scholarly journals A Case of In Situ Carcinoma of the Gallbladder Associated with Pancreaticobiliary Maljunction

2012 ◽  
Vol 45 (12) ◽  
pp. 1180-1185
Author(s):  
Daisuke Fujimoto ◽  
Shiho Kono ◽  
Takuro Terada ◽  
Takeshi Mitsui ◽  
Yasuni Nakanuma ◽  
...  
2021 ◽  
pp. 106689692110029
Author(s):  
Kerschen Anja ◽  
Dano Hélène ◽  
Van Eeckhout Pascal ◽  
Marot Liliane ◽  
Van Bockstal Mieke

Mammary Paget’s disease accounts for 1% to 3% of all breast tumors and manifests as a chronic eczematous lesion of the areolar skin. It can occur without any underlying neoplasia or can be present in association with an underlying invasive and/or in situ carcinoma of the breast. The present report describes a challenging nipple punch biopsy showing an infiltration of the lower third to two-thirds of the epidermis by large, ovoid, neoplastic cells. The morphology was consistent with mammary Paget's disease, although immunohistochemistry for cytokeratin-7 (CK7) was repeatedly negative. This resulted in an initial misdiagnosis and, subsequently, a delay in the patient's follow-up. Additional immunohistochemistry for GATA binding protein 3 (GATA3) and human epidermal growth factor receptor 2 (HER2), as well as a second opinion of a breast pathologist, resulted in the diagnosis of mammary Paget's disease. The aim of this article is to raise awareness among pathologists and prevent them from misdiagnosing CK7-negative Paget disease of the breast.


2015 ◽  
Vol 23 (4) ◽  
pp. 442-447 ◽  
Author(s):  
Eduardo Augusto ROSA ◽  
Erica Negrini LIA ◽  
Sergio Bruzadelli MACEDO ◽  
Rivadavio Fernandes Batista de AMORIM

1948 ◽  
Vol 56 (2) ◽  
pp. 335-339 ◽  
Author(s):  
Frank W. Foote ◽  
Katherine Li
Keyword(s):  

2013 ◽  
Vol 165 (3-4) ◽  
pp. 319-325 ◽  
Author(s):  
John S. Munday ◽  
Magda Dunowska ◽  
Simon F. Hills ◽  
Rebecca E. Laurie

2021 ◽  
Vol 8 (5) ◽  
pp. 1650
Author(s):  
Subhransu Kumar Hota ◽  
Ranjana Giri ◽  
Hardik Kabra ◽  
Devika Chauhan ◽  
Prita Pradhan ◽  
...  

Breast lumps have diverse causes including benign as well as malignant lesions. Fibroadenoma (FA) is a common cause of breast lump. Complex fibroadenomas, a particular subtype, pose diagnostic dilemmas due to confusing the radiological findings and hold higher incidence of transformation to malignancy. A 49 year old female presented with a painless lump in right breast for 2 years which appeared calcified on radiology. Excision biopsy was performed which grossly revealed an encapsulated grey-white firm to hard with cystic areas. Microscopically the sections showed a well encapsulated fibroepithelial tumor showing areas of sclerosing adenosis, hyalinization, cysts lined by cuboidal cells with eosinophilic secretions, areas of calcification and ossification. No evidence of lobular hyperplasia or in-situ carcinoma was seen. Patient was advised follow up. This case represents the unusual occurrence of complex fibroadenoma in a middle-aged female showing with ossification.


2008 ◽  
Vol 15 (04) ◽  
pp. 455-458
Author(s):  
MUHAMMAD MUMTAZ CHAUDHRY ◽  
SHEHRYAR ALTAF

Objectives: To evaluate 20 patients with squamous cell carcinoma of the conjunctiva. To determine the clinical andpathological characteristics. Design Retrospective study. Setting: POF hospital & EDO eye hospital Wah.Cantt Period: From June 200 toJuly 2006. Methods: The patients presenting with squamous cell carcinoma of the conjunctiva were retrospectively evaluated. Results: Patientswere usually male (80%), elderly (75% >60 years of age), with most lesions (90%) occurring at the limbus. Two patients (10%) sufferedrecurrence of the squamous cell of the conjunctiva within 2 to 4 months of resection. Corneal invasion was noted in two patients (!0%) whilethere was intraocular and orbital invasion in two patients (10%). One patient (5%) required enucleation and one patient (5%) requiredexenteration. In situ carcinoma was noted in 18 patients (90%). Conclusions: Squamous cell carcinoma of the conjunctiva occurs in the sunexposed area of the conjuntiva at the limbus in the elderly men. Recurrence was noted in the younger patients and with larger lesions.Enucleation and exenteration is required in a small number of cases.


1986 ◽  
Vol 56 (4) ◽  
pp. 369-373 ◽  
Author(s):  
Ross C. Smith ◽  
Kenneth Kneale ◽  
Kerry Goulston

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