Synthesis ofN-4-Pyridyl Amide Derivatives ofN-Diisopropyloxyphosphoryl Amino Acids and Antidotal Activity of Tetrodotoxin (TTX)

2012 ◽  
Vol 32 (1) ◽  
pp. 178
Author(s):  
Hua Fang ◽  
Weizhu Chen ◽  
Bihong Hong ◽  
Yiping Zhang ◽  
Ruizao Yi
Keyword(s):  
Amino Acids ◽  
Amide Derivatives ◽  
Antidotal Activity

ChemInform Abstract: Synthetically Amenable Amide Derivatives of Tosylated-Amino Acids as Organocatalysts for Enantioselective Allylation of Aldehydes: Computational Rationale for Enantioselectivity.

ChemInform ◽  
2013 ◽  
Vol 44 (39) ◽  
pp. no-no
Author(s):  
Debashis Ghosh ◽  
Debashis Sahu ◽  
S. Saravanan ◽  
Sayed H. R. Abdi ◽  
Bishwajit Ganguly ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amide Derivatives ◽  
Derivatives Of

scholarly journals N-Acyl Amino Acids: Metabolism, Molecular Targets, and Role in Biological Processes

Biomolecules ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 822 ◽  
Author(s):  
Natalia Battista ◽  
Monica Bari ◽  
Tiziana Bisogno
Keyword(s):  
Amino Acids ◽  
Therapeutic Potential ◽  
Current Knowledge ◽  
Acid Amide ◽  
Molecular Targets ◽  
Naturally Occurring ◽  
Lipid Signal ◽  
Amide Derivatives

The lipid signal is becoming increasingly crowded as increasingly fatty acid amide derivatives are being identified and considered relevant therapeutic targets. The identification of N-arachidonoyl-ethanolamine as endogenous ligand of cannabinoid type-1 and type-2 receptors as well as the development of different–omics technologies have the merit to have led to the discovery of a huge number of naturally occurring N-acyl-amines. Among those mediators, N-acyl amino acids, chemically related to the endocannabinoids and belonging to the complex lipid signaling system now known as endocannabinoidome, have been rapidly growing for their therapeutic potential. Here, we review the current knowledge of the mechanisms for the biosynthesis and inactivation of the N-acyl amino acids, as well as the various molecular targets for some of the N-acyl amino acids described so far.

Synthetically amenable amide derivatives of tosylated-amino acids as organocatalysts for enantioselective allylation of aldehydes: computational rationale for enantioselectivity

2013 ◽  
Vol 11 (21) ◽  
pp. 3451 ◽  
Author(s):  
Debashis Ghosh ◽  
Debashis Sahu ◽  
S. Saravanan ◽  
Sayed H. R. Abdi ◽  
Bishwajit Ganguly ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amide Derivatives ◽  
Derivatives Of
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