) ◽  
pp. 12-16 ◽  
Author(s):  
Irena Çeko Marko ◽  
◽  
Enkeleida Gjiçali ◽  
Sonil Marko ◽  
Ilir Alimehmeti ◽  
...  

2021 ◽  
Vol 250 (3333) ◽  
pp. 11
Author(s):  
Christa Lesté-Lasserre

1976 ◽  
Vol 194 (1115) ◽  
pp. 195-210 ◽  

Some properties of spontaneous miniature potentials at denervated frog motor endplates (Schwann cell-min. e. p. ps) have been investigated. Schwann cell-min. e. p. ps showed a slower and more variable time course than min. e. p. ps at inneryated endplates. The occurrence of Schwann cell-min. e. p. ps usually obeyed Poisson statistics and in the absence of experimental treatment their mean frequency remained stable for several hours. Schwann cell-min. e. p. p. frequency increased with increasing temperature. A logarithmic relation was observed with a mean Q 10 of 4.87 ± 0.37. In other experiments a Q 10 of 9.50 ± 0.63 was found for min. e. p. ps at innervated endplates. Lanthanum and manganese ions, black widow spider venom, ethanol, diamide, ouabain, theophylline and acid Ringer’s solution, all of which increased normal min. e. p. p. frequency, failed to raise the frequency of Schwann cell-min. e. p. ps. Lanthanum, ethanol, ouabain and low pH depressed the frequency, while black widow spider venom, diamide, theophyline and manganese were without significant effect. Adenosine, which depresses min. e. p. p. frequency at innervated endplates, had no effect on spontaneous miniature potentials at denervated endplates. Removal of Ca 2+ from the external medium reduced the frequency of Schwann min. e. p. ps; and a decrease was also seen in one experiment where the Ca 2+ concentration was raised from 1.8 to 10 mM. Diluting the Ringer’s solution raised Schwann cell-min. e. p. p. frequency transiently. This increase resulted from a reduction in osmolarity, not in the ionic strength, of the medium.


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