scholarly journals The Synergistic Effects of Agarose Scaffold Supplemented with Low-molecular-weight Silk Fibroin in Bone Tissue Regeneration

2011 ◽  
Vol 23 (2) ◽  
pp. 193-199 ◽  
Author(s):  
Seung-Won Park ◽  
Tae-Won Goo ◽  
Seong-Ryul Kim ◽  
Hae-Yong Kweon ◽  
Seok-Woo Kang
Keyword(s):  
Molecular Weight ◽  
Bone Tissue ◽  
Silk Fibroin ◽  
Tissue Regeneration ◽  
Synergistic Effects ◽  
Bone Tissue Regeneration ◽  
Low Molecular Weight

Biocompatibility of plasma-treated poly(3-hydroxybutyrate-co-3-hydroxyvalerate) nanofiber mats modified by silk fibroin for bone tissue regeneration

2016 ◽  
Vol 68 ◽  
pp. 842-850 ◽  
Author(s):  
Irem Unalan ◽  
Oylum Colpankan ◽  
Aylin Ziylan Albayrak ◽  
Cansu Gorgun ◽  
Aylin Sendemir Urkmez
Keyword(s):  
Bone Tissue ◽  
Silk Fibroin ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
Nanofiber Mats

Silk fibroin membrane used for guided bone tissue regeneration

2017 ◽  
Vol 70 ◽  
pp. 148-154 ◽  
Author(s):  
Yurong Cai ◽  
Junmao Guo ◽  
Cen Chen ◽  
Chenxue Yao ◽  
Sung-Min Chung ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Silk Fibroin ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration

scholarly journals Production of Composite Scaffold Containing Silk Fibroin, Chitosan, and Gelatin for 3D Cell Culture and Bone Tissue Regeneration

2017 ◽  
Vol 23 ◽  
pp. 5311-5320 ◽  
Author(s):  
Jianqing Li ◽  
Qiuke Wang ◽  
Yebo Gu ◽  
Yu Zhu ◽  
Liang Chen ◽  
...  
Keyword(s):  
Cell Culture ◽  
Bone Tissue ◽  
Silk Fibroin ◽  
Tissue Regeneration ◽  
Composite Scaffold ◽  
3D Cell Culture ◽  
Bone Tissue Regeneration

Fabrication of Hydroxyapatite-Chitosan-Silk Fibroin Based Composite Film as Bone Tissue Regeneration Material

2020 ◽  
pp. 437-445
Author(s):  
Sharda Gupta ◽  
Rupsha Mukherjee ◽  
Rajendra Kumar Jangle ◽  
Deependra Singh ◽  
Manju Singh ◽  
...  
Keyword(s):  
Composite Film ◽  
Bone Tissue ◽  
Silk Fibroin ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration

scholarly journals Zn-substituted Mg2SiO4 nanoparticles-incorporated PCL-silk fibroin composite scaffold: A multifunctional platform towards bone tissue regeneration

2021 ◽  
pp. 112242
Author(s):  
Ashkan Bigham ◽  
Amin Orash Mahmoud Salehi ◽  
Mohammad Rafienia ◽  
Mohammad Reza Salamat ◽  
Shahram Rahmati ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Silk Fibroin ◽  
Tissue Regeneration ◽  
Composite Scaffold ◽  
Bone Tissue Regeneration ◽  
Multifunctional Platform

Biocomposite scaffolds containing regenerated silk fibroin and nanohydroxyapatite for bone tissue regeneration

2011 ◽  
Vol 440 (1) ◽  
pp. 228-230 ◽  
Author(s):  
I. I. Agapov ◽  
M. M. Moisenovich ◽  
T. V. Druzhinina ◽  
Ya. A. Kamenchuk ◽  
K. V. Trofimov ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Silk Fibroin ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
Regenerated Silk Fibroin

Influence of polymer molecular weight in osteoinductive composites for bone tissue regeneration

2013 ◽  
Vol 9 (12) ◽  
pp. 9401-9413 ◽  
Author(s):  
Davide Barbieri ◽  
Huipin Yuan ◽  
Xiaoman Luo ◽  
Silvia Farè ◽  
Dirk W. Grijpma ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
Polymer Molecular Weight

Biofunctional Ionic-Doped Calcium Phosphates: Silk Fibroin Composites for Bone Tissue Engineering Scaffolding

2017 ◽  
Vol 204 (3-4) ◽  
pp. 150-163 ◽  
Author(s):  
S. Pina ◽  
R.F. Canadas ◽  
G. Jiménez ◽  
M. Perán ◽  
J.A. Marchal ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cell Proliferation ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Silk Fibroin ◽  
Tissue Regeneration ◽  
Calcium Phosphates ◽  
Bone Tissue Regeneration ◽  
Osteogenic Potential

The treatment and regeneration of bone defects caused by traumatism or diseases have not been completely addressed by current therapies. Lately, advanced tools and technologies have been successfully developed for bone tissue regeneration. Functional scaffolding materials such as biopolymers and bioresorbable fillers have gained particular attention, owing to their ability to promote cell adhesion, proliferation, and extracellular matrix production, which promote new bone growth. Here, we present novel biofunctional scaffolds for bone regeneration composed of silk fibroin (SF) and β-tricalcium phosphate (β-TCP) and incorporating Sr, Zn, and Mn, which were successfully developed using salt-leaching followed by a freeze-drying technique. The scaffolds presented a suitable pore size, porosity, and high interconnectivity, adequate for promoting cell attachment and proliferation. The degradation behavior and compressive mechanical strengths showed that SF/ionic-doped TCP scaffolds exhibit improved characteristics for bone tissue engineering when compared with SF scaffolds alone. The in vitro bioactivity assays using a simulated body fluid showed the growth of an apatite layer. Furthermore, in vitro assays using human adipose-derived stem cells presented different effects on cell proliferation/differentiation when varying the doping agents in the biofunctional scaffolds. The incorporation of Zn into the scaffolds led to improved proliferation, while the Sr- and Mn-doped scaffolds presented higher osteogenic potential as demonstrated by DNA quantification and alkaline phosphatase activity. The combination of Sr with Zn led to an influence on cell proliferation and osteogenesis when compared with single ions. Our results indicate that biofunctional ionic-doped composite scaffolds are good candidates for further in vivo studies on bone tissue regeneration.

Bioengineered Osteoinductive Broussonetia kazinoki/Silk Fibroin Composite Scaffolds for Bone Tissue Regeneration

2017 ◽  
Vol 9 (2) ◽  
pp. 1384-1394 ◽  
Author(s):  
Do Kyung Kim ◽  
Jeong In Kim ◽  
Tae In Hwang ◽  
Bo Ra Sim ◽  
Gilson Khang
Keyword(s):  
Bone Tissue ◽  
Silk Fibroin ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
Composite Scaffolds
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