scholarly journals Design, Synthesis and Gene Transfection Activity of Macrocyclic Polyamine-Imidazolium Based Cationic Lipids

2013 ◽  
Vol 71 (04) ◽  
pp. 585
Author(s):  
Yun Fu ◽  
Haijiao Wang ◽  
Ji Zhang ◽  
Xiaoqi Yu
Keyword(s):  
Gene Transfection ◽  
Cationic Lipids ◽  
Macrocyclic Polyamine ◽  
Design Synthesis

α‐Tocopherol‐Conjugated, Open Chain Sugar‐Mimicking Cationic Lipids: Design, Synthesis and In–Vitro Gene Transfection Properties

2021 ◽  
Vol 6 (46) ◽  
pp. 13025-13033
Author(s):  
Venkatesh Ravula ◽  
Venkanna Muripiti ◽  
Shireesha Manthurthi ◽  
Srilakshmi V. Patri
Keyword(s):  
Gene Transfection ◽  
Cationic Lipids ◽  
Open Chain ◽  
Design Synthesis

Hydroxyl-containing non-viral lipidic gene vectors with macrocyclic polyamine headgroups

RSC Advances ◽  
2015 ◽  
Vol 5 (73) ◽  
pp. 59417-59427 ◽  
Author(s):  
Hai-Jiao Wang ◽  
Xi He ◽  
Yang Zhang ◽  
Ji Zhang ◽  
Yan-Hong Liu ◽  
...  
Keyword(s):  
Gene Transfection ◽  
Structure Activity Relationship ◽  
Cationic Lipids ◽  
Activity Relationship ◽  
Macrocyclic Polyamine ◽  
Structure Activity ◽  
Gene Vectors ◽  
Relationship Of

The gene transfection abilities and structure–activity relationship of the newly designed hydroxyl-containing cationic lipids were studied in detail.

Synthesis and gene transfection activity of cyclen-based cationic lipids with asymmetric acyl-cholesteryl hydrophobic tails

2014 ◽  
Vol 12 (21) ◽  
pp. 3484-3492 ◽  
Author(s):  
Bao-Quan Liu ◽  
Wen-Jing Yi ◽  
Ji Zhang ◽  
Qiang Liu ◽  
Yan-Hong Liu ◽  
...  
Keyword(s):  
Gene Transfection ◽  
Cationic Lipids ◽  
Viral Gene ◽  
Gene Vectors

Novel cyclen-based cationic lipids with asymmetric acyl-cholesteryl hydrophobic tails were synthesized and applied as non-viral gene vectors.

scholarly journals Ionic liquids with thioether motifs as synthetic cationic lipids for gene delivery

2017 ◽  
Vol 53 (59) ◽  
pp. 8328-8331 ◽  
Author(s):  
Jamie C. Gaitor ◽  
Lauren M. Paul ◽  
Melissa M. Reardon ◽  
Taha Hmissa ◽  
Samuel Minkowicz ◽  
...  
Keyword(s):  
Ionic Liquids ◽  
Gene Delivery ◽  
Click Chemistry ◽  
Gene Transfection ◽  
Cationic Lipids ◽  
Efficient Gene

Novel lipidic ionic liquids with imidazolium headgroups (red), thioether linkers (black), and two hydrophobic tails (blue) as efficient gene transfection vectors, synthesized via thiol–yne click chemistry.

Dramatic influence of the hydroxy functionality of azasugar moiety in the head group region of tocopherol-based cationic lipids on in vitro gene transfection efficacies

2021 ◽  
Author(s):  
Venkanna Muripiti ◽  
Brijesh Lohchania ◽  
Venkatesh Ravula ◽  
Shireesha Manturthi ◽  
Srujan Marepally ◽  
...  
Keyword(s):  
Gene Transfection ◽  
Cationic Lipids ◽  
Head Group ◽  
Nonviral Vectors

Cationic lipids have been effectively used as nonviral vectors for the delivery of polynucleic acids into the cytosol.

Cationic lipids derived from glycine betaine promote efficient and non-toxic gene transfection in cultured hepatocytes

2002 ◽  
Vol 4 (4) ◽  
pp. 415-427 ◽  
Author(s):  
David Gilot ◽  
Marie-Laure Miramon ◽  
Thierry Benvegnu ◽  
Vincent Ferrieres ◽  
Olivier Loreal ◽  
...  
Keyword(s):  
Glycine Betaine ◽  
Gene Transfection ◽  
Cationic Lipids ◽  
Cultured Hepatocytes ◽  
Toxic Gene

A naphthalimide-based [12]aneN3 compound as an effective and real-time fluorescence tracking non-viral gene vector

2015 ◽  
Vol 51 (93) ◽  
pp. 16695-16698 ◽  
Author(s):  
Yong-Guang Gao ◽  
You-Di Shi ◽  
Ying Zhang ◽  
Jing Hu ◽  
Zhong-Lin Lu ◽  
...  
Keyword(s):  
Real Time ◽  
Organic Molecule ◽  
Gene Transfection ◽  
Viral Gene ◽  
Gene Vector ◽  
Macrocyclic Polyamine ◽  
Small Organic Molecule

A small organic molecule containing naphthalimide and macrocyclic polyamine 12[ane]N3 moieties showed effective and fluorescence tracking gene transfection properties.

Design, synthesis and in vitro evaluation ofd-glucose-based cationic glycolipids for gene delivery

2016 ◽  
Vol 14 (5) ◽  
pp. 1611-1622 ◽  
Author(s):  
Chengxi He ◽  
Shang Wang ◽  
Meiyan Liu ◽  
Chunyan Zhao ◽  
Shuanglin Xiang ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Gene Transfection ◽  
Design Synthesis ◽  
In Vitro Evaluation

Two novel series of cationic cyclic glycolipids were synthesized and the gene transfection efficiencies of these glycolipids were investigeted.

Cationic niosomes composed of spermine-based cationic lipids mediate high gene transfection efficiency

2012 ◽  
Vol 20 (9) ◽  
pp. 783-792 ◽  
Author(s):  
Orapan Paecharoenchai ◽  
Nattisa Niyomtham ◽  
Tanasait Ngawhirunpat ◽  
Theerasak Rojanarata ◽  
Boon-ek Yingyongnarongkul ◽  
...  
Keyword(s):  
Transfection Efficiency ◽  
Gene Transfection ◽  
Cationic Lipids ◽  
High Gene ◽  
Cationic Niosomes
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