Significance of Tissue Microbiopsies in Fine Needle Aspiration Cytology- A Prospective Study

Background: Breast lump is one of the common pathologies seen in surgical practice. Hence it is of importance to have a reliable diagnostic method to distinguish between benign and malignant lumps. Aim of this study was to bring out fine needle aspiration cytology (FNAC) as a rapid, inexpensive, accurate and least invasive diagnostic method for this purpose.Methods: A prospective study conducted between December 2017 to November 2018 on all 30 patients admitted at Rajarajeswari Medical College and Hospital with breast lumps. Patients were subjected to clinical examination FNAC and Histopathology.Results: Clinically 64% were categorized as benign lumps and 36% malignant. On FNAC 64% were fibroadenoma, 30% suggestive of malignancy and 6% suspicious of malignancy. On Histopathology 60% were fibroadenoma, 33% turned out to be carcinoma and 7% benign phyllodes. 4% of benign lesions on FNAC turned out malignant on histopathology.Conclusions: Although son mammography is the conventional approach with a sensitivity of 76.5% and specificity of 90.48%, in this study FNAC was found to have sensitivity of 96.6% and specificity of 100% and can be a reliable tool for early diagnosis in the case of breast lumps.

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Cytomorphological Spectrum of Salivary Gland Lesions by Fine Needle Aspiration Cytology

International Journal of Research and Review ◽

10.52403/ijrr.20210757 ◽

2021 ◽

Vol 8 (7) ◽

pp. 397-401

Author(s):

Mayur Ambekar ◽

Rachana Binayke

Keyword(s):

Salivary Gland ◽

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Minor Salivary Gland ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Fine Needle ◽

Neoplastic Lesions ◽

Needle Aspiration Cytology ◽

A Prospective Study

Introduction: Salivary gland lesions encompass a baffling subset of lesions with overlapping morphologies on cytomorphology, due to their heterogenous histologies and rare enough to sometimes bewilder even the most knowledgeable cytopathologists. The technique of fine needle aspiration (FNA) cytology in the evaluation of salivary gland lesion is simple to perform, saves time, reliable, safe and inexpensive. FNA is highly accurate when used in proper clinical setting and supported by appropriate clinical and relevant diagnostic data. Rapidity of obtaining a pathological diagnosis allows more intelligent therapeutic approach. Materials and Methods: It was a prospective study carried out in the cytology section of pathology department for a period of two years using fine needle aspiration as a diagnostic tool as per standard protocol. The clinical and radiological data were obtained from the patient’s case papers and collaboration with the operating surgeon, the lesions were analysed on cytology. Haematoxylin & Eosin, Papanicolaou stain and Giemsa were used as standard stains. Results: A total of 66 cases of salivary gland lesions were aspirated for a period of two years. Majority of cases were in the age group of 21-30 years with 36 male patients (55%) and 30 female patients (45%). About 44(66.7%), 19(28.8%), 1(1.5%) and 2(3.0%) cases occurred in parotid gland, submandibular gland, sublingual gland and minor salivary gland respectively. There were 21(32%) cases of non-neoplastic lesions and 45(68%) cases of neoplastic lesions. Histopathological specimens were available in 11 out of 66 cases and showed correlation with cytological findings. Conclusion: Fine needle aspiration cytology of salivary gland lesions has high diagnostic accuracy, helps in appropriate therapeutic management and is useful as a diagnostic procedure because of the availability of earlier diagnosis in comparison with the histopathology. Keywords: Salivary gland lesions, fine needle aspiration cytology, neoplastic, non-neoplastic.

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