scholarly journals How to conduct meta-analysis: a basic tutorial

Author(s):  
Arindam Basu

Meta analysis refers to a process of integration of the results of many studies to arrive at evidence syn- thesis. Meta analysis is similar to systematic review; however, in addition to narrative summary that is conducted in systematic review, in meta analysis, the analysts also numerically pool the results of the studies and arrive at a summary estimate. In this paper, we discuss the key steps of conducting a meta analysis. We will discuss the steps of a simple meta-analysis with a demonstration of the key steps based on a published paper on meta-analysis and systematic review of the effectiveness of salt restricted diet on blood pressure control. This paper is a basic introduction to the process of meta-analysis. In subsequent papers in this series, we will show how you can conduct meta-analysis of diagnostic and screening studies, network meta analyses, and those of diagnostic and screening studies.

Author(s):  
Arindam Basu

Meta analysis refers to a process of integration of the results of many studies to arrive at evidence syn- thesis. Meta analysis is similar to systematic review; however, in addition to narrative summary that is conducted in systematic review, in meta analysis, the analysts also numerically pool the results of the studies and arrive at a summary estimate. In this paper, we discuss the key steps of conducting a meta analysis. We will discuss the steps of a simple meta-analysis with a demonstration of the key steps based on a published paper on meta-analysis and systematic review of the effectiveness of salt restricted diet on blood pressure control. This paper is a basic introduction to the process of meta-analysis. In subsequent papers in this series, we will show how you can conduct meta-analysis of diagnostic and screening studies, network meta analyses, and those of diagnostic and screening studies.


2017 ◽  
Vol 32 (10) ◽  
pp. 1195-1232 ◽  
Author(s):  
Eimear C. Morrissey ◽  
Hannah Durand ◽  
Robby Nieuwlaat ◽  
Tamara Navarro ◽  
R. Brian Haynes ◽  
...  

2021 ◽  
Vol 15 (3) ◽  
Author(s):  
Merve Memisoglu ◽  
Yusuf Çelik

Effective intervention is a significant component in the improvement of blood pressure control and patient adherence. Blood pressure control includes different self-monitoring techniques, mobile health monitoring, or healthcare professionals’ interventions. This study aims to compare, analyze, and interpret the effectiveness of pharmacist-physician collaboration and pharmacist- led interventions. Meta-analysis was performed using MEDLINE via PubMed, EMBASE, EBSCO, Web of Science, Scopus, and the Cochrane Library databases between 2008-2018. Of the 51 relevant systematic reviews identified, 15 were of sufficient quality and included in the data synthesis. The breakdown of the 15 included 7 (n=2026) pharmacist and 8 pharmacist-physician interventions (n=2361). The impact of pharmacist-physician collaboration and pharmacist-led interventions on Systolic Blood Pressure was –8.22 (–11.01; –5.42) (P<0.01) and –7.68 (–9.30; –6.06) (P=0.35), respectively. On the other hand, similar correlation for Diastolic Blood Pressure for the impact of pharmacist-physician collaboration and pharmacist-led interventions was –3.55 (–4.54; –2.55) (P=0.49) and –2.58 (–3.76; –1.39) (P=0.24), respectively. These results suggest that both interventions are effective for blood pressure control. However, when two meta-analyses were compared, it was found that pharmacist-physician collaboration was more effective than pharmacist-led interventions. This finding highlights the importance of multidisciplinary approaches during blood pressure control procedures. When a holistic view is considered; especially cost-effectiveness, future studies must be diversified to encompass a broader context and impact analysis.


2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Arash Mirrahimi ◽  
Erika Reiser ◽  
Laura Chiavaroli ◽  
John L Sievenepiper ◽  
Russell J Souza ◽  
...  

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