scholarly journals Deep-learning convolutional neural networks with transfer learning accurately classify COVID-19 lung infection on portable chest radiographs

PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e10309
Author(s):  
Shreeja Kikkisetti ◽  
Jocelyn Zhu ◽  
Beiyi Shen ◽  
Haifang Li ◽  
Tim Q. Duong

Portable chest X-ray (pCXR) has become an indispensable tool in the management of Coronavirus Disease 2019 (COVID-19) lung infection. This study employed deep-learning convolutional neural networks to classify COVID-19 lung infections on pCXR from normal and related lung infections to potentially enable more timely and accurate diagnosis. This retrospect study employed deep-learning convolutional neural network (CNN) with transfer learning to classify based on pCXRs COVID-19 pneumonia (N = 455) on pCXR from normal (N = 532), bacterial pneumonia (N = 492), and non-COVID viral pneumonia (N = 552). The data was randomly split into 75% training and 25% testing, randomly. A five-fold cross-validation was used for the testing set separately. Performance was evaluated using receiver-operating curve analysis. Comparison was made with CNN operated on the whole pCXR and segmented lungs. CNN accurately classified COVID-19 pCXR from those of normal, bacterial pneumonia, and non-COVID-19 viral pneumonia patients in a multiclass model. The overall sensitivity, specificity, accuracy, and AUC were 0.79, 0.93, and 0.79, 0.85 respectively (whole pCXR), and were 0.91, 0.93, 0.88, and 0.89 (CXR of segmented lung). The performance was generally better using segmented lungs. Heatmaps showed that CNN accurately localized areas of hazy appearance, ground glass opacity and/or consolidation on the pCXR. Deep-learning convolutional neural network with transfer learning accurately classifies COVID-19 on portable chest X-ray against normal, bacterial pneumonia or non-COVID viral pneumonia. This approach has the potential to help radiologists and frontline physicians by providing more timely and accurate diagnosis.

2020 ◽  
Author(s):  
Shreeja Kikkisetti ◽  
Jocelyn Zhu ◽  
Beiyi Shen ◽  
Haifang Li ◽  
Tim Duong

Portable chest x-ray (pCXR) has become an indispensable tool in the management of Coronavirus Disease 2019 (COVID-19) lung infection. This study employed deep-learning convolutional neural networks to classify COVID-19 lung infections on pCXR from normal and related lung infections to potentially enable more timely and accurate diagnosis. This retrospect study employed deep-learning convolutional neural network (CNN) with transfer learning to classify based on pCXRs COVID-19 pneumonia (N=455) on pCXR from normal (N=532), bacterial pneumonia (N=492), and non-COVID viral pneumonia (N=552). The data was split into 75% training and 25% testing. A five-fold cross-validation was used. Performance was evaluated using receiver-operating curve analysis. Comparison was made with CNN operated on the whole pCXR and segmented lungs. CNN accurately classified COVID-19 pCXR from those of normal, bacterial pneumonia, and non-COVID-19 viral pneumonia patients in a multiclass model. The overall sensitivity, specificity, accuracy, and AUC were 0.79, 0.93, and 0.79, 0.85 respectively (whole pCXR), and were 0.91, 0.93, 0.88, and 0.89 (CXR of segmented lung). The performance was generally better using segmented lungs. Heatmaps showed that CNN accurately localized areas of hazy appearance, ground glass opacity and/or consolidation on the pCXR. Deep-learning convolutional neural network with transfer learning accurately classifies COVID-19 on portable chest x-ray against normal, bacterial pneumonia or non-COVID viral pneumonia. This approach has the potential to help radiologists and frontline physicians by providing more timely and accurate diagnosis.


2020 ◽  
Author(s):  
Sarath Pathari ◽  
Rahul U

In this study, a dataset of X-ray images from patients with common viral pneumonia, bacterial pneumonia, confirmed Covid-19 disease was utilized for the automatic detection of the Coronavirus disease. The point of the investigation is to assess the exhibition of cutting edge convolutional neural system structures proposed over the ongoing years for clinical picture order. In particular, the system called Transfer Learning was received. With transfer learning, the location of different variations from the norm in little clinical picture datasets is a reachable objective, regularly yielding amazing outcomes. The datasets used in this trial. Firstly, a collection of 24000 X-ray images includes 6000 images for confirmed Covid-19 disease,6000 confirmed common bacterial pneumonia and 6000 images of normal conditions. The information was gathered and expanded from the accessible X-Ray pictures on open clinical stores. The outcomes recommend that Deep Learning with X-Ray imaging may separate noteworthy biomarkers identified with the Covid-19 sickness, while the best precision, affectability, and particularity acquired is 97.83%, 96.81%, and 98.56% individually.


Author(s):  
Amir Sorayaie Azar ◽  
Ali Ghafari ◽  
Mohammad Ostadi Najar ◽  
Samin Babaei Rikan ◽  
Reza Ghafari ◽  
...  

Purpose: Coronavirus disease 2019 (Covid-19), first reported in December 2019 in Wuhan, China, has become a pandemic. Chest imaging is used for the diagnosis of Covid-19 patients and can address problems concerning Reverse Transcription-Polymerase Chain Reaction (RT-PCR) shortcomings. Chest X-ray images can act as an appropriate alternative to Computed Tomography (CT) for diagnosing Covid-19. The purpose of this study is to use a Deep Learning method for diagnosing Covid-19 cases using chest X-ray images. Thus, we propose Covidense based on the pre-trained Densenet-201 model and is trained on a dataset comprising chest X-ray images of Covid-19, normal, bacterial pneumonia, and viral pneumonia cases. Materials and Methods: In this study, a total number of 1280 chest X-ray images of Covid-19, normal, bacterial and viral pneumonia cases were collected from open access repositories. Covidense, a convolutional neural network model, is based on the pre-trained DenseNet-201 architecture, and after pre-processing the images, it has been trained and tested on the images using the 5-fold cross-validation method. Results: The accuracy of different classifications including classification of two classes (Covid-19, normal), three classes 1 (Covid-19, normal and bacterial pneumonia), three classes 2 (Covid-19, normal and viral pneumonia), and four classes (Covid-19, normal, bacterial pneumonia and viral pneumonia) are 99.46%, 92.86%, 93.91 %, and 91.01% respectively. Conclusion: This model can differentiate pneumonia caused by Covid-19 from other types of pneumonia, including bacterial and viral. The proposed model offers high accuracy and can be of great help for effective screening. Thus, reducing the rate of infection spread. Also, it can act as a complementary tool for the detection and diagnosis of Covid-19.


2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Lal Hussain ◽  
Tony Nguyen ◽  
Haifang Li ◽  
Adeel A. Abbasi ◽  
Kashif J. Lone ◽  
...  

Abstract Background The large volume and suboptimal image quality of portable chest X-rays (CXRs) as a result of the COVID-19 pandemic could post significant challenges for radiologists and frontline physicians. Deep-learning artificial intelligent (AI) methods have the potential to help improve diagnostic efficiency and accuracy for reading portable CXRs. Purpose The study aimed at developing an AI imaging analysis tool to classify COVID-19 lung infection based on portable CXRs. Materials and methods Public datasets of COVID-19 (N = 130), bacterial pneumonia (N = 145), non-COVID-19 viral pneumonia (N = 145), and normal (N = 138) CXRs were analyzed. Texture and morphological features were extracted. Five supervised machine-learning AI algorithms were used to classify COVID-19 from other conditions. Two-class and multi-class classification were performed. Statistical analysis was done using unpaired two-tailed t tests with unequal variance between groups. Performance of classification models used the receiver-operating characteristic (ROC) curve analysis. Results For the two-class classification, the accuracy, sensitivity and specificity were, respectively, 100%, 100%, and 100% for COVID-19 vs normal; 96.34%, 95.35% and 97.44% for COVID-19 vs bacterial pneumonia; and 97.56%, 97.44% and 97.67% for COVID-19 vs non-COVID-19 viral pneumonia. For the multi-class classification, the combined accuracy and AUC were 79.52% and 0.87, respectively. Conclusion AI classification of texture and morphological features of portable CXRs accurately distinguishes COVID-19 lung infection in patients in multi-class datasets. Deep-learning methods have the potential to improve diagnostic efficiency and accuracy for portable CXRs.


Measurement ◽  
2021 ◽  
pp. 109953
Author(s):  
Adhiyaman Manickam ◽  
Jianmin Jiang ◽  
Yu Zhou ◽  
Abhinav Sagar ◽  
Rajkumar Soundrapandiyan ◽  
...  

2020 ◽  
Vol 10 (4) ◽  
pp. 213 ◽  
Author(s):  
Ki-Sun Lee ◽  
Jae Young Kim ◽  
Eun-tae Jeon ◽  
Won Suk Choi ◽  
Nan Hee Kim ◽  
...  

According to recent studies, patients with COVID-19 have different feature characteristics on chest X-ray (CXR) than those with other lung diseases. This study aimed at evaluating the layer depths and degree of fine-tuning on transfer learning with a deep convolutional neural network (CNN)-based COVID-19 screening in CXR to identify efficient transfer learning strategies. The CXR images used in this study were collected from publicly available repositories, and the collected images were classified into three classes: COVID-19, pneumonia, and normal. To evaluate the effect of layer depths of the same CNN architecture, CNNs called VGG-16 and VGG-19 were used as backbone networks. Then, each backbone network was trained with different degrees of fine-tuning and comparatively evaluated. The experimental results showed the highest AUC value to be 0.950 concerning COVID-19 classification in the experimental group of a fine-tuned with only 2/5 blocks of the VGG16 backbone network. In conclusion, in the classification of medical images with a limited number of data, a deeper layer depth may not guarantee better results. In addition, even if the same pre-trained CNN architecture is used, an appropriate degree of fine-tuning can help to build an efficient deep learning model.


2021 ◽  
Author(s):  
Aya Elagili Elagili ◽  
Ibrahim Ighneiwa Ighneiwa ◽  
Zakariya Rajab Rajab

Author(s):  
Arshia Rehman ◽  
Saeeda Naz ◽  
Ahmed Khan ◽  
Ahmad Zaib ◽  
Imran Razzak

AbstractBackgroundCoronavirus disease (COVID-19) is an infectious disease caused by a new virus. Exponential growth is not only threatening lives, but also impacting businesses and disrupting travel around the world.AimThe aim of this work is to develop an efficient diagnosis of COVID-19 disease by differentiating it from viral pneumonia, bacterial pneumonia and healthy cases using deep learning techniques.MethodIn this work, we have used pre-trained knowledge to improve the diagnostic performance using transfer learning techniques and compared the performance different CNN architectures.ResultsEvaluation results using K-fold (10) showed that we have achieved state of the art performance with overall accuracy of 98.75% on the perspective of CT and X-ray cases as a whole.ConclusionQuantitative evaluation showed high accuracy for automatic diagnosis of COVID-19. Pre-trained deep learning models develop in this study could be used early screening of coronavirus, however it calls for extensive need to CT or X-rays dataset to develop a reliable application.


2020 ◽  
Author(s):  
Ebru Erdem ◽  
Tolga Aydın

Abstract COVID-19 is an important threat worldwide. This disease is caused by the novel SARS-CoV-2. CXR and CT images reveal specific information about the disease. However, when interpreting these images, experiencing an overlap with other lung infections complicates the detection of the disease. Due to this situation, the need for computer-aided systems is increasing day by day. In this study, solutions were developed with proposed models based on deep neural networks (DNN). All the analyses were performed on a publicly available CXR dataset. This study offers a comparison of the deep learning models (SqueezeNet, Inception-V3, VGG16, MobileNet, Xception, VGG19+MobileNet (Concatenated)) that results in the detection and classification of a disease. Empirical evaluation demonstrates that the Inception-V3 model gives 90% accuracy with 100% precision for the COVID-19 infection. This model has been provided with better results compared to other models. In addition to the studies in the literature, it has been observed that the proposed pre-trained-based concatenated model gives very similar successful results to the other models.


Sign in / Sign up

Export Citation Format

Share Document