Development and Validation of Spectrophotometric Determination of Glimepiride in Pure and Tablet Dosage forms through Ion-Pair Complex Formation using Bromothymol Blue

2018 ◽  
Vol 11 (7) ◽  
pp. 3049
Author(s):  
Abdul Aziz Ramadan ◽  
Souad Zeino
2019 ◽  
Vol 17 (72) ◽  
pp. 93-100
Author(s):  
Kawther A. Sadeq

A new simple spectrophotometric method based on the formation of an ion –pair using bromothymol blue as ion –pair complexion reagent was developed for the determination of ciprofloxacin in pure form and  tablets . Theion-pair formed was highly colored and easily extracted with chloroform at (pH3.0) and determined spectrophotometrically at 421 nm .The proposed method was successfully applied to determine (CPF) in its tablet formulation and the results are good , No interferences from an effective addition were noticed .


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