scholarly journals An Insight into Pyogenic Granuloma with Ossification: Exploring a Unique Association

Author(s):  
Aparna Dave ◽  
Manpreet Arora ◽  
Pulin Saluja ◽  
Ishita Singhal ◽  
Priyanka Singh

Pyogenic Granulomas (PG) are reactive hyperplastic lesions that are formed in relation to some chronic irritation, physical trauma or hormonal factors. The PG may present in various clinical and histological forms. These often present as a smooth lobulated exophytic lesions and at times may show a marked resemblance to Peripheral Ossifying Fibroma (POF). However, the characteristic histologic presentation helps in differentiating both the lesions. Microscopically, presence of ossification in pyogenic granuloma is not common and could possibly indicate an altered response of the connective tissue stroma. The present case report shows occurrence of pyogenic granuloma in a 12-year-old female which on histological examination not only exhibited proliferating blood vessels, endothelial cells and inflammatory cells which are typical features of pyogenic granuloma but also exhibited areas of ossifications which are not frequently encountered in PG. It is important to explore the underlying aetiological factors that could lead to formation of such ossifications. It has been suggested that pyogenic granuloma and peripheral ossifying fibroma could represent part of same spectrum of focal reactive lesions. However, it is still considered that these two lesions are separate clinical entities and the histologic presentations are different and unique to both of them.

2017 ◽  
Vol 6 (2) ◽  
pp. 1546
Author(s):  
Nabil Khzam ◽  
Reza Shah Mansouri ◽  
Alexander Poli ◽  
Mahmoud M. Bakr

Fibrous epulis or peripheral ossifying fibroma is a reactive non-neoplastic condition that affects the gingiva as a result of chronic irritation. A case of a 44 year old female is presented in this study with a gingival swelling related to the maxillary central incisors. The Patient reported a history of trauma ten years ago and a recent root canal treatment of tooth 21, followed by referral to a specialist with a misdiagnosis for a combined periodontic-endodontic lesion affecting the maxillary central incisors. Excisional biopsy of the lesion revealed a diagnosis of ulcerated fibrous epulis with osseous metaplasia also known as peripheral ossifying fibroma. Periodontal debridement was performed to eliminate supra and subgingival plaque and calculus as well as gingival inflammation that could have been the source of irritation. The clinical and histopathological pictures and the surgical procedures associated with management of the periodontal disease are described. The etiological factor behind the development of the gingival reactive lesion remains unknown and could be the history of trauma, the chronic irritation induced by the plaque and calculus associated with the periodontal disease or a combination of both. We endeavour to follow up the case in order to report any recurrence.


2015 ◽  
Vol 6 (7) ◽  
pp. 524
Author(s):  
Devang Manojkumar Mistry ◽  
Aanal D Mistry ◽  
Ankit H Shah ◽  
Mrugank M Bhavsar

Cureus ◽  
2022 ◽  
Author(s):  
Géssica V Godinho ◽  
Cristhiane A Silva ◽  
Bruno R Noronha ◽  
Everton J Silva ◽  
Luiz E Volpato

2020 ◽  
Vol 6 (2) ◽  
pp. 109-111
Author(s):  
Vinita Thapa ◽  
Preeti Dhawan ◽  
Nitin Khanduri ◽  
Brijesh Gupta

The gingiva is often the site of localize growth that are considered to be reactive rather than neoplastic in nature.Many of these lesions are difficult to be identified clinically and can only be identified by histological examination.Many types of localized reactive lesions occurring on the gingiva includes focal fibrous hyperplasia, pyogenic granuloma, peripheral giant cell granuloma and peripheral ossifying fibroma . Clinical reports of  12 and 13 year old girls with Pyogenic Granuloma and Peripheral ossifying fibroma are presented.


2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Meenakshi Bhasin ◽  
Vinny Bhasin ◽  
Abhilasha Bhasin

Intraoral ossifying fibromas have been described in the literature since the late 1940s. Peripheral ossifying fibroma (POF) is usually a fibroma of the gingival which shows areas of calcification or ossification. It is a nonneoplastic enlargement of gingiva. Due to its clinical and histopathological similarities, some POFs are believed to develop initially as a pyogenic granuloma that undergoes fibrous maturation and subsequent calcification. It has been suggested that POF represents a separate clinical entity rather than a transitional form of pyogenic granuloma or irritation fibroma. This paper describes a case report of a 60-year-old female patient reported with growth on gingiva in the upper left front region of mouth three years ago.


Author(s):  
Dr. Romita Dilip Gaikwad ◽  
Dr. Farooque Khan

The gingiva is often considered as one of the most common sites of localized growths that are considered to be reactive rather than malignant in nature. Clinically, the majority of these lesions are difficult to identify, and therefore histopathology is useful in diagnosing these lesions as specific entities only on the basis of typical and consistent features. Focal gingival enlargements are quite frequent lesions in the oral cavity amounting to almost 3.1% of all oral tumors and 9.6% of gingival lesions. Peripheral ossifying fibroma (POF) is one of the reactive lesions that have typical histopathological features. Since the late 1940s, intraoral ossifying fibromas have been discussed in the literature. The term “Peripheral ossifying fibroma” is usually used to describe a fibroma of the gingiva which shows areas of calcification or ossification. They are usually classified as non-neoplastic enlargement of the gingiva. Many POFs are thought to develop initially as a pyogenic granuloma that undergoes fibrous maturation and subsequent calcification. However, many authors have suggested that rather than a transitional form of pyogenic granuloma or irritation fibroma, POF represents a separate clinical entity. Different lesions with clinical presentations similar to POF make it difficult to arrive at an appropriate diagnosis. Usually, the treatment of POF includes excision of the lesion surgically with minimal chances of recurrence. This paper describes a case report of a 32 year old female patient who reported growth on gingiva in the mandibular left anterior region of the mouth for three years.


2016 ◽  
Vol 06 (02) ◽  
pp. 069-072
Author(s):  
Mithula Nair S. ◽  
Vidya Ajila ◽  
Shruthi Hegde ◽  
G. Subhas Babu ◽  
Rumela Ghosh

AbstractPeripheral ossifying fibroma (POF) is a reactive lesion usually arising from the interdental gingiva. The etiology is considered to be secondary to trauma or other local irritating factors. POF is almost always confused with pyogenic granuloma and peripheral giant cell granuloma. It usually shows a predominance of incidence in anterior region of maxilla and among females. Lesions are rarely larger than 2 cms in size. Incidence of peripheral ossifying fibroma in the posterior maxilla is also rare. Here we report a large peripheral ossifying fibroma occurring in a 40 year old man in the posterior maxillary region which had extended to the occlusal surface of the third molar region causing pain and erythema.


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