Abdominal Subcutaneous Nodules With Florid Granulomatous Reaction in a 53-Year-Old Woman

2005 ◽  
Vol 129 (12) ◽  
pp. e206-e208
Author(s):  
Shahrokh Momtahen ◽  
Afshin Salarieh ◽  
Nena Chin
Keyword(s):  
Granulomatous Reaction ◽  
Subcutaneous Nodules

Detection of Sarcoidosis Based on Subcutaneous Nodules in the Dorsum of the Right Hand

2014 ◽  
Vol 76 (1) ◽  
pp. 14-17
Author(s):  
Yoshiyuki KUWAE ◽  
Kunitaka HARUNA ◽  
Yasushi SUGA
Keyword(s):  
Subcutaneous Nodules ◽  
Right Hand ◽  
The Right

scholarly journals Response patterns in adventitial layer of Echinococcus granulosus sensu stricto cysts from naturally infected cattle and sheep

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Christian Hidalgo ◽  
Caroll Stoore ◽  
María Soledad Baquedano ◽  
Ismael Pereira ◽  
Carmen Franco ◽  
...  
Keyword(s):  
Immune Response ◽  
Echinococcus Granulosus ◽  
Cystic Echinococcosis ◽  
Direct Contact ◽  
Sensu Stricto ◽  
Response Patterns ◽  
Granulomatous Reaction ◽  
Adventitial Layer ◽  
Laminated Layer ◽  
Cattle And Sheep

AbstractCystic echinococcosis is a zoonotic disease caused by the metacestode of Echinococcus granulosus sensu lato. The disease is characterized by the development of cystic structures inside viscera of the intermediate host, mainly liver and lungs. These cysts are formed by three layers: germinal, laminated, and adventitial layer, the latter being the local host immune response. Metacestodes that develop protoscoleces, the infective stage to the definitive host, are termed fertile, whereas cysts that do not produce protoscoleces are termed non-fertile. Sheep usually harbor fertile cysts while cattle usually harbor non-fertile cysts. Adventitial layers with fibrotic resolution are associated to fertile cysts, whereas a granulomatous reaction is associated with non-fertile cysts. The aim of this study was to analyze cellular distribution in the adventitial layer of fertile and non-fertile E. granulosus sensu stricto cysts found in liver and lungs of cattle and sheep. A total of 418 cysts were analyzed, 203 from cattle (8 fertile and 195 non-fertile) and 215 from sheep (64 fertile and 151 non-fertile). Fertile cysts from cattle showed mixed patterns of response, with fibrotic resolution and presence of granulomatous response in direct contact with the laminated layer, while sheep fertile cysts always displayed fibrotic resolution next to the laminated layer. Cattle non-fertile cysts display a granulomatous reaction in direct contact with the laminated layer, whereas sheep non-fertile cysts display a granulomatous reaction, but in direct contact with the fibrotic resolution. This shows that cattle and sheep cystic echinococcosis cysts have distinct local immune response patterns, which are associated to metacestode fertility.

Subcutaneous Nodules at Injection Sites: Histopathological Pitfalls in Diagnosis

2008 ◽  
Vol 32 (1) ◽  
pp. 80-80
Author(s):  
I.H. Chaudhry ◽  
H. Chong ◽  
K. Brady ◽  
D. Metze ◽  
E. Calonje
Keyword(s):  
Subcutaneous Nodules

scholarly journals Regulation by Chemokines of Circulating Dendritic Cell Precursors, and the Formation of Portal Tract–Associated Lymphoid Tissue, in a Granulomatous Liver Disease

2000 ◽  
Vol 193 (1) ◽  
pp. 35-50 ◽  
Author(s):  
Hiroyuki Yoneyama ◽  
Kenjiro Matsuno ◽  
Yanyun Zhang ◽  
Masako Murai ◽  
Meiji Itakura ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Lymphoid Tissue ◽  
Propionibacterium Acnes ◽  
Portal Tract ◽  
Lymphoid Organ ◽  
Solid Organ ◽  
Granulomatous Reaction ◽  
Portal Area ◽  
Inflammatory Protein ◽  
Macrophage Inflammatory Protein

We have studied the recruitment and roles of distinct dendritic cell (DC) precursors from the circulation into Propionibacterium acnes–induced granulomas in mouse liver. During infection, F4/80−B220−CD11c+ DC precursors appeared in the circulation, migrated into the perisinusoidal space, and matured within newly formed granulomas. Recruited DCs later migrated to the portal area to interact with T cells in what we term “portal tract–associated lymphoid tissue” (PALT). Macrophage inflammatory protein 1α attracted blood DC precursors to the sinusoidal granuloma, whereas secondary lymphoid organ chemokine (SLC) attracted mature DCs to the newly identified PALT. Anti-SLC antibody diminished PALT expansion while exacerbating granuloma formation. Therefore, circulating DC precursors can migrate into a solid organ like liver, and participate in the granulomatous reaction in response to specific chemokines.

Agammaglobulinemia with polyarthritis and subcutaneous nodules

1970 ◽  
Vol 48 (1) ◽  
pp. 40-47 ◽  
Author(s):  
Eugene V. Barnett ◽  
Alan Winkelstein ◽  
Howard J. Weinberger
Keyword(s):  
Subcutaneous Nodules

scholarly journals Nivolumab-Induced Sarcoid-Like Granulomatous Reaction in a Patient With Advanced Melanoma

CHEST Journal ◽  
2016 ◽  
Vol 149 (5) ◽  
pp. e133-e136 ◽  
Author(s):  
François-Xavier Danlos ◽  
Cécile Pagès ◽  
Barouyr Baroudjian ◽  
Laetitia Vercellino ◽  
Maxime Battistella ◽  
...  
Keyword(s):  
Advanced Melanoma ◽  
Granulomatous Reaction

scholarly journals Periosteal Ganglia Presenting as Subcutaneous Nodules on the Tibia

2014 ◽  
Vol 150 (6) ◽  
pp. 663 ◽  
Author(s):  
Nkanyezi N. Ferguson ◽  
Adam Asarch ◽  
Amanda J. Tschetter ◽  
Mary Stone
Keyword(s):  
Subcutaneous Nodules

scholarly journals Substance P Signaling Contributes to Granuloma Formation inTaenia crassicepsInfection, a Murine Model of Cysticercosis

2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Armandina Garza ◽  
David J. Tweardy ◽  
Joel Weinstock ◽  
Balaji Viswanathan ◽  
Prema Robinson
Keyword(s):  
Substance P ◽  
Potential Role ◽  
Cytokine Production ◽  
Taenia Solium ◽  
Granuloma Formation ◽  
Wild Type ◽  
Granulomatous Reaction ◽  
Pain Transmission ◽  
Neurokinin 1 ◽  
The Brain

Cysticercosis is an infection with larval cysts of the cestodeTaenia solium. Through pathways that are incompletely understood, dying parasites initiate a granulomatous reaction that, in the brain, causes seizures. Substance P (SP), a neuropeptide involved in pain-transmission, contributes to inflammation and previously was detected in granulomas associated with deadT. crassicepscysts. To determine if SP contributes to granuloma formation, we measured granuloma-size and levels of IL-1β, TNF-α, and IL-6 within granulomas inT. crassiceps-infected wild type (WT) mice and mice deficient in SP-precursor (SPP) or the SP-receptor (neurokinin 1, NK1). Granuloma volumes of infected SPP- and NK1-knockout mice were reduced by 31 and 36%, respectively, compared to WT mice (P<.05for both) and produced up to 5-fold less IL-1β, TNF-α, and IL-6 protein. Thus, SP signaling contributes to granuloma development and proinflammatory cytokine production inT. crassicepsinfection and suggests a potential role for this mediator in human cystercercosis.

Subcutaneous Nodules as a Dermatologic Manifestation of Bacteremia Due to Pseudomonas aeruginosa

1994 ◽  
Vol 87 (2) ◽  
pp. 233-235 ◽  
Author(s):  
RAFAEL E. CAMPO ◽  
KENNETH R. RATZAN ◽  
STEVEN J. MELNICK
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Subcutaneous Nodules
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