scholarly journals Relations Between Cognitive Functioning and Alcohol Use, Craving, and Post-Traumatic Stress: An Examination Among Trauma-Exposed Military Veterans With Alcohol Use Disorder

2016 ◽  
Vol 181 (7) ◽  
pp. 663-671 ◽  
Author(s):  
Adrienne J. Heinz ◽  
David L. Pennington ◽  
Nicole Cohen ◽  
Brandi Schmeling ◽  
Brooke A. Lasher ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Cognitive Functioning ◽  
Traumatic Stress ◽  
Alcohol Use Disorder ◽  
Military Veterans ◽  
Post Traumatic Stress ◽  
Post Traumatic

Post-traumatic stress disorder and alcohol use disorder

2002 ◽  
Vol 8 (2) ◽  
pp. 55-61 ◽  
Author(s):  
I. Roncevic-Grzeta ◽  
Lj. Moro ◽  
T. Franciskovic ◽  
T. Ruzic ◽  
B. Smokvina ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Alcohol Use Disorder ◽  
Stress Disorder ◽  
Post Traumatic Stress ◽  
Post Traumatic

scholarly journals Effect of Selective Serotonin Reuptake Inhibitors on Healthcare Utilization in Patients with Post-Traumatic Stress Disorder and Alcohol Use Disorder

2019 ◽  
Vol 54 (4) ◽  
pp. 428-434 ◽  
Author(s):  
Andrew C Naglich ◽  
Sara Bozeman ◽  
E Sherwood Brown ◽  
Bryon Adinoff
Keyword(s):  
Alcohol Use ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Serotonin Reuptake ◽  
Alcohol Use Disorder ◽  
Stress Disorder ◽  
Selective Serotonin ◽  
Post Traumatic Stress ◽  
Ptsd Diagnosis ◽  
Post Traumatic

Abstract Aims The objective of this study is to address equivocation in estimates of selective serotonin reuptake inhibitor initiation (SSRI) effect on all-cause and alcohol-related ER visits, and medical or psychiatric admissions within 2 years of initial Post-Traumatic Stress Disorder (PTSD) diagnosis in patients with PTSD and Alcohol Use Disorder (AUD). Methods This study is a quasi-experimental, new-user-design cohort study of 3235 patients seen at the VA North Texas Healthcare System between January 1, 2000 and December 31, 2016. High dimensional propensity score (HDPS) techniques were used to estimate likelihood of SSRI initiation within 30 days of first PTSD diagnosis. Propensity scores were used to calculate weights for likelihood of SSRI initiation which were used to control for baseline covariates in estimations of SSRI medication effect on odds of each outcome occurring. Results Compared to those who did not receive SSRIs, patients prescribed an SSRI within 30 days showed significantly lower odds of alcohol-related ER visits (OR=0.668, 95%CI = 0.476 to 0.938, P = 0.02) and alcohol-related medical admissions (OR=0.583, 95%CI = 0.399 to 0.851, P = 0.005). Limitations Inconsistent assessment of PTSD severity necessitated the use of HDPS models to control for baseline confounding. Our study design mimicked intent-to-treat trial design and therefore could not control for SSRI initiations after the 30-day grace period following initial PTSD diagnosis. Conclusions SSRI initiation in patients with AUD and PTSD is associated with significantly reduced odds of alcohol-related medical hospitalization and alcohol-related ER visits within 2 years of first PTSD diagnosis. Additional studies are needed to verify these results.

scholarly journals Post-traumatic stress disorder among persons with HIV who engage in heavy alcohol consumption in southwestern Uganda

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Allen Kekibiina ◽  
Julian Adong ◽  
Robin Fatch ◽  
Nneka I. Emenyonu ◽  
Kara Marson ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Traumatic Stress ◽  
Ptsd Symptoms ◽  
Post Traumatic Stress ◽  
Heavy Alcohol ◽  
Symptoms Of Depression ◽  
Heavy Alcohol Consumption ◽  
Heavy Alcohol Use ◽  
Post Traumatic ◽  
Living With Hiv

Abstract Background We aimed to describe the prevalence of PTSD symptoms and its associated factors in persons living with HIV (PLWH) in Uganda who engage in heavy alcohol use. Methods We analyzed baseline data from the Drinkers Intervention to Prevent Tuberculosis study which enrolls PLWH with latent tuberculosis who engage in heavy alcohol consumption. Using the primary care Post Traumatic Stress Disorder (PTSD) screening scale from the DSM-5 (PC-PTSD-5), probable PTSD was defined as reporting ≥3 of 5 assessed symptoms. We conducted the Alcohol Use Disorders Identification Test-Consumption and assessed demographics, smoking, symptoms of depression, and spirituality/religiosity. Results Of 421 participants enrolled from 2018 through 2020, the majority (68.2%) were male, median age was 40 years (interquartile range [IQR]: 32–47), and median AUDIT-C score was 6 [IQR: 4–8]. Half (50.1%) of the participants reported ever experiencing a traumatic event, and 20.7% reported ≥3 symptoms of PTSD. The most commonly reported PTSD symptoms in the past 1 month in the entire sample were avoidance (28.3%), nightmares (27.3%), and being constantly on guard (21.6%). In multivariable logistic regression analyses, level of alcohol use was not associated with probable PTSD (adjusted odds ratio [AOR] for each AUDIT-C point: (1.02; 95% CI: 0.92–1.14; p = 0.69); however, lifetime smoking (AOR 1.89; 95% CI: 1.10–3.24) and reporting symptoms of depression (AOR 1.89; 95% CI: 1.04–3.44) were independently associated with probable PTSD. Conclusions and recommendations A history of traumatic events and probable PTSD were frequently reported among persons who engage in heavy drinking, living with HIV in Uganda. Level of alcohol use was not associated with probable PTSD in this sample of PLWH with heavy alcohol use, however other behavioral and mental health factors were associated with probable PTSD. These data highlight the high prevalence of PTSD in this group, and the need for screening and interventions for PTSD and mental health problems.

Impact of comorbid post traumatic stress disorder on multiple sclerosis in military veterans: A population-based cohort study

2021 ◽  
pp. 135245852110583
Author(s):  
Mark Leekoff ◽  
William Culpepper ◽  
Shan Jin ◽  
Terry Lee-Wilk ◽  
Mitchell Wallin
Keyword(s):  
Multiple Sclerosis ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Military Veterans ◽  
Brain Mri ◽  
Population Based ◽  
Post Traumatic Stress ◽  
Post Traumatic ◽  
The Impact

Background: Very little is known regarding the impact of post traumatic stress disorder (PTSD) on the course of multiple sclerosis (MS). Objectives: To explore the impact of pre-existing PTSD on MS relapses, magnetic resonance imaging (MRI) activity, and disability in a large population-based cohort. Methods: Military Veterans with MS and PTSD prior to symptom onset (MSPTSD, n = 96) were identified using the Department of Veterans Affairs MS databases. MSPTSD cases were matched to MS controls without PTSD ( n = 95). Number of relapses, number of new T2 lesions and new gadolinium lesions on brain MRI, and neurological disability were abstracted between 2015 and 2019. Results: The mean annualized relapse rate was greater in the MSPTSD group versus controls (0.23 vs 0.06, respectively; p < 0.05), as was the annualized mean number of new T2 and gadolinium-enhancing lesions on brain MRI (0.52 vs 0.16 and 0.29 vs 0.08, respectively; p < 0.05). Disability accrual (time to Disability Status Scale 6.0) was more rapid (23.7 vs 29.5 years, p < 0.05) in relapsing MS patients with PTSD. Conclusion: Patients with MSPTSD have higher disease activity and reach disability endpoints more rapidly than controls. This is the first study to show PTSD as a potentially modifiable risk factor for MS relapses, MRI activity, and disability.

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