Necrotizing Fasciitis of the Breast Requiring a Life-Saving Mastectomy: A Case Report and Literature Review

Abstract Background: Marfan syndrome (MFS) is a connective tissue disorder that can lead to aortic disease, arrhythmias and heart failure. Many centers are reluctant to offer orthotopic heart transplantation (OHT) for patients with MFS with concurrent aortic disease due to complexity of the surgery and perceived inferior results when compared to patients without MFS. Methods: We present a case of a patient with MFS with previous Bentall procedure who underwent successful OHT, accompanied by a literature review on OHT performed for patients with MFS. Results and Conclusions: Patients with MFS who underwent OHT had no difference in mortality compared to patients without MFS. Even though OHT is technically more challenging when combined with concurrent intervention for aortic disease, it should be considered as a life-saving operation for patients with MFS.

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Osteomyelitis Infection ofMycobacterium marinum: A Case Report and Literature Review

Case Reports in Infectious Diseases ◽

10.1155/2015/905920 ◽

2015 ◽

Vol 2015 ◽

pp. 1-5 ◽

Cited By ~ 8

Author(s):

Hao H. Nguyen ◽

Nada Fadul ◽

Muhammad S. Ashraf ◽

Dawd S. Siraj

Keyword(s):

Case Report ◽

Soft Tissue ◽

Literature Review ◽

Necrotizing Fasciitis ◽

Soft Tissue Infection ◽

Immunocompromised Patient ◽

Skin Lesions ◽

Immunocompromised Patients ◽

Deep Soft Tissue ◽

Invasive Infections

Mycobacterium marinum(M. marinum) is a ubiquitous waterborne organism that grows optimally at temperatures around 30°C. It is a nontuberculousMycobacteriumfound in nonchlorinated water with worldwide prevalence. It is the most common atypicalMycobacteriumthat causes opportunistic infection in humans.M. marinumcan cause superficial infections and localized invasive infections in humans, with the hands being the sites most frequently affected. It can cause skin lesions, which are either single, papulonodular lesions, confined to an extremity, or may resemble cutaneous sporotrichosis. This infection can also cause deeper infections including tenosynovitis, bursitis, arthritis, and osteomyelitis. Disseminated infections and visceral involvements have been reported in immunocompromised patients. We here report a case of severe deep soft tissue infection with necrotizing fasciitis and osteomyelitis of the left upper extremity (LUE) caused byM. marinumin an immunocompromised patient.

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Limb Salvage in a Diabetic with Necrotizing Fasciitis: Case Report and Literature Review

Foot & Ankle ◽

10.1177/107110078600600405 ◽

1986 ◽

Vol 6 (4) ◽

pp. 199-207

Author(s):

Steven B. Carlow ◽

Richard L. Jacobs ◽

Danica K. Vedder

Keyword(s):

Case Report ◽

Soft Tissue ◽

Early Diagnosis ◽

Literature Review ◽

Necrotizing Fasciitis ◽

Limb Salvage ◽

Clinical Signs ◽

Tissue Biopsy ◽

Functional Limb

Necrotizing fasciitis must be considered in a diabetic with cutaneous ulceration. A case report of limb salvage in a 48-year-old diabetic female with progressive necrotizing fasciitis is presented. Methods of early diagnosis including clinical signs, radiographs, and soft tissue biopsy of the involved extremity are reviewed. The microbiology of the disease is also discussed. A modification of the Orr technique using infrequent dressing changes in the management of necrotizing fasciitis is presented. In our case this resulted in preservation of life and a functional limb.

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