Alteration of Serum 25(OH) Vitamin D, Vitamin D Binding Protein, and C-reactive Protein Levels in Acute Leukemia Patients

2018 ◽  
Vol 64 (09/2018) ◽  
Author(s):  
Liejun Jiang ◽  
Xiaomei Zhang ◽  
Yanyun Chen ◽  
Xiaocong Huo ◽  
Shuang Deng ◽  
...  
Keyword(s):  
Vitamin D ◽  
Acute Leukemia ◽  
Binding Protein ◽  
Vitamin D Binding Protein ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
25 Oh Vitamin D

scholarly journals Impact of Etanercept on Vitamin D Status and Vitamin D-binding Protein in Bio-naïve Patients with Psoriasis

2021 ◽  
Author(s):  
Maria Siekkeri Vandikas ◽  
Kerstin Landin-Wilhelmsen ◽  
Sam Polesie ◽  
Martin Gillstedt ◽  
Amra Osmancevic
Keyword(s):  
Vitamin D ◽  
Binding Protein ◽  
Vitamin D Metabolites ◽  
Vitamin D Status ◽  
Vitamin D Binding Protein ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Highly Sensitive ◽  
Baseline Levels ◽  
The Impact

High levels of serum vitamin D-binding protein have been shown previously in patients with psoriasis compared with healthy controls; a possible role in inflammation is implied. The primary objective of this study was to investigate the impact of 24-week etanercept treatment on vitamin D status and vitamin D-binding protein in patients with psoriasis. The secondary aim was to explore whether pre-treatment vitamin D levels could predict the treatment effect. A prospective observational study was performed, including 20 patients with psoriasis and 15 controls. Serum samples i.a. were analysed for vitamin D metabolites, vitamin D-binding protein and highly sensitive C-reactive protein. Baseline levels of vitamin D-binding protein were higher in patients with self-reported arthropathy than in those without. After 24 weeks’ treatment, an improvement in psoriasis was noted, as was a decrease in highly sensitive C-reactive protein. Vitamin D-binding protein decreased in those with self-reported arthropathy. Higher baseline levels of vitamin D were associated with partly faster and greater improvement in psoriasis. Vitamin D-binding protein may have an inflammatory biomarker role.

scholarly journals Serum vitamin D and vitamin-D-binding protein levels in children with chronic hepatitis B

2021 ◽  
Vol 27 (3) ◽  
pp. 255-266
Author(s):  
Cai-Zhi Huang ◽  
Jie Zhang ◽  
Lin Zhang ◽  
Cui-Hua Yu ◽  
Yi Mo ◽  
...  
Keyword(s):  
Vitamin D ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Binding Protein ◽  
Serum Vitamin ◽  
Vitamin D Binding Protein ◽  
Serum Vitamin D ◽  
Protein Levels

Transcortin and vitamin D-binding protein levels in mouse serum

1986 ◽  
Vol 109 (2) ◽  
pp. 141-147 ◽  
Author(s):  
D. Faict ◽  
P. De Moor ◽  
R. Bouillon ◽  
W. Heyns ◽  
H.-J. Heiniger ◽  
...  
Keyword(s):  
Vitamin D ◽  
Sex Difference ◽  
Binding Protein ◽  
Strain Difference ◽  
Mouse Strains ◽  
Mouse Serum ◽  
Adult Males ◽  
Vitamin D Binding Protein ◽  
Protein Levels ◽  
The Mean

ABSTRACT The influence of age, sex and strain on the serum concentration of transcortin (corticosteroid-binding globulin) and vitamin D-binding protein (DBP) in mice was investigated. The effect of age was studied in two strains, C57BL/6JPfd and BALB/cmHeAPfd. The concentration of transcortin and DBP increased with age. In young animals the concentration of each protein showed a significant strain difference, which disappeared in older mice for DBP, but not for transcortin. In 7-day-old animals, no sex difference was observed for either protein, but in older animals a clear sex difference was found for transcortin. Adult males tended to have somewhat higher levels of DBP than adult females, but this difference was significant only on day 70. The variation in transcortin and DBP levels was further investigated in a large number of mouse strains. The DBP concentration did not markedly vary among strains (5·98–9·65 μmol/l in males and 5·08–8·85 μmol/l in females). Transcortin, however, showed marked strain variations, ranging from 0·72 to 2·06 μmol/l in males and from 1·02 to 4·55 μmol/l in females and there was a significant correlation (r= 0·66, n= 26, P<0·001) between the mean transcortin levels in males and females of different strains. Interstrain variation was much higher than intrastrain variation or variation among related strains, suggesting that the transcortin concentration is largely controlled by genetically determined factors. There was a significant correlation (r= 0·82, n = 9, P<0·01) between the mean corticosterone and transcortin concentrations (measured at 21.00 h). Consequently, differences in the free corticosterone levels in the serum of various mouse strains were smaller than the differences in the total corticosterone concentrations. The affinity of transcortin for corticosterone was similar in all but one strain; however, transcortin of the RIIIS/J strain showed a lower affinity for corticosterone. J. Endocr. (1986) 109, 141–147

scholarly journals Prevalence of vitamin D deficiency in women from southern Brazil and association with vitamin D-binding protein levels and GC-DBP gene polymorphisms

PLoS ONE ◽  
2019 ◽  
Vol 14 (12) ◽  
pp. e0226215
Author(s):  
Betânia Rodrigues Santos ◽  
Nathália Cruz Costa ◽  
Thais Rasia Silva ◽  
Karen Oppermann ◽  
Jose Antonio Magalhães ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Gene Polymorphisms ◽  
Binding Protein ◽  
Southern Brazil ◽  
Vitamin D Binding Protein ◽  
Protein Levels

Serum 25-hydroxyvitamin D and vitamin D-binding protein levels and mineral metabolism after partial and total gastrectomy

1980 ◽  
Vol 79 (2) ◽  
pp. 255-258 ◽  
Author(s):  
Michio Imawari ◽  
Kunihisa Kozawa ◽  
Yasuo Akanuma ◽  
Sumihiko Koizumi ◽  
Hiroshige Itakura ◽  
...  
Keyword(s):  
Vitamin D ◽  
Total Gastrectomy ◽  
Mineral Metabolism ◽  
Binding Protein ◽  
Vitamin D Binding Protein ◽  
Hydroxyvitamin D ◽  
Protein Levels ◽  
25 Hydroxyvitamin D

Diminished serum Gc (vitamin D-binding protein) levels and increased Gc:G-actin complexes in a hamster model of fulminant hepatic necrosis

Hepatology ◽  
1987 ◽  
Vol 7 (5) ◽  
pp. 825-830 ◽  
Author(s):  
William M. Lee ◽  
David L. Emerson ◽  
William O. Young ◽  
Pascal J. Goldschmidt-Clermont ◽  
David J. Jollow ◽  
...  
Keyword(s):  
Vitamin D ◽  
Binding Protein ◽  
Hepatic Necrosis ◽  
Vitamin D Binding Protein ◽  
Hamster Model ◽  
Protein Levels
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