scholarly journals Modern Solutions in the Treatment of HIV: From Antiretroviral Drug Therapy to Human Genome Editing

2021 ◽  
pp. 159-169
Author(s):  
Milana Ruslanovna Sebaeva ◽  
Iman Vladimirovna Gelogaeva ◽  
Naida Ramizovna Suleymanova ◽  
Kamila Umarovna Balaeva ◽  
Aishat Arslanovna Dauletova ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Sharp Decrease ◽  
Viral Diseases ◽  
Adequate Treatment ◽  
Antiretroviral Drug ◽  
Short Period ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Pathogenic Microbes ◽  
Immunodeficiency Syndrome

The human immunodeficiency virus (HIV) belongs to a group of anthroponotic viral diseases that cause HIV infection in the human body, apotheosely transforming into acquired immunodeficiency syndrome (AIDS). HIV infection, in people without adequate treatment, can lead to serious damage to the immune system (hereinafter referred to as IS), which leads to a sharp decrease in resistance to conditionally pathogenic microbes, as well as to the prevalence of oncological pathologies that may lead to death. Due to its simplicity, convenience, efficiency and cost-effectiveness, CRISPR/Cas has found application in a short period of time in a wide variety of fields of fundamental and applied medicine and biotechnology.

Bacillary Angiomatosis: A Unique Cutaneous Complication of Hiv Infection

1995 ◽  
Vol 3 (2) ◽  
pp. 1-10
Author(s):  
Joan Lipa ◽  
Walter Peters ◽  
Victor Fornasier ◽  
Benjamin Fisher
Keyword(s):  
Hiv Infection ◽  
Definitive Diagnosis ◽  
Causal Organism ◽  
Bacillary Angiomatosis ◽  
Immunodeficiency Virus ◽  
Confirmatory Tests ◽  
Nodular Lesions ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Erythromycin Therapy

As the prevalence of human immunodeficiency virus (HIV) infection increases, so does the recognition of unusual manifestations of this syndrome. This study describes two patients who presented with a unique, rare, cutaneous manifestion of HIV infection. One patient developed an aggressive atypical cellulitis and ascending lymphangitis of the hand, which failed to improve following multiple courses of several different antibiotics. The other patient presented with multiple, vascular, nodular lesions, clinically resembling Kaposi's sarcoma. Routine biopsies and wound cultures were not helpful for diagnosis. A definitive diagnosis of bacillary angiomatosis (BA) was made using a special silver-staining (Warthin-Starry) histological technique and electron microscopy. Both patients responded completely to oral erythromycin therapy. BA is a newly recognized bacterial infection caused by bacteria of the genus Bartonella. It is seen primarily in patients with acquired immunodeficiency syndrome (AIDS), and less commonly in patients with other immunosuppressed conditions. The term BA describes the lesion's pathogenesis (infective-bacillary) and clinico-histology (angiomatosis). The causal organism cannot be cultured reliably and is resistant to most antibiotics. This study reviews these two patients, the differential diagnosis of BA, specific confirmatory tests used in diagnosis, and the treatment outcome of this condition. It is important for the plastic surgeon to understand BA, because it can resemble other common presentations, but it can also be associated with internal involvement leading to mortality. However, when recognized, it can usually be cured by oral erythromycin therapy (500 mg qid) for several weeks.

Decreased Thymus Size on Chest Radiography: A Sign of Pediatric Human Immunodeficiency Virus Infection?

PEDIATRICS ◽  
1992 ◽  
Vol 90 (1) ◽  
pp. 99-102
Author(s):  
ALAN MEYERS ◽  
NICHOLAS PEPE ◽  
WILLIAM CRANLEY ◽  
KATHLEEN MCCARTEN
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hiv Infection ◽  
Chest Radiography ◽  
Pediatric Hiv ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Acquired Immunodeficiency ◽  
Generalized Lymphadenopathy ◽  
Immunodeficiency Syndrome ◽  
Thymus Size

The early diagnosis of infection with the human immunodeficiency virus (HIV) in infancy is clinically important but remains problematic in the asymptomatic child born to an HIV-infected mother. In addition, many such women are unaware of their HIV infection until their child manifests symptomatic HIV disease. Nonspecific signs of pediatric HIV infection, such as generalized lymphadenopathy, hepatosplenomegaly, or persistent thrush, may be important in alerting the clinician to consider the possibility of HIV infection in the child whose history of HIV risk is unknown. We report one such sign which may be evident on plain chest radiography. The pathology of the thymus gland in pediatric acquired immunodeficiency syndrome has been described by Joshi and colleagues,1-3 who have reported precocious involution with marked reduction in thymus size and weight.

Educating podiatric medical assistants about AIDS and HIV infection

1990 ◽  
Vol 80 (1) ◽  
pp. 36-40 ◽  
Author(s):  
CA Holmes
Keyword(s):  
Human Immunodeficiency Virus ◽  
Virus Infection ◽  
Human Immunodeficiency Virus Infection ◽  
Infection Control ◽  
Hiv Infection ◽  
Medical Assistants ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Infection Control Guidelines

In order to assess the need for acquired immunodeficiency syndrome education among podiatric assistants, comprehensive questionnaires on human immunodeficiency virus infection were distributed in February and March 1989. The findings presented here are based upon questionnaires completed and returned by 300 assistants. The purpose of the needs assessment was three-fold: to find out how much the surveyed assistants know about AIDS and HIV infection, how they feel about working with HIV-infected patients, and to what extent they understand and follow recommended infection control practices. The results of the survey reveal that many of the assistants in the sample in this study are ill-informed about HIV infection, that they have numerous concerns and fears about working with HIV-infected patients, and that they are not following recommended infection control guidelines.

scholarly journals Fear of HIV Infection and Impact of Training on the Attitudes of Surgical and Emergency Nurses Toward Inpatient HIV Testing

2007 ◽  
Vol 28 (2) ◽  
pp. 230-233 ◽  
Author(s):  
Maria Gańczak ◽  
Peter Barss
Keyword(s):  
Hiv Infection ◽  
Hiv Testing ◽  
Surgical Patients ◽  
Hiv Positive ◽  
Emergency Nurses ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Testing Policies ◽  
Previous Training

This study evaluates the association between the degree of fear of human immunodeficiency virus (HIV) infection and support for different HIV testing policies. A strong fear of acquiring HIV infection at work was widespread among a sample of 601 Polish surgical and emergency nurses. Most favored inappropriate HIV testing of all surgical patients and inpatients. Previous training about HIV and acquired immunodeficiency syndrome (AIDS) and experience caring for HIV-positive patients had a significant impact on reducing support for testing of all inpatients but not for testing of surgical patients.

scholarly journals KEAMANAN PENGGUNAAN ANESTESI REGIONAL PADA PERSALINAN PENGIDAP HIV

2013 ◽  
Vol 2 (2) ◽  
Author(s):  
Lucky Kumaat
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hiv Infection ◽  
Pregnant Women ◽  
Regional Anesthesia ◽  
Acquired Immunodeficiency Syndrome ◽  
Keywords Hiv ◽  
Immunodeficiency Virus ◽  
Post Operation ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Abstract: Human Immunodeficiency Virus (HIV) infection and Acquired Immunodeficiency Syndrome (AIDS) are the major problems of global health. It is estimated that approximately 75.9% of Human Immunodeficiency Virus (HIV)-infected women aged are in productive ages (20-39 years) with possibilities to become pregnant. Since the prevalence of Human Immunodeficiency Virus infection in pregnant women is increasing, anesthesiologists are increasingly confronting these diseases in their patients. HIV infection in pregnant women often raises questions about the safety of regional anesthesia for them. Fears of the spread of infection to the Central Nervous System (CNS) or the sequel of the neurological system have led some clinicians not to use regional anesthesia. Some research shows that pregnant women with HIV infection are not a contraindication for regional anesthesia since there is no CNS and neurological sequel or infection after a long enough time post operation. Keywords: HIV infection, AIDS, parturition, regional anaesthesia.  Abstrak: Infeksi Human Immunodeficiency Virus (HIV) dan Acquired Immunodeficiency Syndrome (AIDS) adalah masalah utama dari kesehatan global. Diperkirakan sekitar 75,9% wanita yang terinfeksi HIV berada pada usia produktif (20-39 tahun) yang berpeluang untuk hamil. Karena prevalensi infeksi HIV pada wanita hamil semakin meningkat, maka ahli anestesi semakin banyak diperhadapi dengan pasien demikian. Infeksi HIV pada wanita hamil seringkali memunculkan pertanyaan mengenai keamanan penggunaan anestesi regional pada mereka. Kekuatiran terhadap penyebaran infeksi ke sistim susunan saraf pusat (SSP) atau sekuel neurologik menyebabkan sebagian klinisi menentang penggunaan anestesi regional. Beberapa penelitian telah membuktikan bahwa wanita hamil dengan HIV bukan merupakan kontraindikasi bagi penggunaan anestesi regional karena tidak dijumpai adanya infeksi SSP atau sekuel neurologik setelah selang waktu yang cukup panjang pasca operasi. Kata kunci: Infeksi HIV, AIDS, persalinan, anestesi regional.

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