Current status of human immunodeficiency virus and hepatitis C virus (HIV/HCV) co-infection in Cameroon: Sero-prevalence, risk factors and correlation with markers of liver function and CD4 cells rate in patients diagnosed in three hospital settings

Human Immunodeficiency virus (HIV), Hepatitis B virus (HBV), Hepatitis C virus (HCV) and Syphilis infection are the major public health problem, alarming the most developing countries like Bangladesh. These studies determined the prevalence rate and risk factors of HIV, Hepatitis B, Hepatitis C and Syphilis among nonprofessional blood donors in multiple blood transfusion center of Chittagong. Information was collected by questionnaire to find out the relationship of HIV, HBV, HCV and Syphilis infection with age, sex, socioeconomic status, residence and religious believes. The sero-prevalence of HIV, HBsAg (HBV), anti-HCV (HCV), VDRL (Syphilis) among the non-professional blood donors were 00.00%, 4.88%, 0.92%, and 0.70% respectively. So, the highest prevalence rate was HBsAg and the lowest was HIV. We didnt find more than one positive case in the same blood sample. The prevalence of HBsAg among the study population, students (120/6) were 5.00%, service holders (73/3) were 4.11%, businessmen (40/4) were 10%, housewives (14/0) were 00.00%, others (farmers, immigrant workers) (40/1) were 2.50%. The highest prevalence of HBsAg was due to illiteracy and unsafe sexual behaviors.Asian J. Med. Biol. Res. December 2015, 1(3): 518-525

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Transmission of hepatitis C virus to infants of human immunodeficiency virus-negative intravenous drug-using mothers: rate of infection and assessment of risk factors for transmission

Journal of Viral Hepatitis ◽

10.1046/j.1365-2893.1997.00073.x ◽

1997 ◽

Vol 4 (6) ◽

pp. 395-409 ◽

Cited By ~ 82

Author(s):

J. D. Spencer ◽

N. Latt ◽

P. J. Beeby ◽

E. Collins ◽

J. B. Saunders ◽

...

Keyword(s):

Risk Factors ◽

Human Immunodeficiency Virus ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Intravenous Drug ◽

Immunodeficiency Virus

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Prevalence and risk factors of hepatitis C virus, hepatitis B virus, and human immunodeficiency virus in multiply transfused recipients in Mexico

Transfusion ◽

10.1111/j.1537-2995.2009.02248.x ◽

2009 ◽

Vol 49 (10) ◽

pp. 2200-2207 ◽

Cited By ~ 9

Author(s):

Gloria M. Calderón ◽

Felipe González-Velázquez ◽

Cesar R. González-Bonilla ◽

Bárbara Novelo-Garza ◽

Jose J. Terrazas ◽

...

Keyword(s):

Risk Factors ◽

Human Immunodeficiency Virus ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Hepatitis B Virus ◽

Hepatitis B ◽

Virus Hepatitis ◽

B Virus ◽

Immunodeficiency Virus

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Seroprevalence of Hepatitis B, Hepatitis C and Human Immunodeficiency Virus Among Multitransfused Thalassaemic Children in Dhaka, Bangladesh

Bangladesh Journal of Child Health ◽

10.3329/bjch.v37i3.18618 ◽

2014 ◽

Vol 37 (3) ◽

pp. 146-153 ◽

Cited By ~ 2

Author(s):

AKM Rezaul Karim ◽

Afiqul Islam ◽

Choudhury Yakub Jamal ◽

Abdul Matin ◽

Md Monir Hossain ◽

...

Keyword(s):

Risk Factors ◽

Human Immunodeficiency Virus ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Hepatitis B Virus ◽

Hepatitis B ◽

Transmitted Infection ◽

Transfusion Transmitted Infection ◽

B Virus ◽

Immunodeficiency Virus

Background: Thalassaemia is a congenital hemolytic disease caused by defective globin chain synthesis of haemoglobin and largely treated by repeated blood transfusions. Transfusion-transmitted infections still make a great challenge in the management of patients with thalassaemia major. The most important worldwide transfusion transmitted infections (TTI) are hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV). Despite concern about a possible increase in the incidence of these infections there are no recent data about the prevalence of HBV, HCV and HIV from Bangladesh. Objectives: To evaluate the prevalence of hepatitis B, hepatitis C and human immunodeficiency virus in multi-transfused thalassaemia patients (MTP), to identify the possible risk factors and to evaluate the effect of compulsory screening of blood to prevent these infections. Methodology: This cross-sectional study was conducted during 2011 to 2012 on 100 consecutive multi-transfused thalassaemic patients who were interviewed using a structured questionnaire and tested for serological markers of hepatitis B virus (HBsAg), hepatitis C virus (Anti-HCV) and human immunodeficiency virus (Anti-HIV 1+2). Results: The overall prevalence of HCV, HBV, HIV and co-infection among (MTP) were 31%, 3%, 0% and 1%, respectively. Children who developed infection had a higher incidence of receiving transfusion from professional donors or unknown donors than the non-infected ones. Infected children had a higher frequency of receiving transfusions without screening and receiving more number of transfusions than their counterpart. Other non-transfusion related (NTR) risk factors such as surgical operation, dental procedures, needle stick injury were significantly higher in patients who acquired transfusion transmitted infections (TTI). Conclusions: HCV infection was the most prevalent transfusion transmitted infection (TTI) among multi-transfused thalassaemia patients (MTP) and remains a major health problem for these patients. Children who received transfusion from professional donors and received unscreened blood had more chance of getting infection with transfusion transmitted infection. DOI: http://dx.doi.org/10.3329/bjch.v37i3.18618 Bangladesh J Child Health 2013; Vol.37(3): 146-153

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