scholarly journals Glutathione improves the prognosis of Intrauterine Growth Restriction via downregulated hepatic and renal TNFα expression in Wistar rats

2021 ◽  
Author(s):  
Margaret ALESE ◽  
Philemon SHALLİE ◽  
Olawande BAMİSİ
Keyword(s):  
Intrauterine Growth Restriction ◽  
Wistar Rats ◽  
Growth Restriction ◽  
Intrauterine Growth

No association between periodontitis, preterm birth, or intrauterine growth restriction: experimental study in Wistar rats

2016 ◽  
Vol 214 (6) ◽  
pp. 749.e1-749.e11 ◽  
Author(s):  
Mariana Fampa Fogacci ◽  
Davi da Silva Barbirato ◽  
Cristine da Silva Furtado Amaral ◽  
Priscilla Gonçalves da Silva ◽  
Mariana de Oliveira Coelho ◽  
...  
Keyword(s):  
Experimental Study ◽  
Preterm Birth ◽  
Intrauterine Growth Restriction ◽  
Wistar Rats ◽  
Growth Restriction ◽  
Intrauterine Growth

Pathological features of the sequence in pregnant women with delayed fetal growth

2019 ◽  
pp. 50-54
Author(s):  
V.O. Golyanovskiy ◽  
◽  
Ye.O. Didyk ◽  
Keyword(s):  
Pregnant Women ◽  
Intrauterine Growth Restriction ◽  
Normal Development ◽  
Intrauterine Infection ◽  
Normal Pregnancy ◽  
Growth Restriction ◽  
Control Group ◽  
Intrauterine Growth ◽  
Increased Risk ◽  
Infection And Inflammation

Pregnant women with intrauterine growth restriction (IUGR) have an increased risk of adverse perinatal and long-term complications compared with the birth of children with normal body weight. Thus, IUGR is one of the main challenges for the global health system, especially in poor and developing countries. Morpho-functional studies of the placentas help in determining the causes of IUGR, and therefore, timely prevent complications in pregnant women with IUGR. The objective: The purpose of this study is to investigate various morphometric and pathomorphological changes in the placenta, including inflammatory, in cases of IUGR, and to establish a correlation of these results with the etiology and complications for the fetus. Materials and methods. In the current study, 54 placentas of the fetuses with IUGR (the main group) were compared with 50 placentas of the fetuses with normal development (control group). The criteria for the inclusion of IUGR were gestational age more than 30 weeks and all fetuses with a weight less than 10th percentile for this period of pregnancy. The placenta material was studied pathomorphologically with laboratory screening for infection and inflammation. Similarly, the results were determined for placentas of the fetuses with normal development compared to placentas with IUGR. Results. The placenta study showed the presence of calcification in the case of IUGR, as well as in the case of prolonged pregnancy. However, calcification of the placenta in the case of IUGR was more progressive compared with placenta in the normal pregnancy. In addition, the presence of intrauterine infection and inflammation was observed, which could also lead to an adverse outcome for the further progression of pregnancy with IUGR. Conclusion. A comparative macro- and microscopic pathomorphological study of the placentas in the two groups has shown a significant increase in the pathological changes in all the anatomical structures of the fetuses with IUGR. Key words: Intrauterine growth restriction (IUGR), fetal weight, pathomorphological changes of the placenta.

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