Synthesis, Characterization and Antimicrobial Evaluation of Novel Schiff Bases of Aryl Amines Based 2-Azetidinones and 4-Thiazolidinones

2020 ◽  
Vol 13 (1) ◽  
pp. 168
Author(s):  
Kamala Govindarao ◽  
N. Srinivasan ◽  
R. Suresh
Keyword(s):  
Schiff Bases ◽  
Aryl Amines ◽  
Antimicrobial Evaluation

scholarly journals Microwave Assisted Synthesis and Antimicrobial Evaluation of Schiff Bases of Indole-3-aldehyde

2011 ◽  
Vol 8 (1) ◽  
pp. 305-311 ◽  
Author(s):  
Priyanka Kamaria ◽  
N. Kawathekar ◽  
Prerna Chaturvedi
Keyword(s):  
Schiff Bases ◽  
Antimicrobial Agents ◽  
Microwave Assisted Synthesis ◽  
Bacterial Strains ◽  
Mass Spectral Analysis ◽  
Gram Positive ◽  
Gram Negative ◽  
Mass Spectral ◽  
Microwave Assisted ◽  
Antimicrobial Evaluation

In order to develop new antimicrobial agents, a series of Schiff bases of indole-3-aldehyde were synthesized by microwave assisted synthesis by takingDMFas solvent and evaluated for their antimicrobial activity. All the synthesized compounds were characterized byIR,1HNMRand mass spectral analysis. All compounds were tested against five gram positive and five gram negative bacterial strains and one fungal strain. All compounds exhibited better activity against gram positive strains than against gram negative strains and the compounds were found more active againstS.aureusandB.subtilis.

scholarly journals Synthesis, Characterization and Antimicrobial Evaluation of Schiff’s Base and Aryl Aminomethyl Derivatives

2016 ◽  
Vol 64 ◽  
pp. 89-94
Author(s):  
N.N. Kansagara ◽  
V.R. Dangar ◽  
V.R. Shah
Keyword(s):  
Selective Reduction ◽  
Schiff’S Bases ◽  
Schiff’S Base ◽  
Chemical Structures ◽  
Imine Group ◽  
Schiff's Bases ◽  
Aminomethyl Derivatives ◽  
Aryl Amines ◽  
Antimicrobial Evaluation ◽  
Antibacterial And Antifungal

Schiff’s bases are obtained on heating an aldehydes with aromatic amine in presence of glacial acetic acid. These are the compounds containing characteristic –HC=N– group. Aryl amino methyl derivatives of heterocyclic compounds to synthesize by selective reduction of schiff’s bases (imine group) with sodiumborohydride in controlled experimental condition. Schiff’s base of N-Aryl-1-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]methanimines & Aryl amines of N-Aryl-1-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]methanamines were prepared. Their chemical structures were confirmed by means of IR, NMR, Mass data and by elemental analysis. All of the synthesized compounds were tested for their antibacterial and antifungal activity.

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