scholarly journals Synthesis and Biological Activity of Novel Chalcone Derivatives Containing 2-Substituted-1,3-thiazolidine Ring

2012 ◽  
Vol 32 (9) ◽  
pp. 1690
Author(s):  
Hong Dai ◽  
Wenke Miao ◽  
Jianbing Liu ◽  
Shanshan Wu ◽  
Xue Qin ◽  
...  
Keyword(s):  
Biological Activity ◽  
Chalcone Derivatives ◽  
Thiazolidine Ring

scholarly journals Biological activity screening of some hydrazone and chalcone derivatives

2021 ◽  
Vol 78 (2) ◽  
pp. 159-166
Author(s):  
Begüm Evranos Aksöz ◽  
Fatma Kaynak-Onurdag ◽  
Erkan Aksoz ◽  
Selda Özgen Özgacar
Keyword(s):  
Biological Activity ◽  
Chalcone Derivatives ◽  
Activity Screening

Synthesis, Biological Activity and Action Mechanism Study of Novel Chalcone Derivatives Containing Malonate

2020 ◽  
Vol 17 (4) ◽  
Author(s):  
Tao Guo ◽  
Rongjiao Xia ◽  
Tingting Liu ◽  
Feng Peng ◽  
Xuemei Tang ◽  
...  
Keyword(s):  
Biological Activity ◽  
Mechanism Study ◽  
Action Mechanism ◽  
Chalcone Derivatives

scholarly journals Cytotoxicity Assay of 2,4-Dihydroxide-4’-Methoxychalcone Against Cervical (HeLa) Cancer Cell by MTT Assay

Biota ◽  
2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Novia Suryani ◽  
Sabirin Matsjeh ◽  
Mutmainah Mutmainah ◽  
Daratu Eviana Kusuma Putri Eviana Kusuma Putri ◽  
Damayanti Iskandar ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Biological Activity ◽  
Hela Cell ◽  
Cancer Cell ◽  
Mtt Assay ◽  
Antibacterial Activities ◽  
Target Compound ◽  
Chalcone Derivatives ◽  
Chalcone Derivative ◽  
Phenolic Group

Chalcone is one of the phenolic group secondary metabolic with numerous biological activity. Many studies have shown that chalcone derivatives compound has anticancer, anti-inflammatory, antimalarial, and antibacterial activities. The purpose of this research was to study the prediction potency unsaturated carbonyl system of chalcone derivative against the HeLa cell by MTT assay. Those activities assumed can inhibit the mechanism action of NF-kB that caused cervical cancer. The 2,4-dihydroxide-4’-methoxychalcone has done synthesis as a target compound by a sonochemical for 7 hours. The results showed that chalcone derivative most active against the HeLa cell.  

Design, synthesis, biological activity and structure-activity relationship studies of chalcone derivatives as potential anti-Candida agents

2018 ◽  
Vol 71 (8) ◽  
pp. 702-712 ◽  
Author(s):  
Jéssica T. Andrade ◽  
Felipe R. S. Santos ◽  
William G. Lima ◽  
Carla D. F. Sousa ◽  
Lohanna S. F. M. Oliveira ◽  
...  
Keyword(s):  
Biological Activity ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Design Synthesis ◽  
Chalcone Derivatives ◽  
Structure Activity

scholarly journals Biological activity evaluation and action mechanism of chalcone derivatives containing thiophene sulfonate

RSC Advances ◽  
2019 ◽  
Vol 9 (43) ◽  
pp. 24942-24950 ◽  
Author(s):  
Tao Guo ◽  
Rongjiao Xia ◽  
Mei Chen ◽  
Jun He ◽  
Shijun Su ◽  
...  
Keyword(s):  
Biological Activity ◽  
Action Mechanism ◽  
Chalcone Derivatives ◽  
Activity Evaluation ◽  
Antiviral Activities

Synthesis, antibacterial, antiviral activities and action mechanism of chalcone derivatives containing thiophene sulfonate.

scholarly journals Structural Characterization of Two Novel, Biological Active Chalcone Derivatives, Using Density Functional Theory Studies

2021 ◽  
Vol 11 (6) ◽  
pp. 15051-15057
Keyword(s):  
Density Functional Theory ◽  
Biological Activity ◽  
Density Functional ◽  
Anticancer Agent ◽  
Functional Theory ◽  
Chalcone Derivatives ◽  
Computational Evaluation ◽  
Structural Evaluation ◽  
Prenylated Chalcone

Xanthohumol is a prenylated chalcone derived from hops and very well known for its biological activity as an anticancer agent. We have previously reported a complete computational evaluation of two novel chalcone derivatives, substituted with diethanolamine on the second ring with increased biological activity. Herein, using density functional theory studies, we are representing a complete structural evaluation of these two molecules. It seems that the significant alterations on their spectroscopic data are responsible for their higher biological activity.

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