Traditional condition monitoring methods are not suitable for the nonlinear operation parameters and time-variable operation conditions. We propose an independent component analysis method based on sliding window statistics (SSWICA). This method uses statistics in sliding windows of parameters as input samples, then uses a N-step forward sliding window ICA method to modeling. Then we monitor the operating state of the equipments by observing whether the SPE index of real-time parameters exceeds the control limits. SSWICA is applied to condition monitoring of condenser in 600MW unit, comparing with traditional ICA monitoring methods based on sliding window. The results show SSWICA can accurately reflect current operating state and related changes of condensers state parameters, recognize steady, unsteady and fault conditions effectively. It is valuable for engineering practice and suitable for the application to equipments condition monitoring in power plant.