scholarly journals Advanced Virtual Monochromatic Images from Dual Source Dual-Energy CT for a Reduction in the Contrast Medium Dose (389 mgI/kg) in Multiphase Liver CT: Evaluation of Image Quality and Focal Lesion Conspicuity

2019 ◽  
Vol 16 (3) ◽  
Author(s):  
Ji Eun Kim ◽  
Hyun Ok Kim ◽  
Kyungsoo Bae ◽  
Jae Min Cho ◽  
Ho Cheol Choi ◽  
...  
Author(s):  
S. Sawall ◽  
L. Klein ◽  
E. Wehrse ◽  
L. T. Rotkopf ◽  
C. Amato ◽  
...  

Abstract Objective To evaluate the dual-energy (DE) performance and spectral separation with respect to iodine imaging in a photon-counting CT (PCCT) and compare it to dual-source CT (DSCT) DE imaging. Methods A semi-anthropomorphic phantom extendable with fat rings equipped with iodine vials is measured in an experimental PCCT. The system comprises a PC detector with two energy bins (20 keV, T) and (T, eU) with threshold T and tube voltage U. Measurements using the PCCT are performed at all available tube voltages (80 to 140 kV) and threshold settings (50–90 keV). Further measurements are performed using a conventional energy-integrating DSCT. Spectral separation is quantified as the relative contrast media ratio R between the energy bins and low/high images. Image noise and dose-normalized contrast-to-noise ratio (CNRD) are evaluated in resulting iodine images. All results are validated in a post-mortem angiography study. Results R of the PC detector varies between 1.2 and 2.6 and increases with higher thresholds and higher tube voltage. Reference R of the EI DSCT is found as 2.20 on average overall phantoms. Maximum CNRD in iodine images is found for T = 60/65/70/70 keV for 80/100/120/140 kV. The highest CNRD of the PCCT is obtained using 140 kV and is decreasing with decreasing tube voltage. All results could be confirmed in the post-mortem angiography study. Conclusion Intrinsically acquired DE data are able to provide iodine images similar to conventional DSCT. However, PCCT thresholds should be chosen with respect to tube voltage to maximize image quality in retrospectively derived image sets. Key Points • Photon-counting CT allows for the computation of iodine images with similar quality compared to conventional dual-source dual-energy CT. • Thresholds should be chosen as a function of the tube voltage to maximize iodine contrast-to-noise ratio in derived image sets. • Image quality of retrospectively computed image sets can be maximized using optimized threshold settings.


2019 ◽  
Vol 124 (8) ◽  
pp. 745-752 ◽  
Author(s):  
Andrea Agostini ◽  
Alberto Mari ◽  
Cecilia Lanza ◽  
Nicolo’ Schicchi ◽  
Alessandra Borgheresi ◽  
...  

2014 ◽  
Vol 203 (4) ◽  
pp. 838-845 ◽  
Author(s):  
Achille Mileto ◽  
Juan Carlos Ramirez-Giraldo ◽  
Daniele Marin ◽  
Marcela Alfaro-Cordoba ◽  
Christian D. Eusemann ◽  
...  

2011 ◽  
Vol 38 (12) ◽  
pp. 6371-6379 ◽  
Author(s):  
Lifeng Yu ◽  
Jodie A. Christner ◽  
Shuai Leng ◽  
Jia Wang ◽  
Joel G. Fletcher ◽  
...  

2019 ◽  
Vol 29 (9) ◽  
pp. 4603-4612 ◽  
Author(s):  
Lukas Lenga ◽  
Franziska Trapp ◽  
Moritz H. Albrecht ◽  
Julian L. Wichmann ◽  
Addison A. Johnson ◽  
...  

2010 ◽  
Vol 195 (5) ◽  
pp. 1164-1174 ◽  
Author(s):  
Andrew N. Primak ◽  
Juan Carlos Ramirez Giraldo ◽  
Christian D. Eusemann ◽  
Bernhard Schmidt ◽  
Birgit Kantor ◽  
...  

2011 ◽  
Vol 22 (2) ◽  
pp. 279-286 ◽  
Author(s):  
Tobias De Zordo ◽  
Klemens von Lutterotti ◽  
Christian Dejaco ◽  
Peter F. Soegner ◽  
Renate Frank ◽  
...  

Author(s):  
Swathigha Selvaraj ◽  
Niyas N. P. ◽  
Rupa Renganathan ◽  
Rajkumar Ramasamy ◽  
Rinoy Ram Anandan ◽  
...  

Abstract Objectives The aims of our study were to assess the comparability of conventional unenhanced images (CUIs) of hepatopancreaticobiliary system with virtual unenhanced images (VUIs) derived from arterial and portal venous phases acquired in a third-generation, dual-source, dual-energy CT (DECT), and also to assess the best dataset among these VUIs. We also calculated the radiation effective dose (ED) reduction by eliminating noncontrast acquisition. Materials and Methods 60 patients were included in our study. Unenhanced images in single energy and contrast-enhanced images in dual-energy mode were acquired. Arterial virtual unenhanced (AVU) and portal virtual unenhanced (PVU) images were generated and compared with CUI, using both objective and subjective methods. The ED was calculated separately for each phase. Statistical significance between difference in mean attenuation values were analyzed using ANOVA and unpaired student t-test. Results In our study, the difference in mean attenuation of liver, spleen, and pancreas between the three phases—CU, AVU, and PVU—were insignificant with p-value > 0.05. This indicates that the values were comparable. Among the VUI, AVU images were statistically superior in image quality. Elimination of noncontrast CT from triple phase abdominal imaging can achieve an average ED reduction of 39%. Conclusions We conclude that VUI generated in third-generation, dual-source DECT has diagnostic image quality and can replace the CUI in triple-phase studies, with a mean ED reduction by 39%. The VUI obtained from arterial phase is superior to those obtained from portal venous phase.


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