Multiple tender, erythematous subcutaneous nodules on the lower extremities. Membranous fat necrosis

1993 ◽  
Vol 129 (10) ◽  
pp. 1331b-1331 ◽  
Author(s):  
A. Yen
PEDIATRICS ◽  
1992 ◽  
Vol 90 (1) ◽  
pp. 93-96 ◽  
Author(s):  
JENNIFER S. COOK ◽  
MARY SEABURY STONE ◽  
JAMES R. HANSEN

Subcutaneous fat necrosis of the newborn is an uncommon disorder that occurs during the first few weeks of life as firm subcutaneous nodules on the cheeks, buttocks, back, arms, and thighs. This disorder, which initially was described by Harrison and McNee in 1926,1 typically affects full-term newborns who have experienced perinatal distress. Subcutaneous fat necrosis of the newborn usually resolves over a period of months, but may result in death due to its association with hypercalcemia. The association between subcutaneous fat necrosis of the newborn and hypercalcemia was first reported by Clay in 19562; however, the mechanism that results in hypercalcemia remains incompletely understood.3-7


2006 ◽  
Vol 31 (2) ◽  
pp. 250-251 ◽  
Author(s):  
Deuk Pyo Lee ◽  
Sung Eun Chang

2021 ◽  
Vol 7 (3) ◽  
pp. 264-267
Author(s):  
Samagani Akshay ◽  
Pemmanda Raju Belliappa ◽  
Raveendra Leena

Subcutaneous fat necrosis of newborn is a rare cutaneous disorder affecting neonates. It usually presents as subcutaneous nodules or plaques, within the first few weeks of life, following an eventful delivery. It is characterized by hypercalcemia, which may present with lethargy, irritability, hypotonia and dehydration, mimicking sepsis. Histopathology is proven to be the gold standard in diagnosis with characteristic lobular panniculitis, mixed inflammatory cell infiltrate and radially arranged crystals. This needs to be differentiated from other causes of lobular panniculitis, as early diagnosis and treatment to prevent long‑term complications are advocated. Education of parents regarding the disease and danger signs of hypercalcemia and weekly monitoring of serum calcium is recommended. Treatment based on rehydration, dietary vitamin D and calcium restriction, Furosemide and prednisolone are considered. We have discussed a case of subcutaneous fat necrosis, in an 8-week-old male baby.Key Messages: Subcutaneous fat necrosis is an important differential in neonates presenting with palpable subcutaneous nodules, along with sclerema neonatorum. Severe complications like hypercalcemia should be detected early and managed aggressively to prevent morbidities and mortalities associated with it. Symptomatic management, use of calcium lowering drugs and regular monitoring of calcium levels are recommended.


2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Mitali Sahni ◽  
Pooja Patel ◽  
Akila Muthukumar

Background. Subcutaneous fat necrosis (SFN) is a form of transient panniculitis that presents commonly in infants with a history of perinatal insult, particularly hypothermia. It is characterized by subcutaneous nodules and plaques that appear over bony prominences on cheeks, shoulders, buttock, and thighs. SFN is usually associated with various complications including hypercalcemia, thrombocytopenia, hypertriglyceridemia, and hyperglycemia. Case Presentation. We present a unique case of a female infant with a history of maternal chorioamnionitis who presented with SFN at 11 days of life with thrombocytosis. The platelet count decreased during the hospital stay, and thrombocytosis resolved over the course of the next two weeks. She did not have any other hematological or metabolic abnormalities associated with SFN. Conclusion. Infants with perinatal stress are at increased risk of developing SFN during the first month of life. Infants with a diagnosis of SFN should be monitored closely for various hematological and metabolic abnormalities that can have serious consequences.


2022 ◽  
Vol 13 (1) ◽  
pp. 82-85
Author(s):  
Radia Chakiri ◽  
Youssef Bouhajeb

Pilomatricoma is a benign tumor originating from hair follicle matrix cells and characterized by the presence of cutaneous and subcutaneous nodules up to 3.0 cm in diameter, usually on the head, neck, and upper extremities, rarely on the trunk and lower extremities. An eleven-year-old female with a painless, erythematous-purplish tumor of the back. A dermoscopic examination revealed irregular linear vessels, white structures, and structureless grayish-blue areas. Histological examination after excision confirmed the diagnosis of pilomatricoma. Dermoscopy may be a useful tool for improving the clinical recognition of pilomatricoma.


2005 ◽  
Vol 31 (2) ◽  
pp. 250-251 ◽  
Author(s):  
DEUK PYO LEE ◽  
SUNG EUN CHANG

Sign in / Sign up

Export Citation Format

Share Document