scholarly journals Highly sensitive magnetic particle imaging of vulnerable atherosclerotic plaque with active myeloperoxidase-targeted nanoparticles

Theranostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 506-521
Author(s):  
Wei Tong ◽  
Hui Hui ◽  
Wenting Shang ◽  
Yingqian Zhang ◽  
Feng Tian ◽  
...  

ACS Nano ◽  
2017 ◽  
Vol 11 (12) ◽  
pp. 12067-12076 ◽  
Author(s):  
Elaine Y. Yu ◽  
Prashant Chandrasekharan ◽  
Ran Berzon ◽  
Zhi Wei Tay ◽  
Xinyi Y. Zhou ◽  
...  


Nanoscale ◽  
2017 ◽  
Vol 9 (47) ◽  
pp. 18723-18730 ◽  
Author(s):  
Hamed Arami ◽  
Eric Teeman ◽  
Alyssa Troksa ◽  
Haydin Bradshaw ◽  
Katayoun Saatchi ◽  
...  

The first study of Magnetic Particle Imaging (MPI) for tomographic imaging of cancer targeted iron oxide nanoparticles.





Author(s):  
K Them ◽  
J Salamon ◽  
M Kaul ◽  
C Lange ◽  
H Ittrich ◽  
...  


Author(s):  
S Herz ◽  
P Vogel ◽  
D Philipp ◽  
T Kampf ◽  
J Kunz ◽  
...  


2019 ◽  
Author(s):  
P Dietrich ◽  
P Vogel ◽  
M Rückert ◽  
T Bley ◽  
S Herz


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dennis Pantke ◽  
Florian Mueller ◽  
Sebastian Reinartz ◽  
Fabian Kiessling ◽  
Volkmar Schulz

AbstractChanges in blood flow velocity play a crucial role during pathogenesis and progression of cardiovascular diseases. Imaging techniques capable of assessing flow velocities are clinically applied but are often not accurate, quantitative, and reliable enough to assess fine changes indicating the early onset of diseases and their conversion into a symptomatic stage. Magnetic particle imaging (MPI) promises to overcome these limitations. Existing MPI-based techniques perform velocity estimation on the reconstructed images, which restricts the measurable velocity range. Therefore, we developed a novel velocity quantification method by adapting the Doppler principle to MPI. Our method exploits the velocity-dependent frequency shift caused by a tracer motion-induced modulation of the emitted signal. The fundamental theory of our method is deduced and validated by simulations and measurements of moving phantoms. Overall, our method enables robust velocity quantification within milliseconds, with high accuracy, no radiation risk, no depth-dependency, and extended range compared to existing MPI-based velocity quantification techniques, highlighting the potential of our method as future medical application.



Sign in / Sign up

Export Citation Format

Share Document