scholarly journals Covidense: Providing a Suitable Solution for Diagnosing Covid-19 Lung Infection Based on Deep Learning from Chest X-Ray Images of Patients

2021 ◽  
Author(s):  
Amir Sorayaie Azar ◽  
Ali Ghafari ◽  
Mohammad Ostadi Najar ◽  
Samin Babaei Rikan ◽  
Reza Ghafari ◽  
...  
Keyword(s):  
Deep Learning ◽  
Bacterial Pneumonia ◽  
Viral Pneumonia ◽  
X Ray ◽  
Proposed Model ◽  
Chest X Ray ◽  
Polymerase Chain ◽  
Detection And Diagnosis ◽  
Fold Cross Validation

Purpose: Coronavirus disease 2019 (Covid-19), first reported in December 2019 in Wuhan, China, has become a pandemic. Chest imaging is used for the diagnosis of Covid-19 patients and can address problems concerning Reverse Transcription-Polymerase Chain Reaction (RT-PCR) shortcomings. Chest X-ray images can act as an appropriate alternative to Computed Tomography (CT) for diagnosing Covid-19. The purpose of this study is to use a Deep Learning method for diagnosing Covid-19 cases using chest X-ray images. Thus, we propose Covidense based on the pre-trained Densenet-201 model and is trained on a dataset comprising chest X-ray images of Covid-19, normal, bacterial pneumonia, and viral pneumonia cases. Materials and Methods: In this study, a total number of 1280 chest X-ray images of Covid-19, normal, bacterial and viral pneumonia cases were collected from open access repositories. Covidense, a convolutional neural network model, is based on the pre-trained DenseNet-201 architecture, and after pre-processing the images, it has been trained and tested on the images using the 5-fold cross-validation method. Results: The accuracy of different classifications including classification of two classes (Covid-19, normal), three classes 1 (Covid-19, normal and bacterial pneumonia), three classes 2 (Covid-19, normal and viral pneumonia), and four classes (Covid-19, normal, bacterial pneumonia and viral pneumonia) are 99.46%, 92.86%, 93.91 %, and 91.01% respectively. Conclusion: This model can differentiate pneumonia caused by Covid-19 from other types of pneumonia, including bacterial and viral. The proposed model offers high accuracy and can be of great help for effective screening. Thus, reducing the rate of infection spread. Also, it can act as a complementary tool for the detection and diagnosis of Covid-19.

scholarly journals Deep-learning convolutional neural networks with transfer learning accurately classify COVID-19 lung infection on portable chest radiographs

PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e10309
Author(s):  
Shreeja Kikkisetti ◽  
Jocelyn Zhu ◽  
Beiyi Shen ◽  
Haifang Li ◽  
Tim Q. Duong
Keyword(s):  
Deep Learning ◽  
Transfer Learning ◽  
Bacterial Pneumonia ◽  
Lung Infection ◽  
Accurate Diagnosis ◽  
Viral Pneumonia ◽  
X Ray ◽  
Portable Chest ◽  
Chest X Ray ◽  
Lung Infections

Portable chest X-ray (pCXR) has become an indispensable tool in the management of Coronavirus Disease 2019 (COVID-19) lung infection. This study employed deep-learning convolutional neural networks to classify COVID-19 lung infections on pCXR from normal and related lung infections to potentially enable more timely and accurate diagnosis. This retrospect study employed deep-learning convolutional neural network (CNN) with transfer learning to classify based on pCXRs COVID-19 pneumonia (N = 455) on pCXR from normal (N = 532), bacterial pneumonia (N = 492), and non-COVID viral pneumonia (N = 552). The data was randomly split into 75% training and 25% testing, randomly. A five-fold cross-validation was used for the testing set separately. Performance was evaluated using receiver-operating curve analysis. Comparison was made with CNN operated on the whole pCXR and segmented lungs. CNN accurately classified COVID-19 pCXR from those of normal, bacterial pneumonia, and non-COVID-19 viral pneumonia patients in a multiclass model. The overall sensitivity, specificity, accuracy, and AUC were 0.79, 0.93, and 0.79, 0.85 respectively (whole pCXR), and were 0.91, 0.93, 0.88, and 0.89 (CXR of segmented lung). The performance was generally better using segmented lungs. Heatmaps showed that CNN accurately localized areas of hazy appearance, ground glass opacity and/or consolidation on the pCXR. Deep-learning convolutional neural network with transfer learning accurately classifies COVID-19 on portable chest X-ray against normal, bacterial pneumonia or non-COVID viral pneumonia. This approach has the potential to help radiologists and frontline physicians by providing more timely and accurate diagnosis.

scholarly journals Metaheuristic-based Deep COVID-19 Screening Model from Chest X-Ray Images

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Manjit Kaur ◽  
Vijay Kumar ◽  
Vaishali Yadav ◽  
Dilbag Singh ◽  
Naresh Kumar ◽  
...  
Keyword(s):  
Deep Learning ◽  
Learning Models ◽  
Huge Number ◽  
X Ray ◽  
Screening Model ◽  
Proposed Model ◽  
Strength Pareto Evolutionary Algorithm ◽  
Chest X Ray ◽  
Deep Learning Model

COVID-19 has affected the whole world drastically. A huge number of people have lost their lives due to this pandemic. Early detection of COVID-19 infection is helpful for treatment and quarantine. Therefore, many researchers have designed a deep learning model for the early diagnosis of COVID-19-infected patients. However, deep learning models suffer from overfitting and hyperparameter-tuning issues. To overcome these issues, in this paper, a metaheuristic-based deep COVID-19 screening model is proposed for X-ray images. The modified AlexNet architecture is used for feature extraction and classification of the input images. Strength Pareto evolutionary algorithm-II (SPEA-II) is used to tune the hyperparameters of modified AlexNet. The proposed model is tested on a four-class (i.e., COVID-19, tuberculosis, pneumonia, or healthy) dataset. Finally, the comparisons are drawn among the existing and the proposed models.

scholarly journals Classification of x-ray images for detection of childhood pneumonia using pre-trained neural networks

2020 ◽  
Vol 12 (3) ◽  
pp. 132-141
Author(s):  
Nator Junior Carvalho da Costa ◽  
Jose Vigno Moura Sousa ◽  
Domingos Bruno Sousa Santos ◽  
Francisco das Chagas Fontenele Marques Junior ◽  
Rodrigo Teixeira de Melo
Keyword(s):  
Neural Networks ◽  
Bacterial Pneumonia ◽  
Good Accuracy ◽  
Viral Pneumonia ◽  
Data Set ◽  
X Ray ◽  
Chest X Ray ◽  
And Training ◽  
Validation Testing

This paper describes a comparison between three pre-trained neural networks for the classification of chest X-ray images: Xception, Inception V3, and NasNetLarge. Networks were implemented using learning transfer; The database used was the chest x-ray data set, which contains a total of 5856 chest x-ray images of pediatric patients aged one to five years, with three classes: Normal Viral Pneumonia and Bacterial Pneumonia. Data were divided into three groups: validation, testing and training. A comparison was made with the work of kermany who implemented the Inception V3 network in two ways: (Pneumonia X Normal) and (Bacterial Pneumonia X Viral Pneumonia). The nets used had good accuracy, being the NasNetLarge network the best precision, which was 95.35 \% (Pneumonia X Normal) and 91.79 \% (Viral Pneumonia X Bacterial Pneumonia) against 92.80 \% in (Pneumonia X Normal) and 90.70 \% (Viral Pneumonia X Bacterial Pneumonia) from kermany's work, the Xception network also achieved an improvement in accuracy compared to kermany's work, with 93.59 \% at (Normal X Pneumonia) and 91.03 \% in (Viral Pneumonia X Bacterial Pneumonia).

scholarly journals Deep-learning convolutional neural networks with transfer learning accurately classify COVID19 lung infection on portable chest radiographs

2020 ◽  
Author(s):  
Shreeja Kikkisetti ◽  
Jocelyn Zhu ◽  
Beiyi Shen ◽  
Haifang Li ◽  
Tim Duong
Keyword(s):  
Deep Learning ◽  
Transfer Learning ◽  
Bacterial Pneumonia ◽  
Lung Infection ◽  
Accurate Diagnosis ◽  
Viral Pneumonia ◽  
X Ray ◽  
Portable Chest ◽  
Chest X Ray ◽  
Lung Infections

Portable chest x-ray (pCXR) has become an indispensable tool in the management of Coronavirus Disease 2019 (COVID-19) lung infection. This study employed deep-learning convolutional neural networks to classify COVID-19 lung infections on pCXR from normal and related lung infections to potentially enable more timely and accurate diagnosis. This retrospect study employed deep-learning convolutional neural network (CNN) with transfer learning to classify based on pCXRs COVID-19 pneumonia (N=455) on pCXR from normal (N=532), bacterial pneumonia (N=492), and non-COVID viral pneumonia (N=552). The data was split into 75% training and 25% testing. A five-fold cross-validation was used. Performance was evaluated using receiver-operating curve analysis. Comparison was made with CNN operated on the whole pCXR and segmented lungs. CNN accurately classified COVID-19 pCXR from those of normal, bacterial pneumonia, and non-COVID-19 viral pneumonia patients in a multiclass model. The overall sensitivity, specificity, accuracy, and AUC were 0.79, 0.93, and 0.79, 0.85 respectively (whole pCXR), and were 0.91, 0.93, 0.88, and 0.89 (CXR of segmented lung). The performance was generally better using segmented lungs. Heatmaps showed that CNN accurately localized areas of hazy appearance, ground glass opacity and/or consolidation on the pCXR. Deep-learning convolutional neural network with transfer learning accurately classifies COVID-19 on portable chest x-ray against normal, bacterial pneumonia or non-COVID viral pneumonia. This approach has the potential to help radiologists and frontline physicians by providing more timely and accurate diagnosis.

scholarly journals Transfer Learning Based Multiclass Classification For Covid-19 Detection Using Chest X-Rays

2021 ◽  
Author(s):  
Japman Singh Monga ◽  
Yuvraj Singh Champawat ◽  
Seema Kharb
Keyword(s):  
Deep Learning ◽  
Transfer Learning ◽  
X Rays ◽  
Performance Parameters ◽  
Chain Reaction ◽  
X Ray ◽  
Proposed Model ◽  
Chest X Ray ◽  
Polymerase Chain ◽  
Deep Learning Model

Abstract In the year 2020 world came to a halt due to spread of Covid-19 or SARS-CoV2 which was first identified in Wuhan, China. Since then, it has caused plethora of problems around the globe such as loss of millions of lives, economic instability etc. Less effectiveness of detection through Reverse Transcription Polymerase Chain Reaction and also prolonged time needed for detection through the same calls for a substitute for Covid-19 detection. Hence, in this study, we aim to develop a transfer learning based multi-class classifier using Chest X-Ray images which will classify the X-Ray images in 3 classes (Covid-19, Pneumonia, Normal). Further, the proposed model has been trained with deep learning classifiers namely: DenseNet201, Xception, ResNet50V2, VGG16, VGG-19, InceptionResNetV2 .These are evaluated on the basis of accuracy, precision and recall as performance parameters. It has been observed that DenseNet201 is the best deep learning model with 82.2% accuracy.

scholarly journals Transfer Learning Based Multiclass Classification For Covid-19 Detection Using Chest X-Rays

2021 ◽  
Author(s):  
Japman Singh Monga ◽  
Yuvraj Singh Champawat ◽  
Seema Kharb
Keyword(s):  
Deep Learning ◽  
Transfer Learning ◽  
X Rays ◽  
Performance Parameters ◽  
Chain Reaction ◽  
X Ray ◽  
Proposed Model ◽  
Chest X Ray ◽  
Polymerase Chain ◽  
Deep Learning Model

Abstract In the year 2020 world came to a halt due to spread of Covid-19 or SARS-CoV2 which was first identified in Wuhan, China. Since then, it has caused plethora of problems around the globe such as loss of millions of lives, economic instability etc. Less effectiveness of detection through Reverse Transcription Polymerase Chain Reaction and also prolonged time needed for detection through the same calls for a substitute for Covid-19 detection. Hence, in this study, we aim to develop a transfer learning based multi-class classifier using Chest X-Ray images which will classify the X-Ray images in 3 classes (Covid-19, Pneumonia, Normal). Further, the proposed model has been trained with deep learning classifiers namely: DenseNet201, Xception, ResNet50V2, VGG16, VGG-19, InceptionResNetV2 .These are evaluated on the basis of accuracy, precision and recall as performance parameters. It has been observed that DenseNet201 is the best deep learning model with 82.2% accuracy.

scholarly journals Chest X-Ray Classification of Lung Diseases Using Deep Learning

2021 ◽  
Vol 1 (1) ◽  
pp. 12-18
Author(s):  
Yew Fai Cheah
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Lung Disease ◽  
Lung Diseases ◽  
Viral Pneumonia ◽  
Normal Lung ◽  
X Ray ◽  
Chest X Ray ◽  
Online Sources

Chest X-ray images can be used to detect lung diseases such as COVID-19, viral pneumonia, and tuberculosis (TB). These diseases have similar patterns and diagnoses, making it difficult for clinicians and radiologists to differentiate between them. This paper uses convolutional neural networks (CNNs) to diagnose lung disease using chest X-ray images obtained from online sources. The classification task is separated into three and four classes, with COVID-19, normal, TB, and viral pneumonia, while the three-class problem excludes the normal lung. During testing, AlexNet and ResNet-18 gave promising results, scoring more than 95% accuracy.

scholarly journals Machine learning applied on chest x-ray can aid in the diagnosis of COVID-19: a first experience from Lombardy, Italy

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Isabella Castiglioni ◽  
Davide Ippolito ◽  
Matteo Interlenghi ◽  
Caterina Beatrice Monti ◽  
Christian Salvatore ◽  
...  
Keyword(s):  
Deep Learning ◽  
Area Under The Curve ◽  
Clinical Information ◽  
Training Dataset ◽  
Independent Dataset ◽  
X Ray ◽  
Learning Classifier ◽  
Chest X Ray ◽  
Polymerase Chain ◽  
Deep Learning Model

Abstract Background We aimed to train and test a deep learning classifier to support the diagnosis of coronavirus disease 2019 (COVID-19) using chest x-ray (CXR) on a cohort of subjects from two hospitals in Lombardy, Italy. Methods We used for training and validation an ensemble of ten convolutional neural networks (CNNs) with mainly bedside CXRs of 250 COVID-19 and 250 non-COVID-19 subjects from two hospitals (Centres 1 and 2). We then tested such system on bedside CXRs of an independent group of 110 patients (74 COVID-19, 36 non-COVID-19) from one of the two hospitals. A retrospective reading was performed by two radiologists in the absence of any clinical information, with the aim to differentiate COVID-19 from non-COVID-19 patients. Real-time polymerase chain reaction served as the reference standard. Results At 10-fold cross-validation, our deep learning model classified COVID-19 and non-COVID-19 patients with 0.78 sensitivity (95% confidence interval [CI] 0.74–0.81), 0.82 specificity (95% CI 0.78–0.85), and 0.89 area under the curve (AUC) (95% CI 0.86–0.91). For the independent dataset, deep learning showed 0.80 sensitivity (95% CI 0.72–0.86) (59/74), 0.81 specificity (29/36) (95% CI 0.73–0.87), and 0.81 AUC (95% CI 0.73–0.87). Radiologists’ reading obtained 0.63 sensitivity (95% CI 0.52–0.74) and 0.78 specificity (95% CI 0.61–0.90) in Centre 1 and 0.64 sensitivity (95% CI 0.52–0.74) and 0.86 specificity (95% CI 0.71–0.95) in Centre 2. Conclusions This preliminary experience based on ten CNNs trained on a limited training dataset shows an interesting potential of deep learning for COVID-19 diagnosis. Such tool is in training with new CXRs to further increase its performance.

scholarly journals Deep Learning Classification of Chest X-Ray Images

2020 ◽  
Author(s):  
Mohammad S. Majdi ◽  
Khalil N. Salman ◽  
Michael F. Morris ◽  
Nirav C. Merchant ◽  
Jeffrey J. Rodriguez
Keyword(s):  
Deep Learning ◽  
X Ray ◽  
Chest X Ray

scholarly journals Unveiling COVID-19 from CHEST X-Ray with Deep Learning: A Hurdles Race with Small Data

2020 ◽  
Vol 17 (18) ◽  
pp. 6933 ◽  
Author(s):  
Enzo Tartaglione ◽  
Carlo Alberto Barbano ◽  
Claudio Berzovini ◽  
Marco Calandri ◽  
Marco Grangetto
Keyword(s):  
Deep Learning ◽  
Scientific Community ◽  
Northern Italy ◽  
Medium Size ◽  
Small Data ◽  
Early Screening ◽  
X Ray ◽  
Chest X Ray ◽  
Statistical Results

The possibility to use widespread and simple chest X-ray (CXR) imaging for early screening of COVID-19 patients is attracting much interest from both the clinical and the AI community. In this study we provide insights and also raise warnings on what is reasonable to expect by applying deep learning to COVID classification of CXR images. We provide a methodological guide and critical reading of an extensive set of statistical results that can be obtained using currently available datasets. In particular, we take the challenge posed by current small size COVID data and show how significant can be the bias introduced by transfer-learning using larger public non-COVID CXR datasets. We also contribute by providing results on a medium size COVID CXR dataset, just collected by one of the major emergency hospitals in Northern Italy during the peak of the COVID pandemic. These novel data allow us to contribute to validate the generalization capacity of preliminary results circulating in the scientific community. Our conclusions shed some light into the possibility to effectively discriminate COVID using CXR.

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