scholarly journals Diversity and anticancer activity of endophytic fungi associated with the medicinal plant Saraca asoca

2015 ◽  
Vol 5 (3) ◽  
pp. 169-179 ◽  
Author(s):  
MV Jinu
Symbiosis ◽  
2012 ◽  
Vol 57 (2) ◽  
pp. 95-107 ◽  
Author(s):  
Camila R. Carvalho ◽  
Vivian N. Gonçalves ◽  
Cristiane B. Pereira ◽  
Susana Johann ◽  
Isis V. Galliza ◽  
...  

Author(s):  
Fatma Khuseib Hamed Al-Rashdi ◽  
Abdullah Mohammed Al-Sadi ◽  
Bahja Z. Al-Riyamy ◽  
Sajeewa S.N. Maharachchikumbura ◽  
Jamal Nasser Al-Sabahi ◽  
...  

Symbiosis ◽  
2011 ◽  
Vol 53 (2) ◽  
pp. 89-95 ◽  
Author(s):  
Virginia Medeiros de Siqueira ◽  
Raphael Conti ◽  
Janete Magali de Araújo ◽  
Cristina Maria Souza-Motta

2009 ◽  
Vol 64 (7-8) ◽  
pp. 518-520 ◽  
Author(s):  
Yin Lu ◽  
Shaoyuan Chen ◽  
Ben Wang

Eleven strains of endophytic fungi which habitat in an endangered, Chinese endemic medicinal plant, Dysosma pleiantha (Hance) Woodson, were isolated and tested for their cytotoxic activity using the brine shrimp lethality bioassay. Six isolates were found to exhibit some cytotoxic activity. Extracts of F1273, F1276, and F1280, which were identified as Trichoderma citrinoviride, Chaetomium globosum and Ascomycete sp., in particular, showed most potent activity with LC50 values of 4.86, 7.71, and 14.88 μg/ml, respectively. These results indicate that endophytic fungi of Dysosma pleiantha could be a promising source for antitumour agents.


2018 ◽  
Vol 15 (4) ◽  
pp. 887-898
Author(s):  
V. Antony Jenila ◽  
J. Joel Gnanadoss

Endophytic fungi Fusarium sp. LCJ273 capable of producing L-asparaginase was isolated from the medicinal plant Adhatoda vasica. The aim of the present study was to maximize L-asparaginase production by submerged fermentation through statistical optimization. L-Asparaginase production by Fusarium sp. LCJ273 was studied in five different media. Various nutritional parameters specifically carbon, nitrogen and inducers were optimized for enhancing the production of L-asparaginase. In addition, different statistical based experimental designs were also applied to increase the production of L-asparaginase by Fusarium sp. LCJ273. Dextrose, ammonium sulphate and wheat bran were found to be effective for growth and higher yield of L-asparaginase in Modified Czapek’s Dox Broth. Dextrose at a concentration of 3.0 g/L increased L-asparaginase production up to 9.18±0.9 U/mL, ammonium sulphate at the concentration of 20 g/L showed maximum L-asparaginase production up to 13.69±0.4 U/mL and wheat bran at 2.5 g/L yielded up to 14.24±0.5 U/mL. The maximum L-asparaginase production was observed by Fusarium sp. LCJ273 on 5th day. The study revealed that through optimization, a 2 fold increase in L-asparaginase could be achieved.


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